Bo Xie

ORCID: 0000-0003-0458-4202
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About
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Research Areas
  • Clinical Nutrition and Gastroenterology
  • Nutrition and Health in Aging
  • Dental Anxiety and Anesthesia Techniques
  • Abdominal Surgery and Complications
  • Cancer, Lipids, and Metabolism
  • Sepsis Diagnosis and Treatment
  • Respiratory and Cough-Related Research
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Acute Kidney Injury Research
  • Bladder and Urothelial Cancer Treatments
  • Cancer Risks and Factors
  • Liver Disease Diagnosis and Treatment
  • Empathy and Medical Education
  • Fatty Acid Research and Health
  • Respiratory Support and Mechanisms
  • Cardiac Arrest and Resuscitation
  • Electrolyte and hormonal disorders
  • Inflammatory Biomarkers in Disease Prognosis
  • Vascular Procedures and Complications
  • Lipid metabolism and disorders
  • Enhanced Recovery After Surgery
  • Multiple and Secondary Primary Cancers
  • Delphi Technique in Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pain Mechanisms and Treatments

Central South University
2019-2025

Zhuzhou Central Hospital
2025

The Affiliated Yongchuan Hospital of Chongqing Medical University
2025

Chongqing Medical University
2025

Zhejiang Chinese Medical University
2023-2024

Huzhou Central Hospital
2002-2024

Huzhou University
2022-2023

Zhejiang University
2016-2022

Shenzhen Nanshan Center for Chronic Disease Control
2018-2021

First Affiliated Hospital Zhejiang University
2021

In 2012, the European Society of Intensive Care Medicine proposed a definition for acute gastrointestinal injury (AGI) based on current medical evidence and expert opinion. The aim present study was to evaluate feasibility using AGI grading system investigate association between severity grades with clinical outcome in critically ill patients. Adult patients at 14 general intensive care units (ICUs) an expected ICU stay ≥24 h were prospectively studied. grade assessed daily basis (GI)...

10.1186/s13054-017-1780-4 article EN cc-by Critical Care 2017-07-14

The relationship between albumin corrected anion gap (ACAG) and mortality in acute kidney injury (AKI) patients who received continuous renal replacement therapy (CRRT) has not been investigated any previous studies. This study aimed to investigate the ACAG at CRRT initiation all-cause among these intensive care unit (ICU). Patients diagnosed with AKI treated ICU from Medical Information Mart for Intensive Care-IV version 1.0 (MIMIC IV) database Huzhou Central Hospital were retrospectively...

10.1007/s11739-022-03093-8 article EN cc-by Internal and Emergency Medicine 2022-09-16

Abstract Motivation: Polyadenylation is the addition of a poly(A) tail to an RNA molecule. Identifying DNA sequence motifs that signal tails essential improved genome annotation and better understanding regulatory mechanisms stability mRNA. Existing motif predictors demonstrate information extracted from surrounding nucleotide sequences candidate can differentiate true false ones great extent. A variety sophisticated features has been explored, including sequential, structural, statistical,...

10.1093/bioinformatics/btt218 article EN cc-by-nc Bioinformatics 2013-06-19

The role of skeletal muscle in the prognosis patients with Type 2 Diabetes Mellitus (T2DM) remains unclear. This study aimed to systematically evaluate impact different muscle-mass adjustment standards on adverse health outcomes middle-aged and elderly T2DM patients. Retrospective cohort study. A total 1,818 aged 50 years or older were included this comprised 45.7% females, a median age 63 years. Variables closely correlated lean mass (TLM) appendicular (ALM) selected as indicators. primary...

10.1038/s41598-025-92860-6 article EN cc-by-nc-nd Scientific Reports 2025-03-07

Serum lipids have been associated with an increased risk of various cardiovascular diseases (CVDs) in several observational studies, but the causal inference between remnant cholesterol (RC) levels and CVDs has not established. The purpose this study was to investigate whether there is a relationship RC developing by bidirectional two-sample Mendelian randomization (TSMR) analysis. One TSMR analysis performed using publicly released large-scale genome-wide association (GWAS) data. Inverse...

10.1038/s41598-024-78610-0 article EN cc-by-nc-nd Scientific Reports 2024-11-07

Enteral feed is an important component of nutritional therapy in critically ill patients and underfeeding has been associated with adverse outcomes. The article developed enteral feeding protocol planed a before-and-after comparative trial to explore whether implementation was able improve clinical outcomes.The study will be conducted intensive care units (ICUs) ten tertiary academic centers. Critically expected stay ICU for over 3 days require nutrition (EN) were potentially eligible. This...

10.21037/atm.2016.07.15 article EN Annals of Translational Medicine 2016-08-01

Abstract Background The 2012 European Society of Intensive Care Medicine (ESICM) guidelines provided a clear definition feeding intolerance (FI). study aimed to investigate the association between FI based on current ESICM and clinical outcome further explore effect duration mortality. Methods Adult patients from 14 general intensive care units (ICUs) with an expected ICU stay ≥24 hours were prospectively studied. Based in first week admission ICU, was categorized as 7‐day persistent...

10.1002/jpen.1693 article EN Journal of Parenteral and Enteral Nutrition 2019-08-20

Abstract Background Dental anxiety (DA) has an impact on the quality of dental treatment and may have long-lasting implications for children. A recent study introducing experiential learning (EL) into children's oral health promotion resulted in better hygiene. The purpose is to evaluate whether EL can reduce DA. Methods In September 2018, we recruited 988 children aged 7-8 years from 24 classes participate a cluster-randomized trial. Classes were randomly assigned (in which received lively...

10.21203/rs.3.rs-17207/v1 preprint EN cc-by Research Square (Research Square) 2020-03-13

Recently, a novel H7N9 avian influenza A virus has led to human outbreak in China. Here we report 64-year old man with possible history of chronic bronchitis died from the infection Huzhou City, Zhejiang Province Eastern The patient had been exposed poultry before disease onset. Phylogenetic analyses hemagglutinin and neuraminidase genes showed close genetic relationship between viruses booths where he visited, indicating that may have infected poultry. Two venders contacts were negative for...

10.1038/emi.2013.28 article EN cc-by-nc Emerging Microbes & Infections 2013-01-01

Enteral nutrition (EN) feeding protocol was proposed to have positive impact on critically ill patients. However, current studies showed conflicting results. The present study aimed investigate whether enteral able improve clinical outcomes in patients.A before (stage 1) and after 2) interventional performed 10 tertiary care hospitals. All patients expected stay the intensive unit (ICU) for over three days were potentially eligible. Clinical such as 28-day mortality, ICU length of stay,...

10.1371/journal.pone.0182393 article EN cc-by PLoS ONE 2017-08-03

Norepinephrine (NE) has currently been the first-choice vasopressor in treating septic shock despite generally insufficient for patients with refractory shock. The aim of this update meta-analysis was to assess safety and efficacy a combination non-catecholamine vasopressors (vasopressin/pituitrin/terlipressin/selepressin/angiotensin II) NE versus managing adult patients.We conducted study literatures published from inception April 30, 2020, using PubMed, Embase, Cochrane Library databases...

10.1186/s40560-020-00500-0 article EN cc-by Journal of Intensive Care 2020-10-31

Abstract: This meta-analysis aimed to evaluate the correlation between pesticide exposure and kidney cancer. We conducted a systematic search of Cochrane Library, Embase, Web Knowledge, Medline (updated March 1, 2015) identify all relevant studies. References retrieved articles were also identified. Fixed- or random-effect models used summarize estimates relative risk (RR) with 95% confidence interval for association The pooled RR estimate indicated that might have an elevated cancer (RR...

10.2147/ott.s104334 article EN OncoTargets and Therapy 2016-06-01

// Bo Xie 1, * , Guanjun Zhang 2, Xiao Wang 3 and Xin Xu 1 Department of Urology, Tongde Hospital Zhejiang Province, Hangzhou, 310012, China 2 Traditional Chinese Medicine Shangyu, Shangyu 312300, Zhejiang, First Affiliated Hospital, School Medicine, University, 310003, These authors contributed equally to this work Correspondence to: Xie, email: drxiebo2012@163.com Xu, drxuxin@zju.edu.cn Keywords: body mass index, prostate cancer, meta-analysis, dose-response, cohort Received: May 30,...

10.18632/oncotarget.20930 article EN Oncotarget 2017-09-15

Dental anxiety (DA) has an impact on the quality of dental treatment and may have long-lasting implications for children. A recent study introducing experiential learning (EL) into children's oral health promotion resulted in better hygiene. The purpose is to evaluate whether EL can reduce DA.In September 2018, we recruited 988 children aged 7-8 years from 24 classes participate a cluster-randomized trial. Classes were randomly assigned (in which received lively presentation participated...

10.1186/s12903-020-01204-5 article EN cc-by BMC Oral Health 2020-07-31

Objective: Pain and affective disorders have clear clinical relevance; however, very few studies investigated the association between pain bipolar disorder. This study brain activity of patients with disorder (BPs) undergoing tonic assessed interaction emotion. Methods: Ten BPs ten healthy controls (HCs) were exposed to emotional pictures (positive, neutral, or negative), only (pain session), along (combined session). A moderate was induced by infusion hypertonic saline (5% NaCl) into right...

10.3389/fpsyt.2018.00555 article EN cc-by Frontiers in Psychiatry 2018-11-05

Until today, it is unclear if endoscopic or microscopic transsphenoidal surgery the most adequate treatment technique for pituitary adenoma, while termed as a fully-established mechanism that has reasonable performances and well recognized addressing adenomas of gland. The present research work aims at assessing short-term results these surgical methodologies in those patients, who have adenoma.The authors comprehensively searched PubMed, together with EMBASE, Cochrane Library databases...

10.1097/scs.0000000000005676 article EN Journal of Craniofacial Surgery 2019-07-01

Aim: To analyze the metabolites of most common sepsis-related pathogen and their correlation with clinical indicators. Methods: Information bacterial-infection patients in Huzhou Central hospital was retrospectively investigated analyzed. The inducing sepsis selected. Then, metabolic profiles pathogens from blood were detected by liquid chromatography/mass spectrometry. Cluster classification analysis, KEGG pathway enrichment multidimensional OPLS-DA, Z scores, analysis used to metabolites....

10.2147/idr.s388034 article EN cc-by-nc Infection and Drug Resistance 2022-12-01

Abstract Aims There has been a lack of research examining the relationship between red cell distribution width (RDW) and prognosis cardiac arrest (CA) patients. The prognostic value changes in RDW during intensive care unit (ICU) hospitalization for CA patients not investigated. This study aims to investigate correlation measures at ICU admission then develop nomogram that predicts risk mortality these Methods results A retrospective cohort is used collect clinical characteristics (>18...

10.1002/ehf2.14602 article EN cc-by-nc-nd ESC Heart Failure 2023-11-29
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