A5025970998- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Protein Structure and Dynamics
- Pulmonary Hypertension Research and Treatments
- Kawasaki Disease and Coronary Complications
- Sarcoma Diagnosis and Treatment
- Cardiovascular Issues in Pregnancy
- Pancreatic function and diabetes
- Cardiovascular Effects of Exercise
- Vector-borne infectious diseases
- Advanced MRI Techniques and Applications
- Cancer, Lipids, and Metabolism
- Nutrition and Health in Aging
- Folate and B Vitamins Research
- Diabetes Management and Research
- Aortic Disease and Treatment Approaches
- Cardiac tumors and thrombi
SUNY Downstate Health Sciences University
2022-2024
State University of New York
2024
Harvard University
2014
Duke Medical Center
2012
University of Michigan
2010
Protein sequences encode both structure and foldability. Whereas the interrelationship of sequence has been extensively investigated, origins folding efficiency are enigmatic. We demonstrate that proinsulin requires a flexible N-terminal hydrophobic residue is dispensable for structure, activity, stability mature hormone. This (PheB1 in placental mammals) variably positioned within crystal structures exhibits 1H NMR motional narrowing solution. Despite such flexibility, its deletion impaired...
A 43-year-old man with an unremarkable medical history presented to our hospital 2 weeks of headaches, ataxia and confusion. CT the head revealed a large haemorrhagic cystic lesion. subsequent chest left atrial mass. The mass was subsequently biopsied positive immunohistochemistry staining for MDM2, FLI1 vimentin. Real-time PCR MDM2 amplification, confirming diagnosis intimal sarcoma. patient underwent surgical resection reconstruction atrium discharge short-term rehabilitation, but his...
Acute Coronary Syndrome and decompensated Heart Failure can present with a similar symptoms cn be difficult to differentiate. This study assesses correlation between the BNP/Troponin ratio presence of obstructive coronary artery disease on cardiac catheterization. A Single-center retrospective patients who were presented Emergency Department (ED) suspicious acute syndrome (ACS). Peak BNP hsTrop ratios (BNP/hsTrop) recorded. Cardiac Catheterisation findings during admission The predictive...
Introduction: The utility of pre-procedure statins prior to coronary angiography has been utilized as an adjunct in the prevention contrast-induced nephropathy (CIN). This attributed pleotropic and anti-inflammatory effects statin. Whether there is a dose intensity dependent effect on CIN unknown. Methods: We performed hierarchical network meta-analysis all published randomized-controlled trials up March 2020 determine whether high-intensity atorvastatin (40mg or 80mg) was superior lower...
Introduction: Heart Failure is one of the leading causes readmission in United States. with preserved Ejection Fraction (HFpEF) accounts for a growing proportion heart failure hospitalizations and approximately half today. Unlike reduced (HFrEF), there are no consensus-driven guidelines management HFpEF. Methods: We collected demographic data, co-morbidities, laboratory echocardiographic data on patients hospitalized HFpEF throughout our health care system between August 2016 to 2017....
Background: The H2FPEF score is a validated scoring system to determine whether dyspnea may be due heart failure with preserved ejection fraction (HFpEF). Recent evidence has suggested that correlate outcomes in established HFpEF. Its utilization for estimating mortality patients who die within one year of discharge not known. Methods: We collected clinical demographics and echocardiographic parameters from reports calculate scores 301 admitted decompensated HFpEF between August 2016 2017....
Introduction: Acute Decompensated Heart Failure is one of the most common reasons for hospitalization in United States. failure with preserved ejection fraction (HFpEF) accounts nearly half all heart admissions, significant contribution owing to various co-morbidities. The role kidney impairment on admission and prognostic association early HFpEF readmission unclear. Methods: We conducted a retrospective analysis patients admitted decompensated at hospital New York City. Clinical...