Michael Neuhaus
- Takotsubo Cardiomyopathy and Associated Phenomena
- Facial Trauma and Fracture Management
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Cleft Lip and Palate Research
- Neurosurgical Procedures and Complications
- Dental Implant Techniques and Outcomes
- Craniofacial Disorders and Treatments
- Facial Nerve Paralysis Treatment and Research
- Anatomy and Medical Technology
- Dental Radiography and Imaging
- Tracheal and airway disorders
- Head and Neck Cancer Studies
- Telomeres, Telomerase, and Senescence
- Temporomandibular Joint Disorders
- Reconstructive Surgery and Microvascular Techniques
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Peptidase Inhibition and Analysis
- Reconstructive Facial Surgery Techniques
- Spinal Fractures and Fixation Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Head and Neck Surgical Oncology
- Surgical Simulation and Training
- Sinusitis and nasal conditions
Medizinische Hochschule Hannover
2011-2025
Kantonsspital Frauenfeld
2019-2024
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
2024
University Hospital Leipzig
2021-2023
Leipzig University
2021-2023
Universität Innsbruck
2012-2014
Kantonsspital Baden
2006-2013
Austrian Academy of Sciences
2010-2013
Abstract Aims Takotsubo syndrome (TTS) is an acute heart failure syndrome, which shares many features with coronary (ACS). Although TTS was initially described angiographically normal arteries, smaller studies recently indicated a potential coexistence of artery disease (CAD) in patients. This study aimed to determine the coexistence, features, and prognostic role CAD large cohort patients TTS. Methods results Coronary anatomy were studied diagnosed Inclusion criteria compliance...
Journal Article Cardiac biomarkers for diagnosing Takotsubo syndrome Get access Victor Schweiger, Schweiger Department of Cardiology, University Heart Center, Hospital Zurich, Rämistrasse 100, 8091 Switzerland Search other works by this author on: Oxford Academic PubMed Google Scholar Davide Di Vece, Vece First Clinic Internal Medicine, Genoa, ItalyInternal Medicine B, Greifswald, Germany Victoria L Cammann, Cammann Iva Koleva, Koleva Michael Würdinger, Würdinger Thomas Gilhofer, Gilhofer...
Abstract Background Cellular senescence can be induced by a variety of extrinsic stimuli, and sustained exposure to sunlight is key factor in photoaging the skin. Accordingly, irradiation skin fibroblasts UVB light triggers cellular senescence, which thought contribute aging, although molecular mechanisms are incompletely understood. Here, we addressed underlying human diploid fibroblasts. Results We observed parallel activation p53/p21 WAF1 p16 INK4a /pRb pathways. Using genome-wide...
Summary Methionine restriction (MetR) extends lifespan in animal models including rodents. Using human diploid fibroblasts ( HDF ), we report here that MetR significantly their replicative lifespan, thereby postponing cellular senescence. decreased activity of mitochondrial complex IV and diminished the accumulation reactive oxygen species. Lifespan extension was accompanied by a significant decrease levels subunits , but also I, which due to translation rate several mt DNA ‐encoded...
Takotsubo syndrome (TTS) is characterized by acute left ventricular dysfunction, which can contribute to intraventricular thrombus and embolism. Still, prevalence clinical impact of formation embolic events on outcome TTS patients remain unclear. This study aimed investigate features outcomes with without or Additionally, factors associated embolism, as well predictors for mortality, were identified. Approach Results: enrolled in the International Registry at 28 centers Australia, Europe,...
Abstract Objectives The aim of the current study was to evaluate potential differences in accuracy mandibular reconstruction and long-term stability, with respect different reconstructive procedures. Methods In total, 42 patients who had undergone primary segmental resection immediate alloplastic reconstruction, either manually pre-bent or patient-specific plates (PSMRP), were included this study. Mandibular dimensions, terms six clinically relevant distances (capitulum [most lateral...
Takotsubo syndrome (TTS) is associated with a substantial rate of adverse events. We sought to design machine learning (ML)-based model predict the risk in-hospital death and perform clustering TTS patients identify different profiles.
The clinical relevance of cardiac troponin (cTn) elevation in takotsubo syndrome (TTS) remains uncertain. present study sought to investigate the role elevations mortality prediction patients with Takotsubo (TTS).
Background Atrial fibrillation (AF) is a major risk factor for mortality. The prevalence, clinical correlates, and prognostic impact of AF in Takotsubo syndrome (TTS) have not yet been investigated large patient cohort. This study aimed to investigate the patients with TTS. Methods Results Patients TTS were enrolled from International Registry, which multinational network 26 participating centers Europe United States. dichotomized according presence or absence at time admission. Of 1584 TTS,...
Due to a significant shortage of healthcare staff, medical facilities are increasingly challenged by the need deploy current staff more intensively, which can lead complications for patients and staff. Digital surgical assistance systems that track all instruments used in procedures make contribution relieving load on increasing efficiency, avoiding errors improving hygiene. data safety concerns, laborious annotation complexity scenes, as well increase prediction accuracy, provision...
Abstract Cardiac alterations are frequently observed after acute neurological disorders. Takotsubo syndrome (TTS) represents an heart failure and is increasingly recognized as part of the spectrum cardiac complications A systematic investigation TTS patients with disorders has not been conducted yet. The aim study was to expand insights regarding disease entities triggering investigate clinical profile outcomes primary International Registry observational multicenter collaborative effort 45...
Three-dimensional facial scans have recently begun to play an increasingly important role in the peri-therapeutic management of oral and maxillofacial head neck surgery cases. Face scan images can be generated by optical scanners utilizing line-laser, stereophotography, or structured light modalities, as well from volumetric data: for example, cone beam computed tomography (CBCT). This study aimed evaluate whether two low-cost procedures creation three-dimensional face were capable producing...
Ethnic disparities have been reported in cardiovascular disease. However, ethnic takotsubo syndrome (TTS) remain elusive. This study assessed differences clinical characteristics between Japanese and European TTS patients determined the impact of ethnicity on in-hospital outcomes.TTS Japan were enrolled from 10 hospitals Europe 32 participating International Takotsubo Registry. Clinical outcomes compared patients.A total 503 1670 included. older (72.6 ± 11.4 years vs. 68.0 12.0 years; p <...
Abstract Aims Acute pulmonary disorders are known physical triggers of takotsubo syndrome (TTS). This study aimed to investigate prevalence acute in patients with TTS and their impact on outcomes. Methods results Patients were enrolled from the International Takotsubo Registry screened for triggering factors comorbidities. categorized into three groups (acute trigger, chronic lung disease, no disease) compare clinical characteristics Of 1670 included TTS, 123 (7%) identified an 194 (12%) had...
Availability of methionine is known to modulate the rate aging in model organisms, best illustrated by observation that dietary restriction extends lifespan rodents. However, underlying mechanisms are incompletely understood. In eukaryotic cells, can be converted cysteine through reverse transsulfuration pathway thereby modulating intracellular availability. Whereas previous results obtained yeast and fruit flies suggest alterations aging, it not whether this function conserved evolution....
Congenital mandibular hypoplasia (CMH) remains challenging because of the underlying combined hard and soft tissue deficiency. Treatment options include craniofacial distraction, orthognathic surgery, autologous grafts, although latter produces inadequate results after distraction grafting. Unsatisfactory long-term stability may cause relapse, necessitating reoperation.We investigated feasibility using alloplastic total joint replacement (TJR) in growing young adult CMH patients. The primary...
Abstract Purpose The oral cavity and, in particular, potential foci might pose a risk of periprosthetic joint infection (PJI). aim this cohort study was to determine whether practical preoperative dental screening would reduce the prevalence early PJI first month after surgery. Methods Patients attending specialized endoprosthesis implantation clinic between 2018 and 2022 were recruited. Two groups examined. test group consisted patients 2020 who referred their family dentist using...