A5009154201- Acute Ischemic Stroke Management
- Epilepsy research and treatment
- Cardiac Arrest and Resuscitation
- Pharmacological Effects and Toxicity Studies
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Neurological Complications and Syndromes
- Autoimmune Neurological Disorders and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebral Venous Sinus Thrombosis
- Thermal Regulation in Medicine
- Heart Rate Variability and Autonomic Control
- Infective Endocarditis Diagnosis and Management
- Otolaryngology and Infectious Diseases
- Amino Acid Enzymes and Metabolism
- Long-Term Effects of COVID-19
- EEG and Brain-Computer Interfaces
- Venous Thromboembolism Diagnosis and Management
- Multiple Sclerosis Research Studies
- Moyamoya disease diagnosis and treatment
- Tuberculosis Research and Epidemiology
- Takotsubo Cardiomyopathy and Associated Phenomena
- Peripheral Neuropathies and Disorders
Boston Medical Center
2020-2025
Boston University
2021-2025
University Medical Center
2023
University School
2021
Wayne State University
2013-2019
Detroit Medical Center
2015-2019
New School
1963
Objectives Animal studies have suggested that valproic acid (VPA) is neuroprotective in aneurysmal subarachnoid hemorrhage (SAH). However, the effect of VPA on SAH outcomes humans has not been investigated. Methods We conducted a retrospective analysis 123 patients with nontraumatic SAH. Eighty-seven had an source and 36 no culprit lesion identified. used stepwise logistic regression to determine association between delayed cerebral ischemia (DCI), radiographic vasospasm, discharge modified...
Reversible cerebral vasoconstriction syndrome (RCVS) is increasingly being recognized as a diagnosis in patients presenting with thunderclap headaches. In the vast majority of cases, follows benign course and recover completely without any significant therapeutic intervention. rarest RCVS monophasic rapid worsening, severe neurological deficits, poor outcomes. We present case 25-year-old female who presented headaches which were worsening over 1 week. She was admitted to hospital rapidly...
Nothing to report.
Eye movement quantification in polysomnograms (PSG) is difficult and resource intensive. Automated eye detection would enable further study of patterns normal abnormal sleep, which could be clinically diagnostic neurologic disorders, or used to monitor potential treatments. We trained a long short-term memory (LSTM) algorithm that can identify occurrence with high sensitivity specificity. conducted retrospective, single-center using one-hour PSG samples from 47 patients 18-90 years age. Team...
Animal studies have suggested that valproic acid (VPA) is neuroprotective in aneurysmal subarachnoid hemorrhage (SAH). Potential mechanisms include an effect on cortical spreading depolarizations (CSD), apoptosis, blood-brain barrier integrity, and inflammatory pathways. However, the of VPA SAH outcomes humans has not been investigated.
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Cerebral infections have been reported after endovascular interventions such as embolization and coiling. Such complications are extremely rare only one other case has in a patient who underwent an therapy for ischemic stroke. We report 32-year-old woman, presented to our hospital with headaches lasting four weeks intervention stroke via mechanical thrombectomy. Further investigations revealed cerebral abscess the area of infarct. She was effectively treated antibiotics combination...
OBJECTIVE: We define early predictors of poor neurological outcome in post cardiac arrest (CA) patients undergoing hypothermia therapy. BACKGROUND: There are few tools available for clinicians to predict outcomes CA survivors. Adequate, risk-stratification would be helpful terms clinical care and resource utilization. DESIGN/METHODS: 350 charts from 2009-2013 were reviewed retrospectively. Demographics including patient9s age, gender, medical comorbidities as well rhythm, downtime...
Electrocardiogram (ECG) changes suggestive of cardiac ischemia are frequently demonstrated in patients with ischemic stroke and subarachnoid hemorrhage. However, little is known such particularly acute ST segment myocardial infarction (STEMI) intracerebral hemorrhage (ICH), especially after neurosurgery. We present a patient intraparenchymal due to cerebral arteriovenous malformation (AVM) who exhibited STEMI Serial biomarkers echocardiograms were performed which did not reveal any evidence...
The objective of this case report was to describe a rare presentation corkscrew cerebral angiopathy presenting as subarachnoid hemorrhage (SAH).We present young woman who presented with thunderclap headache, found have nonaneurysmal SAH.Cerebral angiogram revealed in medium-sized vessels and multiple micro-occlusions collateralization. No intracranial aneurysm detected. Extensive workup for vasculitis genetic causes vasculopathy unrevealing. patient had no neurologic deficits, her symptoms...
OBJECTIVE: To evaluate which EEG patterns are associated with poor outcomes in post-cardiac arrest (PCA) patients treated hypothermia. BACKGROUND: Therapeutic hypothermia (TH) has been proven to improve neurological outcome survivors of cardiac arrest. However few studies have reported prognostication using continuous monitoring during METHODS: Retrospective chart review between July 2009 through April 2013 was completed all Hypothermia PCA and initiated TH achieved a standard protocol at...
OBJECTIVE:To determine which scale best predicts the outcome of SAH among H&H, GCS and Fischer grade, independent demographic risk factors BACKGROUND:Multiple grading scales have been developed to grade severity subarachonid haemorrhage(SAH). The most widely used scales, Hunt Hess(H&H), Glasgow Coma Scale(GCS were based on symptoms,which has resulted in unclear correlation with outcome. DESIGN/METHODS:A retrospective chart review 141 consecutive patients who presented 2 academic institutions...
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Objective: Lacosamide can be used as an earlier anti-epileptic drug (AED) in the management of status epilepticus (SE). Background: The gold standard treatment SE is a benzodiazepine followed by first generation AED. Lacosamide's efficacy termination limited to small case series. Methods: We performed single-center, retrospective chart review 117 consecutive patients admitted for who received lacosamide from 2011-2014. gathered baseline characteristics, time and order AEDs given until was...
OBJECTIVE: A case report describing an atypical presentation of Posterior Reversible Encephalopathy Syndrome (PRES). BACKGROUND: PRES is a rare, potentially life threatening, central nervous system disorder, typically presenting as acute onset headache, change in mental status, visual symptoms, seizures or focal neurological deficits. High level suspicion from clinical and neuro-radiological findings essential for early diagnosis which vital effective management. DESIGN: Case report....