Konrad A. Szawan
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac Imaging and Diagnostics
- Neurosurgical Procedures and Complications
- Cardiac Structural Anomalies and Repair
- Cardiac Health and Mental Health
- Neurological and metabolic disorders
- Electroconvulsive Therapy Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Biomedical and Chemical Research
- Cardiovascular Issues in Pregnancy
- Psychology, Coaching, and Therapy
- Pericarditis and Cardiac Tamponade
- Intracerebral and Subarachnoid Hemorrhage Research
- Mitochondrial Function and Pathology
- Cardiac tumors and thrombi
- COVID-19 Clinical Research Studies
- Spinal Fractures and Fixation Techniques
- Cardiac Arrest and Resuscitation
- Electrolyte and hormonal disorders
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Acute Ischemic Stroke Management
- Alcoholism and Thiamine Deficiency
- Adrenal and Paraganglionic Tumors
University Hospital of Zurich
2018-2024
University of Zurich
2023-2024
Zurich Heart House
2020
Abstract Aims We aimed to evaluate the frequency, clinical features, and prognostic implications of cardiac arrest (CA) in takotsubo syndrome (TTS). Methods results reviewed records patients with CA known heart rhythm from International Takotsubo Registry. The main outcomes were 60-day 5-year mortality. In addition, predictors mortality during acute TTS phase assessed. Of 2098 patients, 103 included. Compared without CA, more likely be younger, male, have apical TTS, atrial fibrillation...
Background Clinical characteristics and outcomes of takotsubo syndrome (TTS) patients with malignancy have not been fully elucidated. This study sought to explore differences in clinical investigate short- long-term TTS or without malignancy. Methods Results were enrolled from the International Takotsubo Registry. The cohort was divided into assess mortality. A subanalysis performed comparing mortality between a subset acute coronary (ACS) Malignancy observed 16.6% 1604 patients. Patients...
Abstract Aims Takotsubo syndrome (TTS) is an acute heart failure syndrome, which shares many features with coronary (ACS). Although TTS was initially described angiographically normal arteries, smaller studies recently indicated a potential coexistence of artery disease (CAD) in patients. This study aimed to determine the coexistence, features, and prognostic role CAD large cohort patients TTS. Methods results Coronary anatomy were studied diagnosed Inclusion criteria compliance...
Journal Article Cardiac biomarkers for diagnosing Takotsubo syndrome Get access Victor Schweiger, Schweiger Department of Cardiology, University Heart Center, Hospital Zurich, Rämistrasse 100, 8091 Switzerland Search other works by this author on: Oxford Academic PubMed Google Scholar Davide Di Vece, Vece First Clinic Internal Medicine, Genoa, ItalyInternal Medicine B, Greifswald, Germany Victoria L Cammann, Cammann Iva Koleva, Koleva Michael Würdinger, Würdinger Thomas Gilhofer, Gilhofer...
Takotsubo syndrome (TTS) is characterized by acute left ventricular dysfunction, which can contribute to intraventricular thrombus and embolism. Still, prevalence clinical impact of formation embolic events on outcome TTS patients remain unclear. This study aimed investigate features outcomes with without or Additionally, factors associated embolism, as well predictors for mortality, were identified. Approach Results: enrolled in the International Registry at 28 centers Australia, Europe,...
Takotsubo syndrome (TTS) is associated with a substantial rate of adverse events. We sought to design machine learning (ML)-based model predict the risk in-hospital death and perform clustering TTS patients identify different profiles.
Background Atrial fibrillation (AF) is a major risk factor for mortality. The prevalence, clinical correlates, and prognostic impact of AF in Takotsubo syndrome (TTS) have not yet been investigated large patient cohort. This study aimed to investigate the patients with TTS. Methods Results Patients TTS were enrolled from International Registry, which multinational network 26 participating centers Europe United States. dichotomized according presence or absence at time admission. Of 1584 TTS,...
The clinical relevance of cardiac troponin (cTn) elevation in takotsubo syndrome (TTS) remains uncertain. present study sought to investigate the role elevations mortality prediction patients with Takotsubo (TTS).
Background Left ventricular (LV) recovery in takotsubo syndrome (TTS) occurs over a wide-ranging interval, varying from hours to weeks. We sought investigate the clinical predictors and prognostic impact of time for TTS patients. Methods Results patients International Takotsubo Registry were included this study. Cut-off early LV was determined be 10 days after acute event. Multivariable logistic regression used assess factors associated with absence recovery. In-hospital outcomes 1-year...
Abstract Cardiac alterations are frequently observed after acute neurological disorders. Takotsubo syndrome (TTS) represents an heart failure and is increasingly recognized as part of the spectrum cardiac complications A systematic investigation TTS patients with disorders has not been conducted yet. The aim study was to expand insights regarding disease entities triggering investigate clinical profile outcomes primary International Registry observational multicenter collaborative effort 45...
Ethnic disparities have been reported in cardiovascular disease. However, ethnic takotsubo syndrome (TTS) remain elusive. This study assessed differences clinical characteristics between Japanese and European TTS patients determined the impact of ethnicity on in-hospital outcomes.TTS Japan were enrolled from 10 hospitals Europe 32 participating International Takotsubo Registry. Clinical outcomes compared patients.A total 503 1670 included. older (72.6 ± 11.4 years vs. 68.0 12.0 years; p <...
Abstract Aims Acute pulmonary disorders are known physical triggers of takotsubo syndrome (TTS). This study aimed to investigate prevalence acute in patients with TTS and their impact on outcomes. Methods results Patients were enrolled from the International Takotsubo Registry screened for triggering factors comorbidities. categorized into three groups (acute trigger, chronic lung disease, no disease) compare clinical characteristics Of 1670 included TTS, 123 (7%) identified an 194 (12%) had...
Background: Takotsubo syndrome (TTS) and spontaneous coronary artery dissection (SCAD) are now increasingly recognized. Both conditions predominantly affect females; however, the exact pathophysiology remains unclear. Large multi-center databases can help elucidate underlying mechanism optimize treatments to improve outcomes by allowing us compare features of patients with TTS SCAD. Methods: were enrolled from International Registry compared SCAD Canadian Spontaneous Coronary Artery...
MINOCA and Takotsubo in acute coronary syndromes 961Conclusion: In our study, about 1 every 10 patients with TC have atrial fibrillation, which was associated worse short-term outcomes.AF higher age, CKD, lower LVEF a rate of in-hospital ventricular tachycardia complete AV block.Although there no association mortality, significant correlation between AF the composite endpoint CS, malignant arrhythmias mortality.There were differences on long-term endpoints.Adequate monitoring should be given...
Abstract Background/Introduction Cardiac biomarker elevations are frequently observed in Takotsubo syndrome (TTS). The clinical relevance of cardiac troponin (cTn) TTS patients remains uncertain and threshold values indicating clinically relevant myocardial injury unknown. Purpose This study sought to investigate the role cTn mortality prediction with TTS. Methods A total 2,938 enrolled prospective International (InterTAK) Registry from January 2011 February 2020 available data on baseline...