- Congenital Heart Disease Studies
- Mechanical Circulatory Support Devices
- Transplantation: Methods and Outcomes
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Organ Transplantation Techniques and Outcomes
- Congenital Diaphragmatic Hernia Studies
- Cardiac Valve Diseases and Treatments
- Tracheal and airway disorders
- Cardiovascular Conditions and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac, Anesthesia and Surgical Outcomes
- Diversity and Career in Medicine
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrhythmias and Treatments
- Vascular anomalies and interventions
- Renal Transplantation Outcomes and Treatments
- PARP inhibition in cancer therapy
- Acute Kidney Injury Research
- Surgical Simulation and Training
- Acute Myocardial Infarction Research
- Healthcare Policy and Management
- Intestinal and Peritoneal Adhesions
- Wireless Power Transfer Systems
- Abdominal Surgery and Complications
Norton Hospital
2019-2024
Kosair Children's Hospital
2019-2024
University of Louisville
2016-2024
American Association for Thoracic Surgery
2024
Emory University
2024
Children's Healthcare of Atlanta
2024
University of Colorado Denver
2009-2023
Children's Hospital Colorado
2009-2023
Chestnut Hill College
2023
Norton Healthcare
2020
Abstract OBJECTIVES Heart transplantation for adult congenital heart disease is complicated and associated with challenging pretransplant support, long waiting high early post-transplant mortality. We explored if surgical medical advances allocation system changes have affected outcomes. METHODS From United Network Organ Sharing database, adults listed were queried. To explore practice outcome trends, patients divided into 4 eras (eras 1–3: nearly 3 equal periods from 1992 to 2018, era 4:...
Erythropoietin is known to stimulate red cell production and has recently been shown protect the heart against injury from ischemia/reperfusion. However, it unknown whether darbepoetin alfa (Dpa), a long-acting analog of erythropoietin, can play protective role myocardial infarction. We assessed potential Dpa in an vivo rat model ischemia/reperfusion underlying mechanisms. found that single intravenous treatment immediately before 30 minutes regional ischemia reduced necrosis following 120...
Background: Although transthoracic echocardiography (TTE) routinely establishes the diagnosis of double outlet right ventricle (DORV), it can be suboptimal for depicting exact ventricular septal defect (VSD) position, especially with respect to outflow tracts. Advanced imaging computed tomography angiography (CTA) help visualize structures and relationships not easily seen by echo. Using computer-aided design, we have ability create three-dimensional (3D) models intracardiac anatomy, which...
Infants awaiting paediatric heart transplantation (PHT) experience long waitlist duration and high mortality due to donor shortage. Using the United Network for Organ Sharing database, we explored if increasing donor-recipient weight ratio (DRWR) >2.0 (recommended cutoff) was associated with adverse outcomes.Between 2007 2020, 1392 infants received PHT. We divided cohort into 3 groups: A (DRWR ≤1.0, n = 239, 17%), B 1.0-2.0, 947, 68%), C >2.0, 206, 15%). Group characteristics PHT outcomes...
Congenital diaphragmatic hernia (CDH) presenting beyond the neonatal period is commonly perceived to be rare. With reported frequencies of 2.6% 20% all CDH, it may an overlooked cause mortality. Variable symptomatology makes its diagnosis challenging. We report sudden death a 3-month-old patient shortly after hospital discharge following congenital heart surgery. Autopsy findings associated patient’s demise with migrated abdominal contents in chest through Bochdalek defect. No indications...
Introduction Retrograde Autologous Priming (RAP) of cardiopulmonary bypass (CPB) circuits is an effective way to reduce prime volume, commonly through the transfer into separate reservoirs or circuit manipulation. We describe a simple and safe technique for RAP without need any modifications manipulations. Methods For this technique, roller pump ultrafiltration (UF) used. After adequate heparinization arterial cannulation, UF initiated slowly, removing effluent UF, replacing with patient’s...
End-stage congenital heart disease (CHD) in children with heterotaxy syndrome might necessitate a transplant (HTx). An HTx patients can be associated several technical (e.g. redo, systemic/pulmonary-venous/situs anomalies, pulmonary artery reconstruction) and extra-cardiac ciliary dyskinesia, infections, gastrointestinal) challenges. Our goal was to determine if is increased early or late risks.
This case report explores the successful use of Impella 5.5 (Abiomed Inc., Danvers, MA) device in a 22 kg, 0.89 body surface area (BSA) pediatric patient with longstanding dilated cardiomyopathy and elevated pulmonary vascular resistance. The article details selection, management, outcome demonstrating feasibility potential benefits as within population.
Paediatric heart transplantation in children who fail multistage palliation for hypoplastic left syndrome is associated with challenges related to immune, clinical or anatomic risk factors. We review current outcomes and factors survival following this challenging patient population.
Genetic syndromes (GSs) are often linked to congenital heart disease (CHD) and cardiomyopathy (CM). The effect of GSs on survival following pediatric transplant (HT) has not been well described. We aimed compare outcomes HT between children with a GS those without GS.