A5009014905- Luminescence and Fluorescent Materials
- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Molecular Sensors and Ion Detection
- Organic Light-Emitting Diodes Research
- Osteoarthritis Treatment and Mechanisms
- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Advanced Nanomaterials in Catalysis
- Fuel Cells and Related Materials
- Cellular Mechanics and Interactions
- Lanthanide and Transition Metal Complexes
- Perovskite Materials and Applications
- Periodontal Regeneration and Treatments
- Knee injuries and reconstruction techniques
- Advanced Battery Technologies Research
- Photochemistry and Electron Transfer Studies
- Advanced Battery Materials and Technologies
- Graphene and Nanomaterials Applications
- Electrospun Nanofibers in Biomedical Applications
- Advancements in Battery Materials
- Analytical chemistry methods development
- Silk-based biomaterials and applications
- Mesenchymal stem cell research
- Liver physiology and pathology
Shenzhen University
2020-2025
National University of Singapore
2011-2024
Shandong University
2019-2024
Hangzhou Medical College
2022
Zhejiang Provincial People's Hospital
2022
Second Affiliated Hospital of Guangzhou Medical University
2022
Guangzhou Medical University
2022
Qingdao Center of Resource Chemistry and New Materials
2019-2021
Ping An (China)
2021
Materials Science & Engineering
2021
Abstract Polydimethylsiloxane (PDMS) has been extensively exploited to study stem cell physiology in the field of mechanobiology and microfluidic chips due their transparency, low cost ease fabrication. However, its intrinsic high hydrophobicity renders a surface incompatible for prolonged adhesion proliferation. Plasma-treated or protein-coated PDMS shows some improvement but these strategies are often short-lived with either aggregates formation sheet dissociation. Recently, chemical...
Type I photosensitization provides an effective solution to the problem of unsatisfactory photodynamic therapeutic (PDT) effects caused by tumor hypoxia. The challenge in development mode is boost photosensitizer's own electron transfer capacity. Herein, we found that use bovine serum albumin (BSA) encapsulate a thermally activated delayed fluorescence (TADF) photosensitizer PS can significantly promote PDT process generate mass superoxide anions (O2•–). This opened new strategy employing...
OPBI-0.8AM membrane can operate from 80–160 °C which break through the limits of existing HT-PEMFCs materials.
Reactive oxygen species (ROS)-induced cell apoptosis has emerged as an efficient strategy for cancer therapy. However, tumor hypoxia and insufficient amounts of endogenous hydrogen peroxide (H2O2) in the microenvironment are currently main limitations photodynamic therapy (PDT) chemodynamic (CDT). Moreover, glutathione (GSH) scavenging effect on ROS further hinders efficiency ROS-mediated Here, a CaO2-based nanosystem (named CF@CO@HC) with self-amplification GSH-depletion abilities was...
Abstract Molecular phototheranostic dyes are of eminent interest for oncological diagnosis and imaging‐guided phototherapy. However, it remains challenging to develop photosensitizers (PSs) that simultaneously integrate high‐contrast photoacoustic imaging efficient therapeutic capabilities. In this work, a supramolecular strategy is employed construct molecular pair agent via the direct self‐assembly two cyanines, C5TNa (anionic) Cy‐Et (cationic). The Coulombic interactions between...
Considering the load-bearing physiological requirement of articular cartilage, scaffold for cartilage tissue engineering should exhibit appropriate mechanical responses as natural undergoing temporary deformation on loading with little structural collapse, and recovering to original geometry unloading. A porous elastomeric poly l-lactide-co-ɛ-caprolactone (PLCL) was generated crosslinked at surface chitosan improve its wettability. Human bone marrow derived mesenchymal stem cells (MSC)...
Stem cell differentiation is guided by contact with the physical microenvironment, influence both topography and mechanical properties of matrix. In this study, combined effect substratum nano-topography stiffness in directing mesenchymal stem (MSC) chondrogenesis was investigated. Three polyesters varying were thermally imprinted to create nano-grating or pillar patterns same dimension. The surface nano-patterned substrate coated chondroitin sulfate (CS) provide an even chemistry,...
Abstract Abnormal endometrial receptivity is a major cause of the failure embryo transplantation, which may lead to infertility, adverse pregnancy, and neonatal outcomes. While hormonal treatment has dramatically improved fertility outcomes in women with endometriosis, substantial unmet need persists treatment. In this study, methacrylate gelatin (GelMA) sericin (SerMA) hydrogel human umbilical cord mesenchymal stem cells (HUMSC) encapsulation was designed for facilitating regeneration...
Mitochondria-targeting photodynamic therapy (PDT) can block mitochondrial function and trigger the inherent proapoptotic cascade signal of mitochondria, which has been considered to have potential amplify efficiency PDT. However, dynamic change membrane (MMP) makes most cationic photosensitizers easily fall off from greatly limits Here, we developed a smart liposome encapsulation method based on mitochondria-stapling photosensitizer for efficient theranostic therapy. The stapling be...
A new photon up-conversion system with a TADF fluorescein derivative as photosensitizer was developed to achieve quite large anti-Stokes shift from red blue fairly high emission quantum yield.
In this study, a near-infrared (NIR) theranostic photosensitizer was developed based on heptamethine aminocyanine dye with long-lived triplet state.
Chemiluminogenic bioimaging has emerged as a promising paradigm due to its independence from light excitation, thereby circumventing challenges related penetration depth and background autofluorescence. However, the availability of effective chemiluminophores remains limited, which substantially impedes their bio-applications. Herein, we discovered for first time that cyclometalated iridium(III) Schiff base complexes can unexpectedly generate chemiluminescence. Notably, chemiluminescence...
A reaction-based luminescence chemosensor was synthesized for sulfite detection based on a fluorescein derivative with thermally activated delayed fluorescence (TADF).
A probe was synthesized that could detect Zn<sup>2+</sup> using AIE in plants and zebrafish.