A5029222572- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Renal and Vascular Pathologies
- Central Venous Catheters and Hemodialysis
- Vascular Procedures and Complications
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Complement system in diseases
- Renal Diseases and Glomerulopathies
- Organ Donation and Transplantation
- Pharmacological Effects and Toxicity Studies
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Parasitic infections in humans and animals
- Inflammatory Biomarkers in Disease Prognosis
- Venous Thromboembolism Diagnosis and Management
- Blood groups and transfusion
- Liver Disease and Transplantation
- Vascular Malformations Diagnosis and Treatment
- Parasites and Host Interactions
- Diagnosis and Treatment of Venous Diseases
- Genetic and Kidney Cyst Diseases
- Adolescent and Pediatric Healthcare
- Metabolism and Genetic Disorders
- Pregnancy and Medication Impact
Korea University Medical Center
2021-2025
Korea University
2022-2024
Seoul National University
2019-2022
New Generation University College
2022
Seoul National University Hospital
2019-2021
The 2019 Kidney Disease Outcome Quality Initiative guidelines emphasize the importance of selecting dialysis based on life expectancy patient. However, it is difficult to predict a patient during arteriovenous fistula creation. We investigated whether neutrophil-to-lymphocyte, monocyte-to-lymphocyte, and platelet-to-lymphocyte ratios measured before could mortality. Between January 2016 December 2020, we retrospectively analyzed electronic medical records 448 patients aged ≥ 70 years...
Abstract This study analyzed the association between medication adherence and intrapatient variability (IPV) of tacrolimus concentrations among kidney transplant recipients through a post hoc analysis dataset from recently conducted randomized controlled trial. Among 138 patients enrolled in original trial, 92 with ≥ 5 months event monitoring system (MEMS) use 4 trough values were included this analysis. The levels was calculated using coefficient variation (CV) mean absolute deviation....
Tacrolimus intra-patient variability (IPV) is a novel predictive marker for long-term kidney transplantation outcomes. We examined the association between IPV and calcineurin inhibitor (CNI) nephrotoxicity impact of pharmacogenes on CNI IPV. Among transplant recipients at our hospital January 2013 December 2015, records 80 patients who underwent 1-year protocol renal allograft biopsy agreed to donate blood samples genetic analysis were retrospectively reviewed. The cohort was divided into...
Abstract Background The intrapatient variability (IPV) of tacrolimus (Tac) is associated with the long‐term outcome kidney transplantation. CYP3A single‐nucleotide polymorphism (SNP) may affect IPV Tac. We investigated impact and genetic in pediatric patients who received Methods A total 202 renal transplant recipients from 2000 to 2016 were analyzed retrospectively. was calculated between 6 12 months after surgery. Among these patients, CYP3A5 67 patients. Results group high had a...
Studies in western countries have shown a decline the incidence of ruptured abdominal aortic aneurysm (rAAA) with advancements endovascular repair and screening. However, according to health insurance data Korea based on rAAA code (I71.3), overall has been increasing. This study aimed validate I71.3 for attempt define true Korea.A 20-year multicenter retrospective review was undertaken from period January 1, 2000 December 31, 2020. All patients were diagnosed each 4 hospitals. The CT images...
Native arteriovenous fistula (AVF) is the first choice for hemodialysis access; however, maturation failure rate remains high. Hence, balloon-assisted (BAM) increasingly being used to overcome failure. This study evaluated outcomes of BAM and compared differences between radial-cephalic (RC) brachial-cephalic (BC) AVF.Between January 2013 December 2017, 1,622 new AVFs were created. was considered if AVF did not satisfy criteria hemodynamic (6-mm diameter 500-mL/min flow within 8 weeks after...
Tacrolimus (TAC) is an immunosuppressant widely prescribed following allogenic organ transplant. Due to wide interindividual pharmacokinetic (PK) variability, optimizing TAC dosing based on genetic factors required minimize nephrotoxicity and acute rejections.We enrolled 1133 participants receiving from 4 cohorts, consisting of 3 with kidney transplant recipients 1 healthy males clinical trials. The effects were estimated appropriately control confounding variables. A genome-wide association...
Extrahepatic portal vein obstruction (EHPVO) is the most common cause of pediatric hypertension and can life-threatening variceal bleeding. Meso- Rex shunt (MRS) a surgical procedure that restores physiological venous blood flow to liver by using graft connect superior mesenteric left within recess, relieve bleeding other complications associated with EHPVO. Although MRS regarded as an optimal potentially curative treatment good long-term patency, thrombosis or failure due unknown causes not...
A 58-year-old male patient with severe claudication due to thrombosis of the left ilio-femoro-popliteal artery aneurysm. He also had a venous stasis ulcer history multiple embolotherapy arteriovenous malformation. Duplex sonography revealed reflux and varicose veins great saphenous vein (GSV). sequential bypass surgery was performed that consisted excision external iliac common femoral aneurysm, deep interposition an expanded polytetrafluoroethylene graft, femoro-posterior tibial reversed...
Abstract With small kidneys, EBKTs could provide sufficient renal mass but lead to inefficient use of resources, while SKTs result in insufficient function due mass. We aimed compare the outcomes EBKT and SKT from donors weighing ≤15 kg pediatric recipients. retrospectively reviewed all patients who met inclusion criteria between January 1, 1984, April 30, 2019, at a single institution. Of total 23 patients, 12 received 11 SKT. The median age donors, weight recipients were comparable two...
Intravascular fasciitis (IVF) is a very rare disease that difficult to diagnose preoperatively. Frequently, it can be misdiagnosed as malignancy or deep vein thrombosis. A 26-year-old man presented with 6-month history of intermittent cramping pain in the right calf. Duplex ultrasonography, computed tomography, magnetic resonance imaging, and positron emission tomography were performed various hospitals. The work-up revealed hypermetabolic mass femoral vein, suggestive malignancy, such...
Objective Endovascular aortic aneurysm repair (EVAR) is the primary treatment for abdominal aneurysms, constituting 70%–80% of interventions. Despite initial benefits, long-term studies show increased mortality. Using nationwide data, this study assesses outcomes EVAR, open (OAR), and EVAR explantation (EE) in Korea, while exploring characteristics late conversion, including rising EE incidence. Methods Employing National Health Insurance Service database, covering health-related data nearly...
Introduction: Optimizing vascular access for hemodialysis in end-stage kidney disease is crucial. While arteriovenous fistulas (AVFs) are preferred better patency and fewer complications, many patients require alternatives options like grafts (AVGs) due to anatomical constraints. This study compares outcomes between elbow upper arm (UA) basilic veins forearm loop AVGs, highlighting the potential benefits of UA vein improve feasibility with poor through retrospective analysis. Methods:...
Recent guidelines recommend restrictive red blood cell transfusion; therefore, hospitals have started introducing and implementing patient management programs. This is the first study to analyze changes in trends of transfusions whole population over past 10 years according sex, age group, component, disease, hospital type.This cohort analyzed transfusion records for years, from January 2009 December 2018, using nationwide population-based data Korean National Health Insurance Service-Health...
Purpose: The number of older patients who need vascular access for end-stage renal disease is rapidly increasing. However, determining the optimal difficult. We aimed to compare outcomes radiocephalic (RC) and brachiocephalic (BC) arteriovenous fistula (AVF) in aged >80 years. Methods: This study included 94 undergoing hemodialysis underwent procedure first time between 2013 2019 Korea University Guro Hospital. primary were patency (PP) cumulative (CP). secondary outcome was maturation...
Background: Genetic mutation of specific genes is the common cause end-stage renal disease (ESRD) in children, and nephronophthisis (NPHP) most genetic ESRD children. Kidney transplantation selected as treatment choice for pediatric patients with nephronophthisis. Nevertheless, long-term outcome kidney NPHP remains uncertain there are few data on survival transplants This study aims to analyze patients. Materials Methods: A retrospective chart review was performed including undergoing at our...
Introduction: Pre-transplant anti-human leukocyte antigen (HLA) donor specific antibodies (DSA) have been known to be associated with outcomes after kidney transplantation. In particular, several studies demonstrated that DSA affects early antibody-mediated rejection (ABMR). The aim of this study was investigate factors affecting pathologic outcome in recipients pre-transplant DSA. Materials and Methods: Between January 2008 September 2019, data were collected retrospectively at a single...
The effects of renal transplantation in patients with augmentation cystoplasty are still controversial. We retrospectively analyzed nine who underwent after cystoplasty.A total prior to between January 1990 and May 2020 were reviewed. Basic information on cystoplasty, transplant procedures, long-term outcomes analyzed.The bowel segments utilized for the stomach two (one patient needed revision using ileum), ileum four patients, ileocolic pouch one patient, sigmoid ureter patient. All...
C1q nephropathy is an uncommon type of glomerulonephritis characterized by extensive and dominant mesangial deposition in the absence systemic lupus erythematosus. However, there are limited studies about renal allografts. This study aimed to report prevalence transplanted kidney allograft biopsies describe its clinical histopathologic features.Between January 2005 December 2018, a total 1,742 transplantations were performed at Seoul National University Hospital. All (n=10,217) these...
The platelet function analyzer (PFA)-100/200 is widely used to assess function. However, its role in predicting the perioperative risk of bleeding patients undergoing liver resection remains controversial. Therefore, we aimed ascertain whether test could be useful hepatic surgery.The study participants were who underwent hepatectomy for hepatocellular carcinoma at our hospital over a period 10 years from January 1, 2010 May 31, 2020. PFA-200 values these divided into 2 groups; normal (n =...
The National Kidney Foundation Disease Outcomes Quality Initiative (NKF-KDOQI) guidelines recommend forearm arteriovenous grafts (AVGs) as an alternative procedure to transposed basilic vein fistulas for providing secondary access during hemodialysis. Recently, autogenous elevated brachial-brachial (BVE) have become increasingly popular. aim of this study was compare the outcomes BVE and loop AVG (AVG) in hemodialysis.We retrospectively reviewed medical records patients who had received a or...
A 52-year-old female was transferred with a 2-year history of intermittent claudication and high blood pressure (BP).She treated for rheumatoid endocarditis in childhood.The BPs the left arm right were 187/99 169/90 mmHg, respectively.Carotid bruit absent pulses all four extremities palpable.Blood tests including inflammatory markers unremarkable.Computed tomography showed tight segmental narrowing abdominal aorta, severe stenosis bilateral renal Image Vascular Surgery