A5012445964- Nail Diseases and Treatments
- Antifungal resistance and susceptibility
- Phytochemistry Medicinal Plant Applications
- Plant Pathogens and Fungal Diseases
- Fungal Infections and Studies
- Essential Oils and Antimicrobial Activity
- Microbial Natural Products and Biosynthesis
- Bioactive Compounds and Antitumor Agents
- Pharmaceutical and Antibiotic Environmental Impacts
- Pineapple and bromelain studies
- Microbial Metabolism and Applications
- Morinda citrifolia extract uses
- Science and Education Research
- Agricultural and Food Sciences
- Phytochemistry and Bioactivity Studies
- Microbial Metabolites in Food Biotechnology
- Enzyme Catalysis and Immobilization
- Antibiotic Resistance in Bacteria
- Environmental Chemistry and Analysis
- Metabolomics and Mass Spectrometry Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Food Chemistry and Fat Analysis
- Metabolism, Diabetes, and Cancer
- Plant Toxicity and Pharmacological Properties
- Fern and Epiphyte Biology
National Institute of Amazonian Research
2006-2025
Universidade Federal do Amazonas
2023-2024
Brazilian Agricultural Research Corporation
2024
Universidade do Estado do Amazonas
2023
Amazon (Germany)
2023
Fundação de Medicina Tropical
2023
Amazon (United States)
2023
Escola Superior de Ciências da Saúde
2023
Children's Hospital
1998
Abstract Pathogenic strains of Escherichia coli can cause gastrointestinal infections, urinary tract infections (UTIs), bacteremia, and other severe infections. Some isolates this species are capable producing extended-spectrum β-lactamase (ESBL) enzymes, which mediate resistance against penicillin derivates cephalosporins. Fungi the Ascomycota phylum known to produce antibiotics from different classes with activity various bacterial agents. Among them, genera Penicillium, Cephalosporium,...
Carotenoids are natural pigments responsible for the yellow, orange, and red colors seen in various organisms. The aim of this study was to investigate potential yeast strains belonging genus Rhodotorula isolated from Amazon Region production carotenoids. Environmental samples were collected isolation. Isolates showing pigmented colonies underwent morphological biochemical studies, as well assessment their carotenoid production. three best producers identified through nucleotide sequencing...
Abstract This study investigates the impact of moisture and wheat bran supplementation on biological efficiency (BE) nutritional profile Pleurotus ostreatus (Jacq.) P. Kumm cultivated peels Astrocaryum aculeatum G. Mey. Utilizing a factorial design, variations in substrate composition were systematically analyzed to determine optimal conditions for mushroom yield. The methodology encompassed strain acquisition, spawn preparation, fruiting induction, calculation, chemical analysis both...
Heteroresistance, defined as the occurrence of apparently homogeneous subpopulations microbial cells showing different levels antimicrobial susceptibility is a problem that has been associated with therapeutical failure in cryptococcosis. The purpose study was an investigation on level heteroresistance to fluconazole (LHF) observed clinical and environmental C. neoformans/C. gattii complex species isolates from Amazonas State (AM), Brazil. A total 45 9 type strains were analyzed. assessments...
FUNDAMENTOS: Micoses superficiais estritas são infecções fúngicas que se localizam nas camadas da pele e seus anexos. As micoses cutâneas representadas pelas dermatofitoses candidíases podem ultrapassar a camada córnea pele. Na região amazônica possuem incidência elevada. OBJETIVOS: Estudar as superficiais, cutâneas, diagnosticadas sob o ponto de vista epidemiológico micológico. PACIENTES E MÉTODOS: Pacientes com suspeita clínica submetidos exame micológico no período março novembro 2003...
In the Amazon, use of medicinal plants by native populations is an important source ethnopharmacological knowledge. Vismia guianensis (Aubl.) Choisy widely used against diseases caused fungi. Thus, aim this work was to evaluate antifungal potential species and influence extractive parameters on activity. Dried extracts were prepared from leaves tested for activity fungal Candida albicans, Malassezia furfur, Trichophyton rubrum. The most promising extract obtained with polar solvents...
Aquatic ecosystems in tropical forests have a high diversity of microorganisms, including fungi, which are important decomposers submerged wood. Despite the importance their role decomposition, research concerning freshwater fungi from Brazilian Amazonian environments is scarce. The aim this work was to describe composition and present on wood two lakes Amazon (State Pará). Fragments decaying (30 samples per lake) were collected Lakes Juá Maicá. inspected for 6 months presence fungal...
Substances that inhibit the growth of Mycobacterium tuberculosis could potentially be used as antibiotics.These substances also added to test culture media improve speed diagnosis.The aim this work was investigate influence filtrates endophytic fungi isolated from P. aduncum L. on M. tuberculosis.To achieve objective, following methodology used: a) were leaves and stems L.; b) submitted submerged bioprocessing; c) bioprocess assayed evaluate their effect tuberculosis.We 315 fungal types,...
The emergence of multidrug resistance in bacterial pathogens is a growing public health concern requiring solutions including the discovery new antimicrobial drugs. Fungi have been used for decades as source antimicrobials. Ongoing screenings newly characterized fungal strains producing antimicrobials include environments that are difficult to access like deep sea, glaciers, wastewaters and polluted due human activity. In present study, microorganisms were isolated from water samples taken...
Endopleura uchi is a plant native to the Amazon and its chemical pharmacological potential has been widely studied. Bertholletia excelsa oilseeds (Brazil nut) are global highlight, with diverse applications in cosmetic pharmaceutical industries. Therefore, this work provided premises assist development of cream formulations dried extract from stem bark oil ability inhibit strains Candida spp. For this, was prepared for 5 minutes decoction using 10% (w/v). Drying carried out fluidized bed...
<abstract> <p>The tropical fruit cupuassu comes from <italic>Theobroma grandiflorum</italic> (SCHUM), a close relative of cocoa. Cupuassu has rich yet delicate flavour profile with notes chocolate, pineapple, passion and other fruits. Here, we produced cupuassu-fruit wine using <italic>Saccharomyces cerevisiae</italic> inoculum (and univariate analysis to determine conditions for optimum ethanol production) then fermented this produce unique vinegar...
Abstract Background The rising prevalence of fungal infections and challenges such as adverse effects resistance against existing antifungal agents have driven the exploration new substances. Methods We specifically investigated naphthoquinones, known for their broad biological activities promising capabilities. It examined a particular naphthoquinone on cellular components Candida albicans ATCC 60193. study also assessed cytotoxicity in MRC-5 cells, Artemia salina , seeds tomatoes arugula....
<p>This work focuses on optimizing laccase production from <italic>Pleurotus ostreatus</italic> (Jacq.) P. Kumm. using tucumã (<italic>Astrocaryum aculeatum</italic> G. Mey.) and pupunha (<italic>Bactris gasipaes</italic> Kunth) fruit peels as substrates assessing the influence of environmental parameters such moisture content % (w/w) wheat bran supplementation (w/w). Both demonstrated potential for substantial activity, with reaching optimal levels...
The emergence of bacterial resistance to antimicrobials poses a significant health threat. To address this issue, exploring the fungal diversity in freshwater environments Amazon Forest has potential search for new antimicrobials. This study aimed investigate production antibacterial metabolites by aquatic fungi from lakes, specifically Lake Juá and Maicá (Brazil-PA). isolates were obtained wood fragments submerged these ethyl acetate extracts evaluated activity against Staphylococcus aureus...
This study aimed at improving a real-time polymerase-chain-reaction (qPCR) assay for the detection of Histoplasma capsulatum, fungal pathogen that can cause severe respiratory infections in humans, clinical and soil samples.Primer probes were in-silico designed, in-vitro evaluated including biopsy materials finally subjected to real-world application with collected samples.Applying qPCR liver lung biopsies from 71 patients each, 59 infected human immunodeficiency virus (HIV), as well...
The increase in fungal infections, accompanied by adverse effects and acquired resistance associated with the use of antifungal agents used for their clinical management, have facilitated search new substances properties. Naphthoquinones been investigated due to multiple biological activities, including significant potential. This study aimed at evaluating potential naphthoquinones against opportunistic fungi dermatophytes assess impact a selected naphthoquinone on formation cell wall,...
Protium Burm. f. (Burseraceae) is well known in the Brazilian Amazon for its diversity of species, though some them are difficult to identify based on only morphological characteristics. We investigated species puncticulatum J.F. Macbr. and tenuifolium (Engl.) Engl. relation their chemical constituents biological aspects. The phytochemical study hexane extract from trunk P. led identification a mixture triterpenes: α, β-amyrin (1 2), lupeol (3); methanolic gave lignans 7-oxo-parabenzolactone...
Abstract The stingless bees Melipona interrupta and seminigra have great ecological importance as pollinators economical for its honey production. They are associated with a diversity of entomofauna microbiota. To understand more about the microbiota these species, this study carried out morphological molecular identification fungi present in internal hive environment brood cells larvae pupae (queen workers) M . , during rainy dry seasons. Isolated were identified by two methods: analysis...