- Antibiotic Resistance in Bacteria
- Infective Endocarditis Diagnosis and Management
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Streptococcal Infections and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial Resistance in Staphylococcus
- SARS-CoV-2 and COVID-19 Research
- Nosocomial Infections in ICU
- SARS-CoV-2 detection and testing
- Pneumonia and Respiratory Infections
- Oral microbiology and periodontitis research
- Biosensors and Analytical Detection
- Gallbladder and Bile Duct Disorders
- Antifungal resistance and susceptibility
- Central Venous Catheters and Hemodialysis
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Pediatric Hepatobiliary Diseases and Treatments
- Bacterial biofilms and quorum sensing
- Urinary Tract Infections Management
- Enterobacteriaceae and Cronobacter Research
- Biliary and Gastrointestinal Fistulas
- Vibrio bacteria research studies
University Hospital Complex Of Vigo
2015-2024
Galicia Sur Biomedical Foundation
2020-2024
Complexo Hospitalario Universitario A Coruña
2011-2024
Servicio Gallego de Salud
2020-2023
Universidade de Vigo
2020-2021
Biomedical Research Institute
2021
Microbiology Society
2021
Colciencias
2018
Complejo Hospitalario Universitario de Santiago
2008-2011
Universidade de Santiago de Compostela
2009-2010
SARS-CoV-2 genetic material is detectable in the faeces of a considerable part COVID-19 cases and hence, municipal wastewater. This fact was confirmed early during spread pandemic prompted several studies that proposed monitoring its incidence by paper fate wastewater treatment plants using RT-qPCR with two-fold goal: i) to check presence water effluent produced sludge ii) based on understanding virus particles fate, identify most suitable spots for detecting monitor evolution. On grounds...
Experience in real clinical practice with ceftazidime/avibactam is limited, and there are even fewer data on infections due to OXA-48-producing Enterobacteriaceae. We designed an observational study of a prospectively collected cohort adult patients receiving our centre. Only the first treatment course each patient was analysed. Efficacy safety were evaluated as 14 30 day mortality, recurrence rate at 90 days, resistance development occurrence adverse effects. Fifty-seven treated...
A bstract SARS-CoV-2 genetic material is detectable in the faeces of a considerable part COVID-19 cases and hence, urban wastewater. This fact was confirmed early during spread pandemic prompted several studies that proposed monitoring its incidence by paper fate wastewater treatment plants using RT-qPCR with two-fold goal: i) to check safety water effluent also sludge produced ii) based on understanding virus particles fate, identify most suitable spots for detecting monitor evolution. On...
Due to its long half-life, dalbavancin offers benefits for long-duration treatments, especially osteoarticular and infective endocarditis (IE). We evaluated the efficacy costs of IE treatment, comparing with standard care (SOC).Retrospective multicenter cohort study adult patients Gram-positive cocci definite IE. Dalbavancin was used as a sequential therapy before discharge. Efficacy combined variable clinical cure absence recurrence in 12-month follow-up. Length hospital stay associated...
Sepsis is one of the leading causes morbidity and mortality in hospitalized patients worldwide. Molecular technologies for rapid detection microorganisms with sepsis have only recently become available. LightCycler SeptiFast test M(grade) (Roche Diagnostics GmbH) a multiplex PCR analysis able to detect DNA 25 most frequent pathogens bloodstream infections. The time labor saved while avoiding excessive laboratory manipulation rationale selecting automated MagNA Pure compact nucleic acid...
Nosocomial infections caused by multidrug-resistant and carbapenem-resistant Pseudomonas putida isolates have been reported occasionally in severely ill or immunocompromised patients. Here we report the microbiological characteristics of what are believed to be two first VIM metallo-beta-lactamase (MBL)-producing P. strains Spain, which were isolated from patients at University Hospital Complex Santiago de Compostela. Both with severe underlying diseases had hospitalized for more than 15...
Some evidence-based bundles have tried to standardize the management of Staphylococcus aureus bacteraemia (SAB) improve outcome. The aim our study was analyse additional impact on mortality a structured intervention in patients with SAB.Compliance bundle evaluated an ambispective cohort SAB, which included retrospective [including treated before and after implementation programme (no-BP BP, respectively)] prospective (i-BP), specific for application implemented. Multivariate logistic...
A new α-haemolytic streptococcal strain has been isolated from the dental plaque of a teenager with Down syndrome. Genetic and taxonomic analyses place this Streptococcus within oralis group. It is Gram-stain-positive, non-motile, non-spore-forming spherical alpha-haemolytic coccus arranged in chains, it ferments large number monosaccharides disaccharides, as well polymeric carbohydrates. differs biochemically closely related species due to its production α-galactosidase, β-galactosidase...
Abstract Carbapenemase-producing Enterobacterales constitute a serious public health threat; however, information on the oxacilinasa (OXA-48)-type is limited. The objective of study was to evaluate risk factors associated with 14-day mortality for patients bacteremia due OXA-48 carbapenemase-producing Klebsiella pneumoniae . We conducted retrospective, single-center observational adult K. bacteremia, classifying strains as carbapenem-susceptible (CSKp) and carbapenem-resistant (CRKp). All...
Carbapenems (CR) have traditionally been the first line treatment for bacteremia caused by AmpC-producing Enterobacterales. However, CR a high ecological impact, and carbapenem-resistant strains continue rising. Thus, other alternatives like Piperacillin-Tazobactam (P-T) or Cefepime (CEF) oral sequential therapy (OST) are being evaluated.We conducted retrospective, single-centre observational study. All adult patients with Enterobacterales were included. The primary endpoint was clinical...
Background: In recent years, several scores and algorithms have been developed in order to guide empirical antibiotic treatment patients with gram-negative bacilli (GNB) bacteraemia according the risk of extended-spectrum β-lactamase (BL) producing. Some these do not easy applicability or present some limitations their validation. The aim our study was validate a recently designed decision tree prospective cohort due bacilli.Methods: We prospectively identified analyzed all adult centre...
ABSTRACT Workers and residents in Care Homes are considered at special risk for the acquisition of SARS-CoV-2 infection, due to infectivity high mortality rate case residents, compared other containment areas. The aims present study, based our local experience, were (a) describe prevalence institutionalized people Galicia (Spain) during Coronavirus pandemic (b) evaluate expected performance a pooling strategy using RT-PCR next rounds screening people. Distribution infection Houses was...