A5072412319- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Long-Term Effects of COVID-19
- Autoimmune Neurological Disorders and Treatments
- Clinical Reasoning and Diagnostic Skills
- Infectious Encephalopathies and Encephalitis
- Cerebrospinal fluid and hydrocephalus
- Trauma and Emergency Care Studies
- Bacterial Infections and Vaccines
- Neurological Complications and Syndromes
- Neurosurgical Procedures and Complications
- COVID-19 and healthcare impacts
- Organ Donation and Transplantation
- COVID-19 Clinical Research Studies
- Cerebrovascular and Carotid Artery Diseases
- Infectious Diseases and Tuberculosis
- Neurological and metabolic disorders
- Machine Learning in Healthcare
- Infective Endocarditis Diagnosis and Management
- Palliative Care and End-of-Life Issues
- Gun Ownership and Violence Research
- Takotsubo Cardiomyopathy and Associated Phenomena
- HIV Research and Treatment
- Artificial Intelligence in Healthcare and Education
Boston Medical Center
2018-2023
University Medical Center
2020-2023
Boston University
2018-2023
NYU Langone Health
2023
University of Kansas Medical Center
2023
University of Pennsylvania
2023
E Ink (South Korea)
2021
University School
2020
Oregon Health & Science University
2012-2015
Portland VA Medical Center
2014
Worldwide, there are nearly 10 million new cases of dementia annually, which Alzheimer's disease (AD) is the most common. New measures needed to improve diagnosis individuals with cognitive impairment due various etiologies. Here, we report a deep learning framework that accomplishes multiple diagnostic steps in successive fashion identify persons normal cognition (NC), mild (MCI), AD, and non-AD dementias (nADD). We demonstrate range models capable accepting flexible combinations routinely...
The purpose of this guideline is to update the 2010 American Academy Neurology (AAN) brain death/death by neurologic criteria (BD/DNC) for adults and 2011 Pediatrics, Child Society, Society Critical Care Medicine infants children clarify BD/DNC determination process integrating guidance into a single guideline. Updates in include related conducting evaluation context extracorporeal membrane oxygenation, targeted temperature management, primary infratentorial injury.
RCVS (Reversible Cerebral Vasoconstrictive Syndrome) is a condition associated with vasoactive agents that alter endothelial function. There growing evidence inflammation contributes to cerebrovascular disease in patients coronavirus 2019 (COVID-19). In our study, we describe the clinical features, risk factors, and outcomes of multicenter case series COVID-19.Multicenter retrospective series. We collected characteristics, imaging, COVID-19 identified at each participating site.Ten were...
Background Survivors of intracranial hemorrhage (ICH) are at increased risk for major adverse cardiovascular and cerebrovascular events (MACCE), in the form recurrent stroke myocardial Infarction. We investigated whether long-term blood pressure (BP) variability represents a factor MACCE after ICH, independent average BP. Methods Results analyzed data from prospective ICH cohort studies Massachusetts General Hospital University Hong Kong. captured (ie, visit-to-visit) BP variability,...
Background and purpose The diagnosis management of acute fetal posterior cerebral artery occlusion are challenging. While endovascular treatment is established for anterior circulation large vessel stroke, little known about the course occlusions. We report clinical course, radiological findings considerations stroke. Methods performed a retrospective review consecutive patients presenting with who underwent angiogram and/or mechanical thrombectomy between January 2015 2021. Patients...
To determine the incidence of acute neuroimaging (NI) findings and comorbidities in coronavirus disease 2019 (COVID-19)-infected subjects seven U.S. four European hospitals.This is a retrospective study COVID-19-positive with following inclusion criteria: age >18, lab-confirmed COVID-19 infection, NI (NI+) attributed to on CT or MRI brain. NI+ total hospitalized (TN) were assessed.A 37,950 reviewed 4342 underwent NI. was 10.1% (442/4342) including 7.9% (294/3701) United States 22.8%...
Nothing to report.
Perihematomal edema (PHE) surrounding intracerebral hemorrhage (ICH) may contribute to disease-associated morbidity. Before quantifying PHE's effects on morbidity, a fast, accurate, and reproducible method for measuring PHE volume is needed. The aim of this study demonstrate the use semiautomated dual clustering segmentation algorithm generate volumetrics noncontrast computed tomography (CT) head compare technique physicians' manual calculations.This single-center, retrospective imaging that...
Objective Cumulative clinical, cellular, and molecular evidence reinforces the role of neutrophils in secondary brain injury spontaneous intracerebral hemorrhage (sICH). However, since generalized neutrophil inhibition is detrimental, identification targetable “rogue” subsets associated with sICH severity key. Methods In a pilot prospective observational study consented patients sICH, we immunotyped whole blood to assess circulating markers (~day 3 after ICH symptoms onset): (a) DEspR±CD11b±...
AbstractObjectives: This study tested the validity of Human Activity Profile (HAP) in an HIV-positive population receiving highly active antiretroviral therapy (HAART). The HAP is a 94-item questionnaire for estimating functional capacity based on estimated metabolic equivalents activities daily living. Methods: Twenty-six participants (24 male, 2 female; age 46.0 ± 9.3 years) HAART completed and exercise protocol (Balke treadmill test). yields maximal activity score (MAS) adjusted (AAS; MAS...
BACKGROUND: The emergence of neuroscience intensive care units (NSICUs) for the past decades has led to growing interest in targeted training NSICU nurses. We sought evaluate use video instruction on nurses' skills case presentations and neurological examinations, which timely advantages as an asynchronous distanced learning modality. METHODS: enrolled surgical unit nurses who took shifts at our institution. Participants were observed by a neurocritical attending physician presenting...
Medical errors are estimated to cause 7,000 deaths and cost 17-29 billion USD per year, but there is a lack of published real-world data on preventable errors, in particular hospital-based neurology. We sought characterize the profile that occur inpatient neurology services at our institution inform strategies future error prevention.We reviewed all cases occurring from July 1, 2018, June 30, 2020, logged institutional reporting systems departmental morbidity mortality conferences (M&MC)....
Background Multidetector CT (MDCT) enables rapid and accurate diagnosis of head neck (HN) injuries in patients with blunt trauma (BT). However, MDCT is overused, appropriate selection for imaging could improve workflow. Purpose To investigate the effect implementing clinical triaging algorithms on use HN who have sustained BT. Materials Methods In this retrospective study, aged 15 years or older BT admitted between October 28, 2007, December 31, 2013, were included. Patients divided into...
Introduction: Both Intraventricular hemorrhage (IVH) and fever after spontaneous intracranial (ICH) have been consistently associated with poor outcomes. Additionally, IVH is an independent risk factor for hemorrhagic stroke (ICH), but it not known if the degree of intraventricular predictive fever. We hypothesized that extent hemorrhage, defined by modified Graeb score, intensity Methods: performed a single center, retrospective review consecutively admitted adult patients ICH from April...
Neurologists may be confronted with patients who present inflammatory brain lesions where the diagnosis cannot made through history and physical examination alone. Molecular testing for bacterial infections, tuberculosis, fungal infections aid in diagnosis. Since treatments these disorders are different delays can result permanent neurologic disability death, rapid accurate diagnoses critical. This review provides neurologist options recommends ways to enhance sensitivity specificity.