Lei Zhong

ORCID: 0000-0002-0208-1823
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Research Areas
  • Cancer Genomics and Diagnostics
  • Genetic factors in colorectal cancer
  • Rice Cultivation and Yield Improvement
  • Prostate Cancer Treatment and Research
  • Sepsis Diagnosis and Treatment
  • Plant nutrient uptake and metabolism
  • Renal function and acid-base balance
  • Science, Research, and Medicine
  • Phytase and its Applications
  • Plant Micronutrient Interactions and Effects
  • Plant responses to water stress
  • Cancer Treatment and Pharmacology
  • Acute Kidney Injury Research
  • Cardiac Arrest and Resuscitation
  • Hemodynamic Monitoring and Therapy
  • Catalytic Processes in Materials Science
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Soil Carbon and Nitrogen Dynamics
  • Nanoplatforms for cancer theranostics
  • Radiomics and Machine Learning in Medical Imaging
  • Plant Stress Responses and Tolerance
  • Colorectal Cancer Treatments and Studies
  • Cancer, Hypoxia, and Metabolism
  • Cardiovascular Function and Risk Factors
  • Inflammatory Biomarkers in Disease Prognosis

Huzhou Central Hospital
2020-2025

Huzhou University
2022-2025

Zhejiang Chinese Medical University
2023-2025

Harbin Medical University
2023-2025

Tianjin University
2022-2025

Shanghai Traditional Chinese Medicine Hospital
2025

Kunming Medical University
2023-2024

Harbin Institute of Technology
2022-2024

The Synergetic Innovation Center for Advanced Materials
2023-2024

Nanjing Tech University
2023-2024

Abstract Aims Acute myocardial infarction (AMI) is a cardiovascular disease with high morbidity and mortality. We collected patients AMI from the Medical Information Mart for Intensive Care IV (v2.0) database explored association between serum albumin‐corrected anion gap (ACAG) level mortality in AMI. Methods results Data of adult were collected. According to 360 day prognosis, divided into survival non‐survival groups. Based on ACAG level, then normal Cox hazard proportional models...

10.1002/ehf2.14639 article EN cc-by-nc-nd ESC Heart Failure 2024-01-02

Based on ecological crop nutrient deficiency and compensation effect theory, the nitrogen (N) sensitive stage of rice (Oryza sativa L.) was selected to study N at tillering young panicle differentiation stage. Four treatments were treated effects investigated grain yield, uptake utilization physiological characteristics rice. The results showed that yield per plant presented an equivalent compensatory effect. Double led superiority in number effective panicles plant, increased activities...

10.3389/fpls.2018.01075 article EN cc-by Frontiers in Plant Science 2018-07-24

The relationship between albumin corrected anion gap (ACAG) and mortality in acute kidney injury (AKI) patients who received continuous renal replacement therapy (CRRT) has not been investigated any previous studies. This study aimed to investigate the ACAG at CRRT initiation all-cause among these intensive care unit (ICU). Patients diagnosed with AKI treated ICU from Medical Information Mart for Intensive Care-IV version 1.0 (MIMIC IV) database Huzhou Central Hospital were retrospectively...

10.1007/s11739-022-03093-8 article EN cc-by Internal and Emergency Medicine 2022-09-16

Proteins and phenolic compounds are common components in foods that readily interact with each other to yield complexes, leading changes the functional properties. In this study, we investigated effect of covalent conjugation rice protein hydrolysates (RPH) chlorogenic acid (CA) on structural properties RPH. Three RPH-CA conjugates were prepared by alkaline, enzyme, free radical methods, respectively. Covalent decreased content amino, thiol, tyrosine groups, increased amount CA bounds from...

10.1016/j.fochx.2022.100352 article EN cc-by-nc-nd Food Chemistry X 2022-05-28

Ferroptosis, as a non-apoptotic cell death pathway, has attracted increasing attention for cancer therapy. However, the clinical application of ferroptosis-participated modalities is severely limited by low efficiency owing to intrinsic intracellular regulation pathways. Herein, chlorin e6 (Ce6) and N-acetyl-l-cysteine-conjugated bovine serum albumin-ruthenium dioxide elaborately designed constructed ultrasound-triggered peroxynitrite-mediated ferroptosis. Upon ultrasound stimulation,...

10.1002/smll.202303057 article EN Small 2023-07-11

Objective To explore the relationship between lactate-to-albumin ratio (LAR) at ICU admission and prognosis in critically ill patients with acute kidney injury (AKI).

10.1080/0886022x.2024.2350238 article EN cc-by-nc Renal Failure 2024-05-09

BackgroundSepsis is a prevalent and severe medical condition which frequently observed in the intensive care unit (ICU). Although numerous biomarkers have been identified to predict prognosis of sepsis, lactate dehydrogenase albumin ratio (LDH/ALB ratio) has not extensively investigated. The principal objective this study assess relationship between LDH/ALB all-cause mortality patients with sepsis.MethodsThis included all adult critically ill sepsis from Medical Information Mart for...

10.1016/j.heliyon.2024.e27560 article EN cc-by-nc-nd Heliyon 2024-03-01

Background The primary objective was to examine the association between lactate/albumin ratio (LAR) and prognosis of patients with acute kidney injury (AKI) undergoing continuous renal replacement therapy (CRRT).

10.1080/0886022x.2024.2374451 article EN cc-by-nc Renal Failure 2024-07-05

Abrupt drought-flood alternation (T1) is a meteorological disaster that frequently occurs during summer in southern China and the Yangtze river basin, often causing significant loss of rice production. In this study, response mechanism yield decline under abrupt stress at panicle differentiation stage was analyzed by looking metabolome, proteome as well physiological biochemical indexes. The results showed drought flood caused decrease stage, created synergistic effect for reduction yield....

10.1111/ppl.12901 article EN Physiologia Plantarum 2018-12-18

Abstract Background Nitrogen application can effectively mitigate the damage to crop growth and yield caused by drought. However, efficiency of heavy nitrogen before drought (NBD) after (NAD) regulate rice response stress remains controversial. In this study, we profiled physiology, proteomics metabolomics in variety Wufengyou 286 two management modes (NBD NAD) investigate their formation mechanism regulation for resistance. Results revealed that NBD NAD decreased significantly when it was...

10.1186/s12870-020-02772-y article EN cc-by BMC Plant Biology 2020-12-01

A versatile nanoparticle based on the hollow structure of Prussian blue (HCLP NPs) is developed for dual-inhibition lactate metabolism and enhanced chemodynamic therapy.

10.1039/d3nr01052j article EN Nanoscale 2023-01-01

Abstract Okara, a renewable biomass resource, is promising fermentative raw material for the bio-production of value-added chemicals due to its abundance and low-costs. we developed process enzymatic hydrolysis okara, then engineered Bacillus subtilis utilize mixed sugars produce acetoin in okara without addition supplemental nitrogen source. Okara was initially hydrolyzed with cellulase, β-glucosidase, pectinase obtain hydrolysate containing (32.78 ± 0.23 g/L glucose, 1.43 0.064 arabinose,...

10.1186/s13568-023-01532-z article EN cc-by AMB Express 2023-02-28

Background The early identification of patients at high risk for acute kidney injury (AKI) with a poor prognosis is crucial to prevent complications and minimize mortality. This study sought investigate the association between albumin-corrected anion gap (ACAG) all-cause mortality among critically ill AKI.

10.1080/0886022x.2023.2282708 article EN cc-by-nc Renal Failure 2023-11-17

The development of ozone-decomposition catalysts with high efficiency and exceptional resistance to humidity is a significant challenge, as ozone primary air pollutant. This study successfully synthesized series MnxFe3–xO4 varying crystal structures by adjusting the Mn/Fe molar ratios through coprecipitation method inorganic salt precursors. Compared crystalline Mn3O4 Fe2O3, obtained amorphous MnFe2O4(MnFe-1) nanocatalyst exhibited an optimal conversion rate 99.9% for 50 ppm O3 space...

10.1021/acsanm.3c06173 article EN ACS Applied Nano Materials 2024-03-14
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