A5037960497- Antibiotic Resistance in Bacteria
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Use and Resistance
- Infectious Diseases and Tuberculosis
- Cerebrospinal fluid and hydrocephalus
- Pharmaceutical Practices and Patient Outcomes
- Bacterial Infections and Vaccines
- SARS-CoV-2 and COVID-19 Research
- Antimicrobial Resistance in Staphylococcus
- Pharmaceutical studies and practices
- Pharmacovigilance and Adverse Drug Reactions
- COVID-19 Clinical Research Studies
- Health and Medical Education
- Orthopedic Infections and Treatments
- Patient Satisfaction in Healthcare
- Pneumonia and Respiratory Infections
- Urinary Tract Infections Management
- Health Literacy and Information Accessibility
- Biosimilars and Bioanalytical Methods
- Pharmacological Receptor Mechanisms and Effects
- Infective Endocarditis Diagnosis and Management
- Bacterial Identification and Susceptibility Testing
- Vibrio bacteria research studies
- Emergency and Acute Care Studies
- Patient Safety and Medication Errors
University Hospital Complex Of Vigo
2008-2023
Complexo Hospitalario Universitario A Coruña
2008-2023
Experience in real clinical practice with ceftazidime/avibactam is limited, and there are even fewer data on infections due to OXA-48-producing Enterobacteriaceae. We designed an observational study of a prospectively collected cohort adult patients receiving our centre. Only the first treatment course each patient was analysed. Efficacy safety were evaluated as 14 30 day mortality, recurrence rate at 90 days, resistance development occurrence adverse effects. Fifty-seven treated...
Due to its long half-life, dalbavancin offers benefits for long-duration treatments, especially osteoarticular and infective endocarditis (IE). We evaluated the efficacy costs of IE treatment, comparing with standard care (SOC).Retrospective multicenter cohort study adult patients Gram-positive cocci definite IE. Dalbavancin was used as a sequential therapy before discharge. Efficacy combined variable clinical cure absence recurrence in 12-month follow-up. Length hospital stay associated...
Carbapenems (CR) have traditionally been the first line treatment for bacteremia caused by AmpC-producing Enterobacterales. However, CR a high ecological impact, and carbapenem-resistant strains continue rising. Thus, other alternatives like Piperacillin-Tazobactam (P-T) or Cefepime (CEF) oral sequential therapy (OST) are being evaluated.We conducted retrospective, single-centre observational study. All adult patients with Enterobacterales were included. The primary endpoint was clinical...
What is known and objective Initial treatment recommendations of COVID-19 were based on the use antimicrobial drugs immunomodulators. Although information drug interactions was available for other pathologies, there little evidence in COVID-19. The this study to analyse potential drug-drug (pDDIs) derived from medication used patients first pandemic wave evaluate real consequences such clinical practice. Methods Cohort, retrospective single-centre carried out a third-level hospital. Adult...
Abstract Carbapenemase-producing Enterobacterales constitute a serious public health threat; however, information on the oxacilinasa (OXA-48)-type is limited. The objective of study was to evaluate risk factors associated with 14-day mortality for patients bacteremia due OXA-48 carbapenemase-producing Klebsiella pneumoniae . We conducted retrospective, single-center observational adult K. bacteremia, classifying strains as carbapenem-susceptible (CSKp) and carbapenem-resistant (CRKp). All...
The incidence of adverse effects in hospitals is very high and a lot them are related to medication. most important factor pharmaceutical interventions reduce medication reconciliation, this process indispensable during hospital care. Reasons for reconciliation errors numerous but high-rotation care unit, such as emergency department short stay units (SSUs) more hazardous areas patient safety. Prospective observational study was performed 3 months. Medication pharmacotherapeutic were carried...
<h3>Background</h3> The emergency medicine (EM) pharmacist, on working days, performs medication review and reconciliation. EM pharmacist communicates, verbally or through small reports, the interventions to doctor. After electronic prescription (EP) implementation, in October 2017, these reports changed a messaging system of programme. <h3>Purpose</h3> To analyse impact EP interventions. <h3>Material methods</h3> Unicentric, observational prospective study conducted tertiary university...
<h3>Background</h3> An empirical antibiotic treatment guide (EATG) was implemented in our hospital January 2017. This developed by the antimicrobial stewardship team, composed of infectious disease specialists, microbiologists and pharmacists. The aim to optimize prescription, avoiding use antibiotics associated with resistance development, such as quinolones, third-generation cephalosporins carbapenems.<sup>1,2</sup> <h3>Purpose</h3> To evaluate changes consumption their costs, after EATG...