A5072825952- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Pleural and Pulmonary Diseases
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Lung Cancer Research Studies
- Esophageal and GI Pathology
- Head and Neck Cancer Studies
- Global Cancer Incidence and Screening
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer Immunotherapy and Biomarkers
- Advanced Radiotherapy Techniques
- Neuroendocrine Tumor Research Advances
- Occupational and environmental lung diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Orthopedic Surgery and Rehabilitation
- Surgical Simulation and Training
- Diversity and Career in Medicine
- Pancreatic and Hepatic Oncology Research
- Intensive Care Unit Cognitive Disorders
- Cardiac pacing and defibrillation studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Immunotherapy and Immune Responses
Duke Medical Center
2016-2025
Cancer Institute (WIA)
2022-2025
Duke Cancer Institute
2012-2025
Duke University Hospital
2009-2024
Duke University
2015-2024
Alfred Health
2024
Memorial Sloan Kettering Cancer Center
2024
Society of Thoracic Surgeons
2020-2023
New York Proton Center
2023
English Heritage
2023
In Brief Objective: Using a national database, we asked whether video-assisted thoracoscopic surgery (VATS) lobectomy is beneficial in high-risk pulmonary patients. Background: Single-institution series demonstrated benefit of VATS over via thoracotomy poor function patients [FEV1 (forced expiratory volume 1 second) or DLCO (diffusion capacity the lung to carbon monoxide) <60% predicted]. Methods: The STS General Thoracic Database was queried for having undergone by either between 2000 and...
2][3][4] In 2011, it is estimated that 156,900 deaths (85,600 in men, 71,300 women) from lung cancer will occur the United States. 4Five-year survival rates for are only approximately 15.6%, partly because most patients have advanced-stage at initial diagnosis (http:// seer.cancer.gov/statfacts/html/lungb.html). 5hese facts, combined with success of screening improving outcomes cervical, colon, and breast cancers,
Purpose Data on optimal adjuvant therapy after complete resection of small-cell lung cancer (SCLC) are limited, and in particular, there have been no studies evaluating the role chemotherapy, with or without prophylactic cranial irradiation, relative to for stage T1-2N0M0 SCLC. This National Cancer Base analysis was performed determine potential benefits chemotherapy irradiation patients who undergo early-stage cancer. Patients Methods Overall survival pathologic SCLC underwent from 2003...
The NCCN Guidelines for Lung Cancer Screening recommend criteria selecting individuals screening and provide recommendations evaluation follow-up of lung nodules found during initial subsequent screening. These Insights focus on recent updates to the Screening.
Objective: The objective of this study was to compare the long-term survival open versus thoracoscopic (VATS) lobectomy for early stage non-small-cell lung cancer (NSCLC). Background: Data from national studies on VATS are limited. Methods: Outcomes patients who underwent clinical T1–2, N0, M0 NSCLC in National Cancer Base were evaluated using propensity score matching. Results: median follow-up 7114 lobectomies (5566 and 1548 VATS) 52.0 months. approach associated with a better 5-year when...
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Lung Cancer Screening provide recommendations selecting individuals lung cancer screening, and evaluation follow-up of nodules found during are intended to assist with clinical shared decision-making. These Insights focus on the major updates 2015 Screening, which include a revision recommendation from category 2B 2A one high-risk groups eligible screening. For low-dose CT lung, recommended slice width was revised table...
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Lung Cancer Screening provide criteria selecting individuals screening and offer recommendations evaluating managing lung nodules detected during initial subsequent annual screening. These Insights focus on recent updates to the Screening.
Abstract Purpose: To determine the immunologic effects of neoadjuvant chemotherapy plus ipilimumab in early-stage non–small cell lung cancer (NSCLC) patients. Experimental Design: This is a single-arm phased phase II study 24 treatment-naïve patients with stage IB–IIIA NSCLC. Patients received therapy consisting 3 cycles paclitaxel either cisplatin or carboplatin and included last 2 cycles. Results: Chemotherapy alone had little effect on immune parameters PBMCs. Profound CD28-dependent...
Background and Purpose— Neurocognitive decline occurs frequently after cardiac surgery persists in a significant number of patients. Magnesium is thought to provide neuroprotection by preservation cellular energy metabolism, blockade the N-methyl-D-aspartate receptor, diminution inflammatory response, inhibition platelet activation. We therefore hypothesized that intraoperative magnesium administration would decrease postoperative cognitive impairment. Methods— After approval Duke University...
Video-assisted thoracoscopic (VATS) lobectomy is increasingly accepted for the management of early-stage non-small cell lung cancer (NSCLC), but its role locally advanced cancers has not been as well characterized. We compared outcomes patients who received induction therapy followed by lobectomy, via VATS or thoracotomy. Perioperative complications and long-term survival all with NSCLC chemotherapy (ICT) (with without radiation therapy) from 1996–2012 were assessed using Kaplan–Meier Cox...
Purpose The prevalence of minimally invasive lung cancer surgery using video-assisted thoracic (VATS) has increased dramatically over the past decade, yet recent studies have suggested that lymph node evaluation during VATS lobectomy is inadequate. We hypothesized approach to for stage I resulted in a longitudinal outcome was not inferior thoracotomy. Patients and Methods > 65 years age who had undergone between 2002 2013 were analyzed within Society Thoracic Surgeons General Surgery...
Age is an important risk factor for morbidity after lung resection. This study was performed to identify specific factors complications resection in octogenarians.A prospective database containing patients aged 80 years or older, who underwent at a single institution between January 2000 and June 2009, reviewed. Preoperative, histopathologic, perioperative, outcome variables were assessed. Morbidity measured as patient having any perioperative event defined by the Society of Thoracic...
Lobectomy with an en-bloc chest wall resection is effective but potentially morbid treatment of lung cancer invading the wall. Minimally invasive approaches to lobectomy have reduced morbidity compared thoracotomy for early stage cancer, there insufficient evidence regarding feasibility hybrid thoracoscopic resection. We reviewed our experience and evaluate outcomes a approach using combined where rib spreading avoided. All patients who underwent ribs primary non-small cell from January 2000...