- Antibiotic Resistance in Bacteria
- Infective Endocarditis Diagnosis and Management
- Brazilian Legal Issues
- Antibiotics Pharmacokinetics and Efficacy
- Trypanosoma species research and implications
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Infectious Aortic and Vascular Conditions
- Long-Term Effects of COVID-19
- Antibiotic Use and Resistance
- COVID-19 Clinical Research Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Education Pedagogy and Practices
- Biliary and Gastrointestinal Fistulas
- Business and Management Studies
- Systemic Lupus Erythematosus Research
- Education and Digital Technologies
- Streptococcal Infections and Treatments
- Gallbladder and Bile Duct Disorders
- Law, Economics, and Judicial Systems
- Cardiac Valve Diseases and Treatments
- Rural Development and Agriculture
- Youth, Politics, and Society
- Green IT and Sustainability
- Medical Malpractice and Liability Issues
University Hospital Complex Of Vigo
2019-2024
Complexo Hospitalario Universitario A Coruña
2022-2024
Galicia Sur Biomedical Foundation
2022-2024
Complejo Hospitalario de Pontevedra
2024
Servicio Gallego de Salud
2022-2023
Due to its long half-life, dalbavancin offers benefits for long-duration treatments, especially osteoarticular and infective endocarditis (IE). We evaluated the efficacy costs of IE treatment, comparing with standard care (SOC).Retrospective multicenter cohort study adult patients Gram-positive cocci definite IE. Dalbavancin was used as a sequential therapy before discharge. Efficacy combined variable clinical cure absence recurrence in 12-month follow-up. Length hospital stay associated...
Treatment optimization for serious infections, such as Staphylococcus aureus bacteremia (SAB), is a challenge antimicrobial stewardship teams. Currently, SAB guidelines recommend completely intravenous therapy (CIT).The objective of the study was to analyze usefulness and safety oral sequential (OST) in SAB.We conducted retrospective, observational tertiary teaching hospital Spain. The inclusion criteria were complicated non-complicated monomicrobial an adequate duration therapy, with...
Carbapenems (CR) have traditionally been the first line treatment for bacteremia caused by AmpC-producing Enterobacterales. However, CR a high ecological impact, and carbapenem-resistant strains continue rising. Thus, other alternatives like Piperacillin-Tazobactam (P-T) or Cefepime (CEF) oral sequential therapy (OST) are being evaluated.We conducted retrospective, single-centre observational study. All adult patients with Enterobacterales were included. The primary endpoint was clinical...
Community-onset bloodstream infections (CO-BSI) caused by gram-negative bacilli are common and associated with significant mortality; those Pseudomonas aeruginosa worse prognosis higher rates of inadequateempirical antibiotic treatment. The aims this study were to describe the characteristics patients CO-BSI P. aeruginosa, identify predictors, develop a predictive score for CO-BSI. Materials/methods: PROBAC is prospective cohort including >14 years BSI from 26 Spanish hospitals between...
Corticosteroids are the most important factor to reduce mortality in patients with moderate-severe COVID-19. The aim of study was analyze impact methylprednisolone pulse (MPP) on in-hospital acute respiratory distress syndrome (ARDS) due We conducted a retrospective, single-center observational selected adult admitted hospital diagnosis COVID-19 between March and June 2020. A total 306 were analyzed. In-hospital crude rate 17%. Diabetes mellitus (HR 5.5, 95% CI 1.40–4.55), dementia 7.7,...
Objective NLRP3 mosaicism is a well-established mechanism causing cryopyrin-associated periodic syndromes (CAPS). The number of reported patients with small, and the knowledge about long-term disease behavior limited. Herein we have assembled largest cohort individuals to date obtain additional evidence that strengthens understanding this disease. Methods Patients data were collected from their medical charts. Genetic analyses performed using Sanger next-generation sequencing. In vitro...
Positron emission tomography (