A5000320161- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Functional Brain Connectivity Studies
- Cerebrospinal fluid and hydrocephalus
- Dementia and Cognitive Impairment Research
- Traumatic Brain Injury Research
- Acute Ischemic Stroke Management
- Cardiovascular Health and Disease Prevention
- Long-Term Effects of COVID-19
- Advanced Neuroimaging Techniques and Applications
- Stroke Rehabilitation and Recovery
- Neurosurgical Procedures and Complications
- COVID-19 and Mental Health
- Spinal Dysraphism and Malformations
- Advanced MRI Techniques and Applications
- Intensive Care Unit Cognitive Disorders
- Fetal and Pediatric Neurological Disorders
- Neonatal and fetal brain pathology
- Physical Activity and Health
- Olfactory and Sensory Function Studies
- Epilepsy research and treatment
- Attention Deficit Hyperactivity Disorder
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Cardiac Arrest and Resuscitation
Universitat de Barcelona
2015-2025
Red de Investigación en Actividades Preventivas y Promoción de la Salud
2025
Sant Joan de Déu Research Foundation
2020-2024
Institut de Recerca Sant Joan de Déu
2020-2024
Hospital Clínico Universitario Virgen de la Victoria
2024
Imaging Center
2023
University of Southern California
2023
Hospital Sant Joan de Déu Barcelona
2019-2022
University of Bristol
2016-2017
Southmead Hospital
2016
Abstract Introduction Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack consensus on diagnosis, reflecting the use multiple different assessment protocols. A large multinational group clinicians researchers participated a two‐phase Vascular Impairment Cognition Classification Consensus Study (VICCCS) to agree principles (VICCCS‐1) protocols (VICCCS‐2) for diagnosis VCI. We present VICCCS‐2. Methods used VICCCS‐1 published diagnostic...
Abstract Introduction Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none been universally accepted. These not readily comparable, impacting on rates turn prevalence estimates, research, treatment. Methods The Vascular Impairment Cognition Classification Consensus Study (VICCCS) involved participants (81% academic researchers) from 27 countries an online Delphi consensus study....
Abstract Accurate lesion segmentation is critical in stroke rehabilitation research for the quantification of burden and accurate image processing. Current automated methods T1-weighted (T1w) MRIs, commonly used research, lack accuracy reliability. Manual remains gold standard, but it time-consuming, subjective, requires neuroanatomical expertise. We previously released an open-source dataset T1w MRIs manually-segmented masks (ATLAS v1.2, N = 304) to encourage development better algorithms....
Patients with post-coronavirus disease 2019 (COVID-19) conditions typically experience cognitive problems. Some studies have linked COVID-19 severity long-term damage, while others did not observe such associations. This discrepancy can be attributed to methodological and sample variations. We aimed clarify the relationship between outcomes determine whether initial symptomatology predict Cognitive evaluations were performed on 109 healthy controls 319 post-COVID individuals categorized into...
To investigate structural basal ganglia abnormalities in attention-deficit hyperactivity disorder (ADHD) and their relationship with the neuropsychological deficits behavioral problems found ADHD.Case-control study.Adolescents were recruited from a local polytechnic institute of secondary education.Eleven adolescents ADHD 19 healthy control subjects. Subjects diagnosed by school psychologist total population 450 students according to Diagnostic Statistical Manual Mental Disorders, Third...
One of the most prevalent symptoms post-COVID condition is cognitive impairment, which results in a significant degree disability and low quality life. In studies with large sample sizes, attention, memory, executive function were reported as long-term symptoms. This study aims to describe dysfunction individuals, compare objective neuropsychological performance those individuals without complaints, identify short exams that can differentiate from controls. To address these aims, Nautilus...
Functional outcomes after stroke are strongly related to focal injury measures. However, the role of global brain health is less clear. In this study, we examined impact age, a measure neurobiological aging derived from whole-brain structural neuroimaging, on poststroke outcomes, with focus sensorimotor performance. We hypothesized that more lesion damage would result in older which turn be associated poorer outcomes. Related, expected age mediate relationship between and Finally,...
Abstract Resting‐state studies conducted with stroke patients are scarce. The study of brain activity and connectivity at rest provides a unique opportunity for the investigation rewiring after plasticity changes. This sought to identify dynamic changes in functional organization default mode network (DMN) three months stroke. Eleven (eight male female; age range: 48–72) right cortical subcortical ischemic infarctions 17 controls (eleven males six females; 57–69) were assessed by...
After stroke, white matter integrity can be affected both locally and distally to the primary lesion location. It has been shown that tract disruption in mirror's regions of contralateral hemisphere is associated with degree functional impairment. Fourteen patients suffering right hemispheric focal stroke (S) eighteen healthy controls (HC) underwent Diffusion Weighted Imaging (DWI) neuropsychological assessment. The patient group was divided into poor (SP; n = 8) good (SG; 6) cognitive...
Objective Cushing's syndrome (CS) is associated with neuropsychological deficits. As the cerebellum plays a key role in functions it may be affected CS. The aim of this study was to investigate whether patients CS have smaller cerebellar volume than healthy controls, and analyse performance clinical parameters. Design A cross-sectional performed. Methods Thirty-six (15 active 21 remission) 36 controls matched for age, sex, education underwent testing, quality life assessment, evaluation,...
Resting-state studies conducted with stroke patients are scarce. First objective was to explore whether good cognitive recovery showed differences in resting-state functional patterns of brain activity when compared poor recovery. Second determine such were correlated performance. Third assess the existence prognostic factors for Eighteen right-handed and eighteen healthy controls included study. Stroke divided into two groups according their improvement observed at three months after...
<h3>BACKGROUND AND PURPOSE:</h3> There is a paucity of data on long-term neuroimaging findings from individuals who have developed the post-coronavirus 2019 (COVID-19) condition. Only 2 studies investigated correlations between cognitive assessment results and structural MR imaging in this population. This study aimed to elucidate outcomes participants with post-COVID-19 condition correlate these <h3>MATERIALS METHODS:</h3> A cohort 53 underwent 3T brain T1 FLAIR sequences obtained median...
Background The COVID-19 pandemic’s long-term mental health implications are increasingly concerning, especially among patients suffering post-acute sequelae of SARS-CoV-2 infection: Long COVID (LC) patients. Aim This study explores the presence and distribution anxiety, depression, stress in LC individuals with cognitive complaints northern Barcelona (Spain). Design & settings cross-sectional involved 155 diagnosed from “Aliança ProHEpiC-19 Cognitiu (APC)” project. Method Demographic...
The purpose of this prospective, between-subjects study was to look at impaired awareness cross-culturally in patients with traumatic brain injury (TBI) and relate after the initial estimates disturbed consciousness time injury. conducted community inpatient outpatient rehabilitation centers Barcelona Madrid. Participants were 30 persons primarily moderate severe TBI who could complete a written questionnaire concerning their functioning 28 age- gender-matched controls. A Spanish translation...
The primary goal of this study was to determine the incidence post-traumatic ventriculomegaly (Evans' index ≥ 0.30) in 95 head-injured patients with a Glasgow Coma Scale (GCS) score ≤13 at admission. Additional objectives were relationship between an increase ventricular size and several clinical radiological features outcome. A planimetric carried out sequential control computed tomography (CT) scans 34 moderately (GCS 9–13) 61 severely 3–8) minimum follow-up 2 months. Between two six CT...
Object. Data from many studies have demonstrated that shunt insertion in patients with idiopathic normal-pressure hydrocephalus (NPH) is associated high morbidity and a lack of significant improvement; however, the use strict diagnostic treatment protocols can improve results surgery these patients. The primary aim this prospective study was to analyze placement 43 NPH. A secondary determine relationship between several clinical neuroimaging factors, patient outcome after surgery. Methods....
<b>Background:</b> Normal pressure hydrocephalus (NPH) is associated with corpus callosum abnormalities. <b>Objectives:</b> To study the clinical and neuropsychological effect of callosal thinning in 18 patients idiopathic NPH to investigate postsurgical changes 14 patients. <b>Methods:</b> Global size seven subdivisions were measured. Neuropsychological assessment included an extensive battery assessing memory, psychomotor speed, visuospatial frontal lobe functioning. <b>Results:</b> After...
The association of cerebral white matter lesions (WMLs) with cognitive status is not well understood in middle-aged individuals. Our aim was to determine the specific contribution periventricular hyperintensities (PVHs) and deep (DWMHs) function a community sample asymptomatic participants aged 50 65 years. One hundred stroke- dementia-free adults completed comprehensive neuropsychological battery brain MRI protocol. Participants were classified according PVH DWMH scores (Fazekas scale). We...
<b><i>Background:</i></b> Risk factors for vascular cognitive impairment (VCI) are the same as traditional risk cerebrovascular disease (CVD). Early identification of subjects at higher VCI is important development effective preventive strategies. In addition to (VRF), circulating biomarkers have emerged potential tools early diagnoses, they could provide in vivo measures underlying pathophysiology. While VRF been consistently linked a profile (i.e., deficits...
<h3>OBJECTIVES</h3> To establish whether surgery can improve the neuropsychological functioning of young adult patients with spina bifida and apparent clinically arrested hydrocephalus showing abnormal intracranial pressure. <h3>METHODS</h3> Twenty three adults assumed (diagnosed as active or compensated by continuous pressure monitoring) underwent surgery. All received examination before 6 months later. Neuropsychological assessment included tests verbal visual memory, visuospatial...
Cushing's syndrome (CS) is associated with high cardiovascular risk. White matter lesions (WML) are common on brain magnetic resonance imaging (MRI) in patients increased risk.To investigate the relationship between risk, WML, neuropsychological performance and volume CS.Thirty-eight CS (23 remission, 15 active) 38 controls sex-, age- education-level matched underwent a clinical evaluation, blood urine tests 3Tesla MRI. WML were analysed Scheltens scale. Ten-year risk (10CVR) vascular age...