A5044189710- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Spinal Dysraphism and Malformations
- Cerebral Palsy and Movement Disorders
- EEG and Brain-Computer Interfaces
- Traumatic Brain Injury Research
- MRI in cancer diagnosis
- Spinal Cord Injury Research
- Acute Ischemic Stroke Management
- Neurological disorders and treatments
- Musculoskeletal pain and rehabilitation
- Medical Image Segmentation Techniques
- Stroke Rehabilitation and Recovery
- Epilepsy research and treatment
- Medical Imaging and Analysis
- Cerebrovascular and Carotid Artery Diseases
- Face Recognition and Perception
- Atomic and Subatomic Physics Research
- Transcranial Magnetic Stimulation Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Neural dynamics and brain function
- Brain Tumor Detection and Classification
- Neonatal and fetal brain pathology
- Pain Management and Treatment
Thomas Jefferson University
2016-2025
Imaging Center
2016-2025
Temple University
2009-2025
University of Maryland, Baltimore
2025
Thomas Jefferson University Hospital
1993-2024
Providence Newberg Medical Center
2024
Neurological Surgery
2023
University of Southern California
2020-2023
Fujifilm (Japan)
2020
The University of Melbourne
2020
Abstract Accurate lesion segmentation is critical in stroke rehabilitation research for the quantification of burden and accurate image processing. Current automated methods T1-weighted (T1w) MRIs, commonly used research, lack accuracy reliability. Manual remains gold standard, but it time-consuming, subjective, requires neuroanatomical expertise. We previously released an open-source dataset T1w MRIs manually-segmented masks (ATLAS v1.2, N = 304) to encourage development better algorithms....
Functional outcomes after stroke are strongly related to focal injury measures. However, the role of global brain health is less clear. In this study, we examined impact age, a measure neurobiological aging derived from whole-brain structural neuroimaging, on poststroke outcomes, with focus sensorimotor performance. We hypothesized that more lesion damage would result in older which turn be associated poorer outcomes. Related, expected age mediate relationship between and Finally,...
Purpose: To examine the neural correlates during deception and truth telling by using a functional magnetic resonance (MR) imaging technique an ecologically valid task to compare results with those of standard polygraph examination. Materials Methods: All subjects gave written informed consent for this HIPAA-approved study, which was approved institutional review board Drexel University. Eleven healthy (five female six male subjects; mean age, 28.9 years) were randomly assigned group guilty...
Restraint theory has been used to model the process that produces binge eating. However, there is no satisfactory explanation for tendency of restrained eaters (REs) engage in counterregulatory eating, an ostensible analogue Using functional magnetic resonance imaging (fMRI), authors investigated brain activation normal weight REs (N = 9) and unrestrained (UREs; N 10) when fasted fed viewing pictures highly moderately palatable foods neutral objects. When foods, UREs showed widespread...
Magnetic resonance imaging (MRI) generates potent electromagnetic forces in the form of a static, gradient, or pulsed radiofrequency magnetic field that can result pacemaker malfunction. This report documents case rapid cardiac pacing during MRI patient with dual chamber pacemaker. Although mechanism is unclear, it was directly related to pulsing. We postulated lead acts as an antenna for energy interacts pacemaker's output circuit, thus, causing at cycle length representing multiple...
<h3>BACKGROUND AND PURPOSE:</h3> Recent studies suggest that pediatric subjects as old 8-years-of-age may have difficulty with the ISNCSCI examinations. Our aim was to investigate DTI parameters of healthy spinal cord in children noncervical IS for comparison SCI and prospectively evaluate reliability measures correlate obtained ISNCSCI. <h3>MATERIALS METHODS:</h3> Five controls thoracic lumbar 5 cervical were imaged twice by using a single-shot echo-planar diffusion-weighted sequence. Axial...
In Brief Study Design. The design was a nonexperimental, repeated measures design. Objective. To examine the reliability of diffusion tensor imaging (DTI) values pediatric cord and to compare DTI with obtained on clinical examination findings from conventional magnetic resonance (MRI). Summary Background Data. quantifies water molecules in directions parallel transverse plane neuronal axons. unique characteristic architecture spinal allows white matter potentially separate gray assess...
Mild traumatic brain injury (mTBI) is a major public health concern that can result in broad spectrum of short-term and long-term symptoms. Recently, machine learning (ML) algorithms have been used neuroscience research for diagnostics prognostic assessment disorders. The present study aimed to develop an automatic classifier distinguish patients suffering from chronic mTBI healthy controls (HCs) utilizing multilevel metrics resting-state functional magnetic resonance imaging (rs-fMRI)....
This study presents automated atlas-based magnetization transfer (MT) measurements of the typically developing pediatric cervical spinal cord (SC). We report normative MT ratio (MTR) values from whole white matter (WM) and WM tracts, examining variations with age, sex, height, weight. scans 33 healthy females (mean age = 12.8) 22 males 13.09) were acquired SC (C2-C7) using a 3.0 T MRI. Data processed Toolbox, segmented, registered to PAM50 template. Affine non-rigid transformations...
BACKGROUND AND OBJECTIVES: The efficacy of deep brain stimulation (DBS) relies on accurate electrode placement. Unfortunately, deviation poses a persistent problem, with most electrodes demonstrating some degree bending. Although such bending does not always result in target deviation, an estimated 3% to 8% patients still require revision surgery address suboptimal DBS may occur at mechanical tissue interfaces, denser internal capsule (IC) fibers being the likely factor. Based basic...
A growing number of research studies have explored the potential effects vagus nerve stimulation (VNS) on brain physiology as well clinical particularly related to stress and anxiety. However, there currently are limited showing functional changes during different frequencies laterality transcutaneous auricular VNS (TaVNS). In this study, we evaluated whether TaVNS alters connectivity in healthy controls. We hypothesized that would significantly alter areas involved with emotional processing...
INTRODUCTION: Glioma-induced brain network reorganization often leads to neurological deficits, which vary depending on tumor location. METHODS: Resting-state fMRI was conducted 32 patients, including 15 with left temporal lesions and 17 frontal glioma. Group independent component analysis (ICA) employed extract networks, excluding tumor-affected areas, followed by dFC using the sliding window method k-means clustering. A two-sample t-test compared between speech-deficit normal speech...
Background Chronic pelvic pain is a substantial clinical challenge that profoundly impacts quality of life for many women. The Neuro Emotional Technique (NET) novel mind-body intervention designed to attenuate emotional arousal distressing thoughts and pain. This study evaluated functional connectivity changes in key areas the brain patients with chronic receiving NET intervention. goal was assess whether associated (FC) related reductions distress pain, particularly limbic areas,...
Spinal cord injury (SCI) in the pediatric population presents a unique challenge diagnosis and prognosis due to complexity of performing clinical assessments on children. Accurate evaluation structural changes spinal is essential for effective treatment planning. This study aims evaluate characteristics patients with SCI by comparing cross-sectional area (CSA), anterior-posterior (AP) width, right-left (RL) width across all vertebral levels between typically developing (TD) participants SCI....
<h3>BACKGROUND AND PURPOSE:</h3> DTI in the brain has been well established, but its application spinal cord, especially pediatrics, poses several challenges. The small cord size inherent low SNR of diffusion signal intensity, respiratory and cardiac movements induce artifacts, EPI sequences used for obtaining indices cause eddy-current distortions. purpose this study was to 1) evaluate accuracy cervical children using a newly developed iFOV sequence with spatially selective 2D-RF...