- Advanced Radiotherapy Techniques
- Glioma Diagnosis and Treatment
- Head and Neck Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Brain Metastases and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced MRI Techniques and Applications
- Salivary Gland Tumors Diagnosis and Treatment
- Ultrasound and Hyperthermia Applications
- Cancer Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiation Effects and Dosimetry
- Ocular Oncology and Treatments
- Nonmelanoma Skin Cancer Studies
- Advances in Oncology and Radiotherapy
- COVID-19 and healthcare impacts
- Radiation Dose and Imaging
- Colorectal Cancer Treatments and Studies
- Effects of Radiation Exposure
- Bladder and Urothelial Cancer Treatments
- Medical Imaging Techniques and Applications
- Histone Deacetylase Inhibitors Research
- Cancer, Stress, Anesthesia, and Immune Response
- Cancer and Skin Lesions
- Oral Health Pathology and Treatment
All India Institute of Medical Sciences
2011-2025
Cancer Institute (WIA)
2020-2025
Oklahoma State University
2024
Henry Ford Hospital
2024
Post Graduate Institute of Medical Education and Research
2021
All India Institute of Medical Sciences Bhopal
2021
All India Institute of Medical Sciences Raipur
2021
Erasmus MC
2019
Indira Gandhi Medical College
2018-2019
Erasmus MC Cancer Institute
2018
The World Health Organization (WHO) has declared coronavirus disease 2019 (COVID-19) as pandemic in March 2020. Currently there is no specific effective treatment for COVID-19. major cause of death COVID-19 severe pneumonia leading to respiratory failure. Radiation low doses (<100 cGy) been known its anti-inflammatory effect and therefore, dose radiation therapy (LDRT) lungs can potentially mitigate the severity reduce mortality. We conducted a pilot trial study feasibility clinical efficacy...
ABSTRACT Background Extranodal extension (ENE) is an important adverse prognostic indicator for head and neck cancers. However, ENE needs further risk stratification in terms of optimum cutoff the extent interaction with clinicopathological factors. Methods Retrospective single‐center study on patients treatment‐naïve cancer final histology indicating ENE. Results Pathological was observed 122 (12.4%). With 2 mm separating Mi‐ENE Ma‐ENE, no difference overall survival (OS) disease‐free (DFS)...
Stereotactic body radiotherapy (SBRT) for pulmonary oligometastatic disease achieves excellent treatment outcomes in terms of local control and toxicity. Patients treated with SBRT are often elderly have multiple co-morbidities. This subset patients may experience different survival as compared to young fit subjected radical metastasectomies. The purpose this retrospective study was evaluate OS identify factors associated inoperable oligometastases SBRT.Criteria used selection included:...
Oligometastases refers to a state of limited metastatic disease. The use local ablative therapies patients with oligometastases can result in durable remission or long-term cure. Stereotactic body radiotherapy (SBRT) is highly conformal radiation technique that delivers doses the target. study aimed evaluate control (LC) and identify factors associated poor LC pulmonary treated SBRT. Primary endpoint was assess LC; secondary determine LC.Criteria used for selection included: disease maximum...
Treatment compliance of elderly patients to intensive multi-modality cancer therapy can be challenging and has not been adequately addressed in developing countries. The present study evaluated head neck carcinomas cancer-directed therapy.Forty-seven HNSCC were the study. Patients assessed as per stage site disease, general condition, performance status, any pre-existing co-morbidities. Compliance was defined who able complete intended at primary clinic. Non-compliance stratified early, mid-...
ABSTRACT Background The World Health Organization (WHO) has declared coronavirus disease 2019 (COVID-19) as pandemic in March 2020. Currently there is no vaccine or specific effective treatment for COVID-19. major cause of death COVID-19 severe pneumonia leading to respiratory failure. Radiation low doses (<100 cGy) been known its anti-inflammatory effect and therefore, dose radiation therapy (LDRT) lungs can potentially mitigate the severity reduce mortality. We conducted a pilot trial...
A torted wandering spleen is a rare clinical occurrence with fewer than 500 cases reported and an incidence of less 0.2%. It brought about through laxity the gastrosplenic splenorenal ligaments; however, precise aetiology remains unknown. can prove to be diagnostic challenge high mortality if misdiagnosed. We present case 27-year-old woman Arabic ethnicity, who complained short history severe abdominal pain background recurrent vomiting. An computerized tomography scan revealed spleen. This...
To investigate prognostic factors for death within 6 months of stereotactic body radiotherapy (SBRT) patients with peripheral early-stage non-small cell lung cancer (NSCLC).This analysis included 586 NSCLC tumors treated SBRT. Potential patient and tumor factors, including the Charlson Comorbidity Index (CCI) Cumulative Illness Rating Scale (CIRS), were analyzed by logistic regression association early mortality (death <6 after SBRT). Additionally, CCI CIRS compared respect to their...
Granulocytic sarcoma (GS) is a rare extramedullary malignant tumor composed of immature myeloid cells. It strongly associated with acute leukaemia, chronic myeloproliferative diseases. Occurrence GS in the oral cavity extremely uncommon. Present case reported an unusual occurrence without leukemia involving maxillary sinus child. The patient underwent chemotherapy followed by radiotherapy complete remission. A long-term follow-up was carried any evidence recurrence special focus on...
Sebaceous carcinoma is a rare malignancy of the skin appendages. It tends to occur in elderly patients. Orbital region most commonly involved site seen 75% cases. The involvement extra-orbital sites infrequent. Herein, case extra-ocular sebaceous arising scalp 20-year-old man described.The patient developed tumor relapse after excision biopsy. He was treated with wide local tumor. However, recurrence an interval four months for which he again underwent excision. did not manifest any regional...
Purpose: Evaluation of the newly integrated system for its validation and designing a quality assurance frame work to assess geometrical, radiological mechanical accuracy. Methods : Isocentric accuracy two independent imaging modalities, kV based ExacTrac MV iViewGT was evaluated using Winston-Lutz test. A pelvic humanoid phantom used end-to-end test clinical utilization. Image systems Las Vegas Phantom ETR-1 plate. The also assessed kVp accuracy, - dose linearity, mAs-dose linearity timer...
Purpose: To describe the design and characteristics of a novel linac‐based MRI guided radiation therapy system that addresses RF magnetic field interference can be housed in conventional radiotherapy vaults. Methods: The MR‐IGRT will provide simultaneous MR imaging combined with both simple (3D) complex (IMRT, SBRT, SRS) techniques. is combination a) double‐donut split solenoidal superconducting 0.345T MRI; b) 90 cm isocenter ring‐gantry mounted 6MV, flattening filter‐free linac coupled...
Abstract Caregivers serve a critical role in assisting their loved ones, though providing care can be associated with physical and cognitive decline. We investigated disparities memory lapses perceived impact on daily functioning among caregivers non-caregivers. focused prospective (PM; i.e., for future actions) retrospective (RM; remembering information from the past). Participants included respondents of Midlife United States Refresher 1: Daily Diary Project dataset (Ryff & Almeida,...
TPS12150 Background: Head and neck squamous cell carcinoma (HNSCC) is common in the Indian subcontinent majority (65%) patients present an advanced stage. Chemotherapy related cognitive impairment (CRCI) a poorly defined underestimated phenomenon HNSCC population. Through this study, we are attempting to establish evidence of activity agents targeting neuro-inflammation reducing or halting decline associated with definitive chemoradiotherapy for head malignancies without adding...
TPS149 Background: The SWOAR is a phase III trial (ClinicalTrials.gov ID NCT05187091) evaluating sparing of dysphagia/aspiration related structures (DARS) & submandibular gland by IMRT. Methods: Patients with T1-4, N0-3, M0 oropharynx, larynx and hypopharynx treated radical RT were randomized to arm A (standard IMRT) or B (DARS in 1:1 manner. Treatment allocation was done based on T stage, concurrent chemotherapy use (weekly 40mg/m 2 ) subsite. A10-point improvement MD Anderson Dysphagia...
Abstract Brainstem Gliomas have limited therapeutic options and poor outcomes. Radiation forms the cornerstone of management but data is lacking. We performed an audit brainstem glioma patients treated with hypofractionated radiation between July 2021 to May 2024. Diagnostic MRI was co-registered planning CT delineate GTV isotropic 5 mm margin for CTV 3mm PTV. Baseline clinical imaging details, acute toxicities, steroid usage, progression, overall survival were recorded. PFS OS defined from...