Deborah Kozik

ORCID: 0000-0002-0443-280X
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About
Contact & Profiles
Research Areas
  • Congenital Heart Disease Studies
  • Mechanical Circulatory Support Devices
  • Transplantation: Methods and Outcomes
  • Cardiac Structural Anomalies and Repair
  • Coronary Artery Anomalies
  • Organ Transplantation Techniques and Outcomes
  • Congenital Diaphragmatic Hernia Studies
  • Cardiac Valve Diseases and Treatments
  • Tracheal and airway disorders
  • Cardiovascular Conditions and Treatments
  • Cardiac pacing and defibrillation studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Diversity and Career in Medicine
  • Cardiac and Coronary Surgery Techniques
  • Cardiac Arrhythmias and Treatments
  • Vascular anomalies and interventions
  • Renal Transplantation Outcomes and Treatments
  • PARP inhibition in cancer therapy
  • Acute Kidney Injury Research
  • Surgical Simulation and Training
  • Acute Myocardial Infarction Research
  • Healthcare Policy and Management
  • Intestinal and Peritoneal Adhesions
  • Wireless Power Transfer Systems
  • Abdominal Surgery and Complications

Norton Hospital
2019-2024

Kosair Children's Hospital
2019-2024

University of Louisville
2016-2024

American Association for Thoracic Surgery
2024

Emory University
2024

Children's Healthcare of Atlanta
2024

University of Colorado Denver
2009-2023

Children's Hospital Colorado
2009-2023

Chestnut Hill College
2023

Norton Healthcare
2020

Abstract OBJECTIVES Heart transplantation for adult congenital heart disease is complicated and associated with challenging pretransplant support, long waiting high early post-transplant mortality. We explored if surgical medical advances allocation system changes have affected outcomes. METHODS From United Network Organ Sharing database, adults listed were queried. To explore practice outcome trends, patients divided into 4 eras (eras 1–3: nearly 3 equal periods from 1992 to 2018, era 4:...

10.1093/ejcts/ezae086 article EN European Journal of Cardio-Thoracic Surgery 2024-03-01

Erythropoietin is known to stimulate red cell production and has recently been shown protect the heart against injury from ischemia/reperfusion. However, it unknown whether darbepoetin alfa (Dpa), a long-acting analog of erythropoietin, can play protective role myocardial infarction. We assessed potential Dpa in an vivo rat model ischemia/reperfusion underlying mechanisms. found that single intravenous treatment immediately before 30 minutes regional ischemia reduced necrosis following 120...

10.1097/fjc.0b013e318040cf81 article EN Journal of Cardiovascular Pharmacology 2007-06-01

Background: Although transthoracic echocardiography (TTE) routinely establishes the diagnosis of double outlet right ventricle (DORV), it can be suboptimal for depicting exact ventricular septal defect (VSD) position, especially with respect to outflow tracts. Advanced imaging computed tomography angiography (CTA) help visualize structures and relationships not easily seen by echo. Using computer-aided design, we have ability create three-dimensional (3D) models intracardiac anatomy, which...

10.1177/2150135116651399 article EN World Journal for Pediatric and Congenital Heart Surgery 2016-06-29

Infants awaiting paediatric heart transplantation (PHT) experience long waitlist duration and high mortality due to donor shortage. Using the United Network for Organ Sharing database, we explored if increasing donor-recipient weight ratio (DRWR) >2.0 (recommended cutoff) was associated with adverse outcomes.Between 2007 2020, 1392 infants received PHT. We divided cohort into 3 groups: A (DRWR ≤1.0, n = 239, 17%), B 1.0-2.0, 947, 68%), C >2.0, 206, 15%). Group characteristics PHT outcomes...

10.1093/ejcts/ezad316 article EN European Journal of Cardio-Thoracic Surgery 2023-09-12

Congenital diaphragmatic hernia (CDH) presenting beyond the neonatal period is commonly perceived to be rare. With reported frequencies of 2.6% 20% all CDH, it may an overlooked cause mortality. Variable symptomatology makes its diagnosis challenging. We report sudden death a 3-month-old patient shortly after hospital discharge following congenital heart surgery. Autopsy findings associated patient’s demise with migrated abdominal contents in chest through Bochdalek defect. No indications...

10.1177/2150135112472348 article EN World Journal for Pediatric and Congenital Heart Surgery 2013-03-20

Introduction Retrograde Autologous Priming (RAP) of cardiopulmonary bypass (CPB) circuits is an effective way to reduce prime volume, commonly through the transfer into separate reservoirs or circuit manipulation. We describe a simple and safe technique for RAP without need any modifications manipulations. Methods For this technique, roller pump ultrafiltration (UF) used. After adequate heparinization arterial cannulation, UF initiated slowly, removing effluent UF, replacing with patient’s...

10.1177/02676591241239820 article EN Perfusion 2024-03-18

End-stage congenital heart disease (CHD) in children with heterotaxy syndrome might necessitate a transplant (HTx). An HTx patients can be associated several technical (e.g. redo, systemic/pulmonary-venous/situs anomalies, pulmonary artery reconstruction) and extra-cardiac ciliary dyskinesia, infections, gastrointestinal) challenges. Our goal was to determine if is increased early or late risks.

10.1093/ejcts/ezae204 article EN European Journal of Cardio-Thoracic Surgery 2024-05-24

This case report explores the successful use of Impella 5.5 (Abiomed Inc., Danvers, MA) device in a 22 kg, 0.89 body surface area (BSA) pediatric patient with longstanding dilated cardiomyopathy and elevated pulmonary vascular resistance. The article details selection, management, outcome demonstrating feasibility potential benefits as within population.

10.1097/mat.0000000000002256 article EN ASAIO Journal 2024-06-18

Paediatric heart transplantation in children who fail multistage palliation for hypoplastic left syndrome is associated with challenges related to immune, clinical or anatomic risk factors. We review current outcomes and factors survival following this challenging patient population.

10.1093/ejcts/ezae255 article EN European Journal of Cardio-Thoracic Surgery 2024-06-24

Genetic syndromes (GSs) are often linked to congenital heart disease (CHD) and cardiomyopathy (CM). The effect of GSs on survival following pediatric transplant (HT) has not been well described. We aimed compare outcomes HT between children with a GS those without GS.

10.1016/j.xjon.2024.05.016 article EN cc-by-nc-nd JTCVS Open 2024-06-27
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