A5005808377- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Urological Disorders and Treatments
- Ureteral procedures and complications
- Prostate Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Urinary Tract Infections Management
- Anorectal Disease Treatments and Outcomes
- Pediatric Urology and Nephrology Studies
- Botulinum Toxin and Related Neurological Disorders
- Organ Donation and Transplantation
- Spinal Dysraphism and Malformations
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Renal Transplantation Outcomes and Treatments
- Hernia repair and management
- Kidney Stones and Urolithiasis Treatments
- Renal and Vascular Pathologies
- Urinary and Genital Oncology Studies
- Health, Medicine and Society
- Pelvic and Acetabular Injuries
- Neurological Complications and Syndromes
- Hormonal and reproductive studies
- Sexual function and dysfunction studies
- Vagus Nerve Stimulation Research
The Enteric Nervous System in Gut and Brain Disorders
2016-2025
Inserm
2019-2025
Nantes Université
2017-2025
Centre Hospitalier Universitaire de Nantes
2016-2025
Southmead Hospital
2022-2024
Institut de Transplantation Urologie en Nephrologie
2019-2022
Centre d'Investigation Clinique de Nantes
2017-2021
Groupe de Recherche en Énergie Électrique de Nancy
2020
Groupe de Recherche Clinique en Neuro-urologie
2020
Centre Hospitalier Régional Universitaire de Brest
2011-2019
A subgroup of patients with chronic pelvic pain (CPP) exhibit organ sensitization, whose origin and mechanism remains largely unknown. Changes in microbiota composition organs have been found to be associated various pathological conditions. Therefore, a comprehensive analysis the gut genito-urinary interactions women CPP may key understanding their involvement sensitization processes. To identify signatures that are hypersensitivity patients. This study involved high (S-CPP, n=14) low...
Bladder augmentation (BA) is the gold standard treatment to increase compliance and treat neurological detrusor overactivity (DO) in children with bladder refractory medical treatment. In pediatrics, bivalve cystoplasty (Clam) preferred supratrigonal cystectomy. Our initial aim was evaluate re-intervention rate long-term outcomes of BA relation Clam children. The secondary evaluation DO during follow up after cystoplasty. A retrospective analysis performed including all patients < 18 years...
We aim to describe the ProACT implantation using flexible cystoscopic guidance and report long-term outcomes in these patients. This single-centre retrospective study include all men who underwent ProACT™ for SUI after RP between 2007 2021. The was performed via a perineal approach under general or locoregional anaesthesia. Accurate positioning ensured both real-time fluoroscopic endoscopic (flexible cystoscopy retroflexed toward bladder neck). In total, 196 were included; 18% (n = 36) had...
Background: Sacral neuromodulation (SNM) is commonly used in the treatment of overactive bladder, but few studies have evaluated its efficacy patients with multiple sclerosis (MS). Objectives: To assess SNM neurogenic bladder (nOAB) MS. Methods: All MS that underwent a two-stage to treat nOAB between 2013 and 2023 four university hospitals were considered eligible. The primary outcome was clinical efficacy, defined as implantation an implantable pulse generator (IPG). Secondary included...
ABSTRACT Objectives To identify factors that can predict both test phase and midterm success of sacral neuromodulation (SNM) in refractory non‐neurogenic overactive bladder syndrome (nnOAB) based on preoperative clinical urodynamic data. Materials Methods We conducted a two‐center retrospective study included all individuals with nnOAB who underwent between 2005 2021, or without subsequent implantation an SNM device. Only those assessment data were included. was defined as 50% improvement...
To report the long-term complications of continent cutaneous urinary diversion(CCUD) in spinal cord injured(SCI) patients unable to perform intermittent self-catheterization(ISC) through urethra.Between July 2001 and January 2012, adult SCI with a neurogenic bladder who underwent CCUD according Mitrofanoff's/Monti's/Casale's principle were enrolled. A concomitant supratrigonal augmentation enterocystoplasty performed because refractory detrusor overactivity or low compliance. Early...
Aims The primary aim of the RELAX‐OAB study is to confirm safety and efficacy Axonics r‐SNM System, a miniaturized, rechargeable SNM system. Methods A total 51 OAB patients were implanted in single‐stage implant procedure. These results represent 3‐month outcomes. Subject outcomes evaluated using 3‐day bladder diaries quality life questionnaires. Results 31 34 (91%) that responded during an initial trial period (“Test Responders”) continued benefit from therapy with System at 3‐months,...
Historically, providing SNM therapy required use of a non-rechargeable implantable pulse generator (IPG) with an average device lifespan 4.4 years. Multiple replacement surgeries are necessary this for long-term overactive bladder (OAB) management. A longer-lived can reduce and potentially eliminate the need surgeries, thereby improving safety cost-effectiveness therapy. The objective study was to evaluate efficacy miniaturized, rechargeable system.This prospective, multi-center implanted 51...
Sacral neuromodulation is a guideline recommended treatment of urinary dysfunction and fecal incontinence in patients whom conservative treatments have failed. Historically sacral has been delivered using nonrechargeable device with an average life span 4.4 years. Surgery required to replace the implanted neurostimulator due battery depletion. Implantation long-lived can eliminate need for replacement surgeries, potentially reducing patient surgical risks health care costs. The Axonics r-SNM...
Abstract Aims Sacral neuromodulation (SNM) is a guideline‐recommended treatment with proven therapeutic benefit for urinary urgency incontinence (UUI) patients. The Axonics® System the first Food and Drug Administration‐approved rechargeable SNM system designed to deliver therapy minimum of 15 years. ARTISAN‐SNM study was evaluate UUI participants treated Axonics System. Two‐year follow‐up results are presented. Methods One hundred twenty‐nine underwent implantation Therapeutic response...
Abstract Aims To address the predictive factors of a successful voiding after bladder outflow resistance reduction surgery (BORRS) in men presenting with acute or chronic urinary retention (UR). Methods A think tank (TT) ICI‐RS was gathered 2023, Bristol, UK, to discuss several aspects problem, such as pathophysiology UR, clinical and urodynamic evaluation UR whether it is possible predict which will be able successfully void treatment contemporary surgical options. Results The TT agreed...
Objective: Compared with standard systematic transrectal ultrasound (TRUS)-guided biopsies (SBx), targeted (TBx) using magnetic resonance imaging (MRI)/TRUS fusion could increase the detection of clinically significant prostate cancer (PCa-s) and reduce non-significant PCa (PCa-ns). This study aimed to compare performance two approaches.Materials methods: A prospective, single-center was conducted on all consecutive patients suspicion who underwent prebiopsy multiparametric MRI (mpMRI)...
Many studies have demonstrated a link between pelvic floor myofascial syndromes and chronic pain. Botulinum toxin has been extensively used for several years in the field of pain, especially due to its action on muscle spasm. However, efficacy botulinum context pain remains controversial. This multicentre, randomized, controlled, double-blind study was designed compare local anaesthetic (LA) injection versus LA alone syndrome According number painful trigger points detected physical...
We evaluated the perioperative and long-term functional outcomes of bladder neck peribulbar cuff placement an artificial urinary sphincter in a population adult male patients with spinal dysraphism.We retrospectively analyzed French spina bifida network database. Patients who underwent implantation from January 1985 to November 2015 were selected stratified into 2 groups according location, that is vs bulbar urethra. Explantation-free revision-free device survival was estimated by...