A5053966533- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- COVID-19 Clinical Research Studies
- COVID-19 diagnosis using AI
- Long-Term Effects of COVID-19
- Esophageal Cancer Research and Treatment
- Lung Cancer Research Studies
- Complementary and Alternative Medicine Studies
- Anesthesia and Pain Management
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Food Allergy and Anaphylaxis Research
- COVID-19 and healthcare impacts
- Radiomics and Machine Learning in Medical Imaging
- Machine Learning in Healthcare
- Head and Neck Cancer Studies
- Anesthesia and Sedative Agents
- Chronic Kidney Disease and Diabetes
- Pleural and Pulmonary Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Shoulder Injury and Treatment
- Acute Kidney Injury Research
- Medical Imaging and Pathology Studies
- Wireless Body Area Networks
- Respiratory viral infections research
Icahn School of Medicine at Mount Sinai
2020-2024
All India Institute of Medical Sciences
2010-2024
Central Council for Research in Homoeopathy
2018-2024
Jawaharlal Nehru Medical College
2024
Massachusetts General Hospital
2023
Harvard University
2023
McGill University
2023
Mount Sinai Hospital
2023
Jewish General Hospital
2023
Ganesh Shankar Vidyarthi Memorial Medical College
2018-2023
Machine learning models require large datasets that may be siloed across different health care institutions. studies focus on COVID-19 have been limited to single-hospital data, which limits model generalizability.
Objective: The objective of this study was to compare the long-term survival open versus thoracoscopic (VATS) lobectomy for early stage non-small-cell lung cancer (NSCLC). Background: Data from national studies on VATS are limited. Methods: Outcomes patients who underwent clinical T1–2, N0, M0 NSCLC in National Cancer Base were evaluated using propensity score matching. Results: median follow-up 7114 lobectomies (5566 and 1548 VATS) 52.0 months. approach associated with a better 5-year when...
Significance COVID-19 is taking a major toll on personal health, healthcare systems, and the global economy. With three betacoronavirus epidemics in less than 20 y, there an urgent need for therapies to combat new existing coronavirus outbreaks. Our analysis of clinical data from over 300,000 patients health systems demonstrates 50% reduced risk lithium, direct inhibitor glycogen synthase kinase-3 (GSK-3). We further show that GSK-3 essential phosphorylation SARS-CoV-2 nucleocapsid protein...
Objective: To compare outcomes after open versus thoracoscopic (VATS) lobectomy for clinical stage II (cN1) non-small-cell lung cancer (NSCLC). Background: There have been no published studies evaluating the impact of a VATS approach to N1 NSCLC on short-term and survival. Methods: Outcomes patients with T1-2, N1, M0 who underwent without induction therapy in National Cancer Data Base (2010–2012) were evaluated using multivariable Cox proportional hazards modeling propensity score-matched...
Multisystem inflammatory syndrome in children (MIS-C) presents with fever, inflammation and pathology of multiple organs individuals under 21 years age the weeks following severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. Although an autoimmune pathogenesis has been proposed, genes, pathways cell types causal to this new disease remain unknown. Here we perform RNA sequencing blood from patients MIS-C controls find disease-associated genes clustered a co-expression module annotated CD56
Acute kidney injury (AKI) is a known complication of COVID-19 and associated with an increased risk in-hospital mortality. Unbiased proteomics using biological specimens can lead to improved stratification discover pathophysiological mechanisms.
: Coronavirus disease 2019 (COVID-19) has so far affected over 41 million people globally. The limited supply of real-time reverse transcription-polymerase chain reaction (rRT-PCR) kits and reagents made meeting the rising demand for increased testing incompetent, worldwide. A highly sensitive specific antigen-based rapid diagnostic test (RDT) is need hour. objective this study was to evaluate performance a chromatographic immunoassay-based (index test) compared with clinical reference...
ABSTRACT Machine learning (ML) models require large datasets which may be siloed across different healthcare institutions. Using federated learning, a ML technique that avoids locally aggregating raw clinical data multiple institutions, we predict mortality within seven days in hospitalized COVID-19 patients. Patient was collected from Electronic Health Records (EHRs) five hospitals the Mount Sinai System (MSHS). Logistic Regression with L1 regularization (LASSO) and Multilayer Perceptron...
Sodicity is a critical stress that significantly affects the yield and productivity of wheat. This can result in range physiological, biochemical, molecular responses plants, which hinder their overall health potential. Understanding these key to developing salt-tolerant wheat (Triticum aestivum L.) varieties. The present study was carried out during 2022–23 2023–24 at ICAR-Central Soil Salinity Research Institute, Karnal, Haryana population 195 recombinant inbred lines (RILs) (HD2851 ×...
Background: Dyslipidaemia, the derangement of one or many lipoproteins is a major cause cardiovascular events, causing 2.6 million deaths per year globally.
Nasopharyngeal and oropharyngeal swab (NPS OPS) collection is widely accepted as the preferred method for obtaining respiratory samples. However, it has certain disadvantages which may be overcome by gargling. The primary objective of this study was to assess agreement between gargle lavage an appropriate sample detection SARS-CoV-2. secondary patient acceptability two sampling methods.It a cross-sectional done at tertiary care hospital in New Delhi, India, on 50 confirmed COVID-19 patients....
Abstract The coronaviruses responsible for severe acute respiratory syndrome (SARS-CoV), COVID-19 (SARS-CoV-2), Middle East (MERS-CoV), and other coronavirus infections express a nucleocapsid protein (N) that is essential viral replication, transcription, virion assembly. Phosphorylation of N from SARS-CoV by glycogen synthase kinase 3 (GSK-3) required its function inhibition GSK-3 with lithium impairs phosphorylation, replication. Here we report the SARS-CoV-2 contains consensus sequences...
Telehealth systems benefit from the rapid growth of mobile communication technology for measuring physiological signals. Development and validation a tablet PC enabled noninvasive body sensor system rural telehealth application are discussed in this paper. This includes real time continuous collection parameters (blood pressure, pulse rate, temperature) fall detection patient with help unit wireless transmission acquired information to handled by medical staff Primary Health Center (PHC)....
Background and objectives: Acute encephalitis syndrome is a health burden to populous country like India. It characterized by sudden onset of fever, altered sensorium with or without seizures, irritability, abnormal behaviour, unconsciousness. This study aims augment further evidence on the effects add-on homeopathic treatment in reducing mortality morbidity children. Methods: comparative retrospective included children hospitalized acute between July 2016 December 2016. We compared...
Bronchopulmonary sequestration represents a spectrum of abnormalities.One these abnormalities is an aberrant systemic arterial supply to normal lung with no bronchial sequestration.These lesions were originally classified by Pryce as type 1.Most patients are asymptomatic but time, many develop localized pulmonary hypertension, hemoptysis, and eventually high output cardiac failure.Multidetector computed tomography (MDCT) plays important role in the diagnosis planning definitive treatment...
Abstract Aims Clinical scoring systems for pulmonary embolism (PE) screening have low specificity and contribute to computed tomography angiogram (CTPA) overuse. We assessed whether deep learning models using an existing routinely collected data modality, electrocardiogram (ECG) waveforms, can increase PE detection. Methods results create a retrospective cohort of 21 183 patients at moderate- high suspicion associate 23 793 CTPAs (10.0% PE-positive) with 320 746 ECGs encounter-level clinical...
Acid-reducing drugs can cause increased growth of microbes, including fungus, because high gastric pH. Our purpose was to evaluate the occurrence mycotic infection in patients with duodenal ulcer on anti-ulcer therapy and compare effects cimetidine, famotidine, omeprazole. Eighty (62 males 18 female patients, 16-65 years old) were evaluated for before after 6 weeks (cimetidine, 20 patients; 40 omeprazole, patients). Mycotic diagnosed by endoscopic biopsy from edge subjected smear, culture,...
Abstract Multisystem inflammatory syndrome in children (MIS-C) presents with fever, inflammation and multiple organ involvement individuals under 21 years following severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. To identify genes, pathways cell types driving MIS-C, we sequenced the blood transcriptomes of MIS-C cases, pediatric cases disease 2019, healthy controls. We define a transcriptional signature partially shared response to SARS-CoV-2 infection Kawasaki disease,...