Deniz Büyükgök

ORCID: 0000-0002-0232-7715
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Research Areas
  • Attention Deficit Hyperactivity Disorder
  • Functional Brain Connectivity Studies
  • Epilepsy research and treatment
  • Child and Adolescent Psychosocial and Emotional Development
  • Autism Spectrum Disorder Research
  • Problem Solving Skills Development
  • LGBTQ Health, Identity, and Policy
  • Obsessive-Compulsive Spectrum Disorders
  • Personality Traits and Psychology
  • Neural and Behavioral Psychology Studies
  • Cerebrospinal fluid and hydrocephalus
  • Bipolar Disorder and Treatment
  • Participatory Visual Research Methods
  • Discrimination and Equality Law
  • Personality Disorders and Psychopathology
  • Transcranial Magnetic Stimulation Studies
  • Sleep and Wakefulness Research
  • Nerve injury and regeneration
  • Sleep and related disorders
  • HIV, Drug Use, Sexual Risk
  • Long-Term Effects of COVID-19
  • Vitamin D Research Studies
  • Neurotransmitter Receptor Influence on Behavior
  • Bullying, Victimization, and Aggression
  • HIV/AIDS Research and Interventions

Istanbul University
2012-2024

University of Iowa
2024

Istanbul Medipol University
2020

Abstract In the present study, we have tested hypothesis that brain‐derived neurotrophic factor ( BDNF ) gene Val66Met polymorphism is associated with obsessive–compulsive disorder (OCD) and also investigated association between performance on tests measuring executive functions in a sample of patients OCD. A total 100 diagnosed OCD according to DSM‐IV criteria 110 control subjects were included this study. Single nucleotide (G/A) leading Val Met substitution at codon 66 was screened DNA...

10.1002/ajmg.b.32092 article EN American Journal of Medical Genetics Part B Neuropsychiatric Genetics 2012-08-22

Purpose Diagnosis of comorbid psychiatric conditions are a significant determinant for the prognosis neurodegenerative diseases. Apathy, which is behavioral executive dysfunction, frequently accompanies Alzheimer's disease (AD) and leads to higher daily functional loss. We assume that frontal lobe hypofunction in apathetic AD patients more apparent than without apathy. This study aims address neuroanatomical correlates apathy early stage using task-free magnetic resonance imaging (MRI)....

10.5152/dir.2019.19445 article EN Diagnostic and Interventional Radiology 2020-05-28

This study investigated the association between catechol-O-methyl transferase (COMT) Val158Met polymorphism and executive functions in 101 patients with obsessive-compulsive disorder (OCD) 100 healthy-control subjects (HS). Results showed that there was no significant difference for genotype distributions OCD HS groups. OCD-Met carrier subgroup's TMT B-A lexical fluency scores were found to be significantly poorer than both subgroups. These findings suggest lower activity of COMT associated...

10.1176/appi.neuropsych.12040103 article EN Journal of Neuropsychiatry 2013-06-17

Background The relationship between vitamin D and cognitive status remains controversial. We aimed to evaluate the effect of replacement on functions in healthy cognitively intact deficient older females. Methods This study was designed as a prospective interventional study. A total 30 female adults aged ≥60 with serum 25 (OH) level <10 ng/ml were included. Participants administered 50 000 IU D3 weekly for 8 weeks followed by maintenance therapy 1000 U/day. Detailed neuropsychological...

10.1111/psyg.12997 article EN Psychogeriatrics 2023-06-30

Objectives Mental health (MH) care for people living with HIV (PLWH) emerges as an important unmet need, yet there are no integrated HIV-MH clinics in Turkey. Our aim is to determine MH service use and its associated factors PLWH followed up the HIV/AIDS outpatient Istanbul/Turkey. Methods A cross-sectional study was conducted at of Infectious Diseases (ID) departments hospitals affiliated ACTHIV-IST Study Group. Structured interviews were performed using questionnaires that covered...

10.1177/09564624241301491 article EN International Journal of STD & AIDS 2024-11-19

Introduction Prejudice, stigmatization and discrimination behaviors causes social stress lead vulnerability to mental physical health problems in Transgender Gender Nonconforming (TGNC) individuals. The prevalence of disorders that can be associated with “minority group stress”, especially major depression anxiety disorders, are known higher the TGNC comparison general population. Objectives aim this study was reveal impact minority on individuals’ health. Resilience factors like gender...

10.1192/j.eurpsy.2021.1620 article EN cc-by-nc-nd European Psychiatry 2021-04-01

It is shown that the language process abilities such as verbal fluency and confrontational naming are deteriorated in Alzheimer's disease (AD). noted particular affected early stages whereas distorted later stages. Our hypothesis deterioration ability more related with decline semantic than phonemic AD patient. Language a network process, therefore it can be stated disruptions show themselves every area connected language. So, function, categoric should same level lexical fluency. The aim of...

10.1016/j.jalz.2014.05.1679 article EN Alzheimer s & Dementia 2014-07-01

Objective: Obstructive sleep apnea (OSA) is known to have disruptive effects on cognitive functions (CFs) in advanced ages.The aim of this study was reveal the effect(s) Continuous Positive Airway Pressure (CPAP) treatment CFs older patients with OSA.Materials and Methods: Follow-up comparisons were conducted after 6 months CPAP Pulmonary Medicine Department's outpatient clinic a reference university hospital.Patients included one-night hospitalization for polysomnographic assessments.All...

10.4274/ejgg.galenos.2023.2023-1-2 article EN European Journal of Geriatrics and Gerontology 2023-07-10

In this study, we aimed to examine the relationship between decision-making processes and other cognitive characteristics associated with Borderline Personality Disorder (BPD) in comparison healthy controls by using neurocognitive tests.

10.29399/npa.28439 article EN Nöro Psikiyatri Arşivi 2023-01-01

Transgender and Gender Non-Conforming (TGNC) individuals experience stress due to discriminatory events in society. This causes them become vulnerable physical mental health problems. However, there is no validated scale that can be used the assessment of TGNC people counseling Turkey. Minority Stress Resilience Measure (GMSR) a evaluates resilience factors individuals. The aim this study investigate validity Turkish version GMSR (GMSR-Tr). Our presents preliminary evidence GMSR-Tr.

10.1080/26924951.2023.2202353 article EN Journal of LGBTQ Issues in Counseling 2023-10-31

10.1016/j.nsa.2023.103369 article EN cc-by-nc-nd Neuroscience Applied 2023-01-01

Photograph was used as a therapeutic tool for the first time in 1856 by Dr. Hugh Diamond. Photos are considered to be representations of person's reality. The possibility producing visual images when client has verbal expression difficulties, photography provides more structured way expressing ideas and emotions means projective-symbolic communication. Photo therapy with chronic psychotic patients may contribute development perception reality, part-whole relationship, integration,...

10.1016/j.eurpsy.2017.01.1464 article EN European Psychiatry 2017-04-01

Apathy is a behavioral executive dysfunction roughly described with loss of motivation and interest, reduced initiation social interaction, poor persistence, indifference superficial emotional reactions. Alzheimer's Disease (AD) patients apathy show higher functional deterioration. We assume that frontal lobe hypofunction apathetic AD (aAD) are more apparent than the without apathy. The aim this study to address neuroanatomical correlates in early stage AD. Sample was gathered from Neurology...

10.1016/j.jalz.2017.06.1060 article EN Alzheimer s & Dementia 2017-07-01

Apathy described as a behavioral executive disfunction, roughly with loss of motivation and interest, reduced initiation social interaction, poor persistence, indifference insight. Comorbid psychiatric diagnosis is significant determinant for prognosis. AD patients apathy show higher functional deterioration than without apathy. We assume that frontal lobe hypofunction apathetic (aAD) are more apparent the Sample group recruited from Neurology Geriatric Psychiatry Departments Istanbul...

10.1016/j.jalz.2018.06.324 article EN Alzheimer s & Dementia 2018-07-01
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