A5065995165- Asymmetric Hydrogenation and Catalysis
- Catalytic Cross-Coupling Reactions
- Chemical Synthesis and Analysis
- Catalytic C–H Functionalization Methods
- Nanomaterials for catalytic reactions
- Catalytic Alkyne Reactions
- Multicomponent Synthesis of Heterocycles
- Chemical Synthesis and Reactions
- Asymmetric Synthesis and Catalysis
- Bacterial biofilms and quorum sensing
- Antibiotic Resistance in Bacteria
- Catalysis and Hydrodesulfurization Studies
- Radical Photochemical Reactions
- Organoboron and organosilicon chemistry
- Click Chemistry and Applications
- Coordination Chemistry and Organometallics
- Covalent Organic Framework Applications
- Mesoporous Materials and Catalysis
- Synthesis of Organic Compounds
- Antifungal resistance and susceptibility
- Antimicrobial Peptides and Activities
- Synthesis and Catalytic Reactions
- Fluorine in Organic Chemistry
- Synthesis of heterocyclic compounds
- Neuropeptides and Animal Physiology
Centro Regional de Selección y Reproducción Animal
2023
Universidad Autónoma de Madrid
2019-2021
MODUL University Dubai
2020
University College Cork
2015-2019
Hospital de La Ribera
2017
University of Alicante
2010-2016
National University of Ireland
2016
Irkutsk State University
2015
Instituto de Química Orgánica General
2014
Ministério Público
2013
Various impregnated metallic salts on magnetite have been prepared, including cobalt, nickel, copper, ruthenium, and palladium salts, as well a bimetallic palladium-copper derivative. Impregnated ruthenium catalyst is versatile, inexpensive, simple system for the selective N-monoalkylation of amino derivatives with poor nucleophilic character, such aromatic heteroaromatic amines, sulfonamides, sulfinamides, nitroarenes, using in all cases alcohols initial source electrophile, through...
A new protocol for the Ullmann-type arylation process of different aromatic heterocycles without any transition-metal catalyst, implying use a combination an excess potassium hydroxide and dimethyl sulfoxide, is described. The reaction can be performed between broad range starting nucleophiles including phenol, alcohols, amines, nitrogen-containing five-membered systems such as pyrazoles, imidazoles, indoles, amides with haloarenes, iodide bromide derivatives giving best results, possible...
Manganese catalysed C–H activation has emerged as a promising green alternative to transition metal mediated processes.
New impregnated platinum on magnetite catalyst has been prepared, characterized and used for the hydrosilylation of different alkynes. The showed a wide reaction scope, allowing its use functionalized alkynes, localized triple bonds, silane reagents. is selective case diynes, obtaining desired mono- or dihydrosilylation processes. with disilane reagents lead to incorporation two alkyne units final product. easily prepared handled, avoiding expensive difficult handle organic ligands, it could...
We bring together the mature, yet poorly-understood, subject of heterogeneous catalysis with rapidly expanding area Direct Arylation, a view towards acceleration catalyst design and understanding behaviour.
A new impregnated iridium on magnetite catalyst has been prepared, characterized, used and recycled, up to ten times with practically the same activity, for first practical cross-alkylation of primary alcohols. The showed a wide reaction scope, is easy prepare handle, it could be removed from medium just by magnetic sequestering.
Abstract The impregnated copper on magnetite catalyst is a versatile system for the synthesis of imines starting from alcohols and amines. This does not require any type expensive difficult to handle organic ligand or typical transition metals, provides excellent yields achievable under mild reaction conditions. Moreover, very easy remove medium by simply using magnet. one‐pot process dehydrogenation in presence aniline followed aqueous hydrolysis gave pure yields. In addition amines,...
Abstract The most useful strategies for the alkylation of allylic systems are related to Tsuji–Trost reaction or use different Lewis acids. Herein we report a photocatalytic approach allylation variety nucleophiles, such as heteroarenes, amines and alcohols. This method is compatible with large pyrroles indoles, containing substituents electron-withdrawing electron-donating groups, unprotected nitrogen atoms bromo derivatives. Moreover, this methodology enables chromoselective synthesis Z -...
A simple protocol for the borylation with use of impregnated copper on magnetite is described. The reactions showed a very broad scope and all type olefins could be used similar results. catalyst easily removed by magnet it reused several times, showing activity.
The contribution of the gut microbiota to metabolism cholesterol is not well understood. In this study, we identify 21 fosmid clones from a human microbiome metagenomic library that, when expressed in Escherichia coli, produce halos on LB agar supplemented with 0.01% (w/v) (LBC agar). Analysis 14 these revealed that they all share fragment DNA homology genome Bacteroides vulgatus. gene responsible for halo production LBC agar, named choA, was identified as an N-acyltransferase known acylated...
Multicomponent azide–alkyne cycloaddition catalyzed by impregnated bimetallic nickel and copper on magnetite.
Faced with the continued emergence of antibiotic resistance to all known classes antibiotics, a paradigm shift in approaches towards antifungal therapeutics is required. Well characterised broad spectrum bacterial and fungal pathogens, biofilms are key factor limiting effectiveness conventional antibiotics. Therefore, such as small molecules that prevent or disrupt biofilm formation would render pathogens susceptible clearance by existing drugs. This first report describing effect...
ABSTRACT A rapid decline in the development of new antimicrobial therapeutics has coincided with emergence and more aggressive multidrug-resistant pathogens. Pathogens are protected from antibiotic activity by their ability to enter an aggregative biofilm state. Therefore, disrupting this process pathogens is a key strategy for next-generation antimicrobials. Here, we present suite compounds, based on Pseudomonas aeruginosa 2-heptyl-4(1H)-quinolone (HHQ) core quinolone interkingdom signal...
Abstract Die Alkylierung von Ketonen ist Teil des Grundstudiums der Chemie. In vielen Fällen führt diese Umwandlung zu einem neuen stereogenen Zentrum. Allerdings täuscht die scheinbare Einfachheit über eine Reihe Schwierigkeiten hinweg, so groß sind, dass allgemeine Methode für direkte asymmetrische bisher unerreicht ist. Trotz Weiterentwicklung Organo‐ und Übergangsmetallkatalyse liefert keine beiden adäquate Lösung. Sogar Anwendung eines effizienten allgemein verwendbaren...
Copper-impregnated magnetite is a versatile heterogeneous catalytic system for the synthesis of 1,3-diynes by homocoupling terminal alkynes. This catalyst does not require use pressurized oxygen as oxidant and it need solvent or harsh conditions to give expected products. Moreover, can be removed from reaction medium simply using magnet. The occurs at lowest copper loading reported any catalyst.
Swarming motility inhibition in<italic>Bacillus atrophaeus</italic>.
The ‘perfect storm’ of increasing bacterial antibiotic resistance and a decline in the discovery new antibiotics, has made it necessary to search for innovative strategies treat infections.