- Neurobiology of Language and Bilingualism
- Spatial Neglect and Hemispheric Dysfunction
- Dementia and Cognitive Impairment Research
- Action Observation and Synchronization
- Face Recognition and Perception
- Hemispheric Asymmetry in Neuroscience
- Neural and Behavioral Psychology Studies
- Alzheimer's disease research and treatments
- Language, Metaphor, and Cognition
- Stroke Rehabilitation and Recovery
- Reading and Literacy Development
- Medical and Biological Sciences
- Psychosomatic Disorders and Their Treatments
- Memory and Neural Mechanisms
- Language Development and Disorders
- Multisensory perception and integration
- Neurological Disorders and Treatments
- Categorization, perception, and language
- Facial Nerve Paralysis Treatment and Research
- Functional Brain Connectivity Studies
- Musculoskeletal pain and rehabilitation
- Neurology and Historical Studies
- EEG and Brain-Computer Interfaces
- Motor Control and Adaptation
- Cholinesterase and Neurodegenerative Diseases
Università Cattolica del Sacro Cuore
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2025
Fondazione Santa Lucia
2013-2023
Uninett (Norway)
2023
Agostino Gemelli University Polyclinic
2012-2021
University of Bristol
2017
Catholic University of America
1976-2016
University of Gothenburg
2016
University of Cambridge
1981-2016
University of Toronto
2016
This study aimed at investigating the clinical usefulness of Mental Deterioration Battery (MDB) in neuropsychological diagnosis and characterization dementia syndrome. In this paper, we report: (a) normative data for various test scores derived from analysis performance 340 normal subjects living urban areas; (b) an evaluation reliability single tests battery as a whole differentiating patients affected by cognitive deterioration 130 rural areas 134 probable Alzheimer’s dementia; (c) cluster...
In 2008 a task force was set up to develop revision of the European Federation Neurological Societies (EFNS) guideline for diagnosis and management Alzheimer's disease (AD) other disorders associated with dementia, published in early 2007. The aim this revised international present peer-reviewed evidence-based statement guidance practice clinical neurologists, geriatricians, psychiatrists, specialist physicians responsible care patients AD. Mild cognitive impairment non-Alzheimer dementias...
Two unselected groups of patients, affected by a mono-hemispheric cerebral lesion, were studied in two seperate services means various tasks copying drawings, order to check the hypothesis qualitative difference between unilateral spatial neglect (USN) right and left brain-damaged patients. In both experimental drawing asymmetries found be slight importance among hemispheric consisting chiefly tendency omit some figures lying on half models, definitely more severe braindamaged where main...
Abstract Introduction Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack consensus on diagnosis, reflecting the use multiple different assessment protocols. A large multinational group clinicians researchers participated a two‐phase Vascular Impairment Cognition Classification Consensus Study (VICCCS) to agree principles (VICCCS‐1) protocols (VICCCS‐2) for diagnosis VCI. We present VICCCS‐2. Methods used VICCCS‐1 published diagnostic...
Background and objectives The last version of the EFNS dementia guidelines is from 2007. In 2010, revised for Alzheimer's disease ( AD ) were published. current involve revision syndromes outside , notably vascular cognitive impairment, frontotemporal lobar degeneration, with Lewy bodies, corticobasal syndrome, progressive supranuclear palsy, Parkinson's dementia, Huntington's disease, prion diseases, normal‐pressure hydrocephalus, limbic encephalitis other toxic metabolic disorders. aim to...
Abstract Introduction Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none been universally accepted. These not readily comparable, impacting on rates turn prevalence estimates, research, treatment. Methods The Vascular Impairment Cognition Classification Consensus Study (VICCCS) involved participants (81% academic researchers) from 27 countries an online Delphi consensus study....
Abstract A category-specific semantic disorder, selectively affecting Living things and food sparing inanimate objects, was observed in a patient (LA) who had made partial recovery from herpes simplex encephalitis. This impairment to have similar characteristics both with verbal pictorial material, significant degree of consistency between repeated presentations across various modalities administration the same stimuli. In order study possible role interactions verbal-semantic...
Posner has suggested that unilateral spatial neglect could be due to a difficulty in disengaging attention from its current focus orient it toward the neglected half space. Clinical and experimental data suggest, however, this only one aspect of more complex disturbance also characterized by an early automatic orienting space ipsilateral lesion. To test hypothesis, two different investigations unselected groups patients with right left brain-damage were carried out. The first investigation,...
The aim was to evaluate the effects of poststroke depression and antidepressant therapy on improvement motor scores disability, verify if negative functional recovery could be counterbalanced by taking drugs. RESULTS OBTAINED BEFORE, DURING, AND AFTER REHABILITATION: On Barthel index, Canadian neurological scale, Rivermead mobility index-by 49 depressed patients with stroke, who had been treated (n=25) or not (n=24) according different therapeutic approaches their physicians, were compared...
Eighty-three control subjects and 200 patients suspected of diffuse cerebral damage were submitted to the Mental Deterioration Battery. Three independent judges evaluated each patient on basis all available data. Only 103 patients, unanimously classed as demented by three retained. On controls' performances, scores obtained in various tests corrected for age educational level. Both single Battery a whole discriminated normal controls from at very satisfactory
We report the case of a patient (C.O.) who showed selective defect in recognition familiar people, with very mild disease progression during period 30 months resulting from focal atrophy right temporal lobe. On formal neuropsychological testing, C.O. obtained high scores on tests general intelligence, episodic memory, language, executive functions, attention, visual and visual–spatial abilities. more specific tasks unfamiliar face recognition, scored above controls' means perceptual tests,...
Abstract Two main dichotomies have been put forth in the study of anatomical substrates emotional behaviour. The first, more classical and firmly established, claims that basic brain mechanisms for emotions are located subcortical rather than cortical structures. second, recent still hypothetical dichotomy, maintains right left hemispheres not equally involved behaviour hemisphere plays a critical role this regard. It is clear, however, if these two independent or somehow interconnected. aim...
Using a quantitative measure, we analyzed the relationship between visuospatial and representational neglect in right- left-brain-damaged patients found signs of only right-brain-damaged patients. Although was always associated with neglect, suggesting that two forms share common underlying mechanism, most frequent finding isolation. A strong influence phenomenon attentional attraction toward space ipsilateral to lesion visuospatial, as opposed imaginal, tasks can account for this finding.
<b>Background:</b> In vivo evaluation of cholinergic circuits the human brain has recently been introduced using a transcranial magnetic stimulation (TMS) protocol based on coupling peripheral nerve with motor cortex TMS (short latency afferent inhibition, SAI). SAI is reduced in Alzheimer’s disease (AD) and drugs enhancing transmission increase SAI. <b>Methods:</b> We evaluated whether testing, together test-retest, after single dose acetylcholinesterase (AChE) inhibitor rivastigmine, might...
Patients who survive herpes simplex encephalitis (HSE) sometimes present a category-specific disorder for living things. Since HSE specifically involves the temporolimbic structures of both hemispheres, these could play critical role in processing and storing information about If this were case, same items should also be observed early stages dementia Alzheimer type (DAT) as are often severely affected condition. To test hypothesis, we administered to 15 DAT patients 10 normal controls...
Abstract A neuropsychological test battery made up of verbal, visual-spatial, and intelligence tests was administered to 82 right 67 non-aphasic left brain-damaged patients with localized cerebral lesions, in order draw impairment profiles the various subgroups. Separate analyses were undertaken on unilobar multilobar lesions. As for hemisphere effects, LH performed worse than RH subjects verbal tests, while reverse true visual-spatial tasks. lobe frontal damage fared other subgroups word...