A5027013473- Neurogenesis and neuroplasticity mechanisms
- Axon Guidance and Neuronal Signaling
- Prion Diseases and Protein Misfolding
- Neuroscience and Neural Engineering
- Selenium in Biological Systems
- Environmental Toxicology and Ecotoxicology
- Neurological diseases and metabolism
- 3D Printing in Biomedical Research
- Nerve injury and regeneration
- Nanoparticles: synthesis and applications
- Nuclear Receptors and Signaling
- Cellular Mechanics and Interactions
- Genetic Neurodegenerative Diseases
- Neuroscience and Neuropharmacology Research
- Alzheimer's disease research and treatments
Universitat de Barcelona
2015-2022
Biomedical Research Networking Center on Neurodegenerative Diseases
2020-2022
Instituto de Salud Carlos III
2021-2022
Institute for Bioengineering of Catalonia
2015-2022
The cellular prion protein, encoded by the gene Prnp, has been reported to be a receptor of β-amyloid. Their interaction is mandatory for neurotoxic effects β-amyloid oligomers. In this study, we aimed explore whether protein participates in spreading α-synuclein. Results demonstrate that Prnp expression not α-synuclein spreading. However, although pathological can take place absence expanded faster PrPC-overexpressing mice. addition, binds strongly on PrPC-expressing cells, suggesting role...
We have presented here a simple microfluidic approach to model mechanical and synchronized axotomy of large number axons study axonal regeneration, facilitate rapid screening discovery novel pharmaceutical compounds.
Emerging evidence points to coordinated action of chemical and mechanical cues during brain development. At early stages neocortical development, angiogenic factors chemokines such as CXCL12, ephrins, semaphorins assume crucial roles in orchestrating neuronal migration axon elongation postmitotic neurons. Here we explore the intrinsic properties developing marginal zone pallium migratory pathways distribution pioneer Cajal-Retzius cells. These neurons are generated several proliferative...
Abstract Emerging evidence points to coordinated action of chemical and mechanical cues during brain development. At early stages neocortical development, angiogenic factors chemokines such as CXCL12, ephrins, semaphorins assume crucial roles in orchestrating neuronal migration axon elongation postmitotic neurons. Here we explore the intrinsic properties developing marginal zone pallium migratory pathways distribution pioneer Cajal-Retzius cells. These neurons are generated several...