- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiac tumors and thrombi
- Aortic aneurysm repair treatments
- Pulmonary Hypertension Research and Treatments
- Mechanical Circulatory Support Devices
- Renal cell carcinoma treatment
- Cardiac Ischemia and Reperfusion
- Trauma Management and Diagnosis
- Cerebrovascular and Carotid Artery Diseases
- Vasculitis and related conditions
- Coronary Artery Anomalies
- Cardiovascular and Diving-Related Complications
- Cardiac pacing and defibrillation studies
- Cardiac Arrest and Resuscitation
- Venous Thromboembolism Diagnosis and Management
- Renal and Vascular Pathologies
- Blood transfusion and management
- Infectious Aortic and Vascular Conditions
- IgG4-Related and Inflammatory Diseases
University Hospital Hradec Králové
2005-2023
Charles University
2009-2023
Ocní klinika
1997-2010
Rutgers, The State University of New Jersey
2003
Centrum kardiovaskulární a transplantační chirurgie
1990
In patients after aortic valve surgery, the quality of life is hypothesized to be influenced by type procedure. A cross-sectional study on postoperative was carried out in valve-sparing surgery (with regards age patient), Ross procedure and mechanical replacement.Quality studied 139 divided into four groups (Y - at below 50 years, mean 36.2 years; O years over, 59.2 R procedure, 37.8 M replacement 39.2 years). SF-36 Short Form valve-specific questionnaires were mailed 6 months or later...
What's known on the subject? and What does study add? Surgical treatment of renal cell carcinoma (RCC) with tumour thrombus extending into right atrium remains, despite its complexity specific technical aspects, only radical therapeutic option. This single-centre study, unique in size for this rare condition, reports early late results over a period 18 years. All patients were operated using standardised protocol use cardiopulmonary bypass deep hypothermic circulatory arrest. Overall...
Objective: The aim of this study was to monitor and compare metabolic changes in the skeletal muscle during coronary artery bypass grafting surgery with without cardiopulmonary (CPB) by means interstitial microdialysis. Glucose, lactate, pyruvate glycerol were assessed as markers basic metabolism tissue perfusion. Methods: Twenty patients undergoing surgical myocardial revascularization enrolled pilot study. Ten operated on CPB (group A, off-pump) 10 using normothermic B, on-pump)....
Background Renal cell carcinoma (RCC) with tumor thrombus extension into the right atrium (level IV) is a rare life-threatening clinical condition that can only be managed by means of combined urological and cardiac surgical approach. The early late outcomes this radical treatment were analyzed in large single-institution series over period 30 years. Methods In 37 patients RCC intracardiac extension, nephrectomy was performed followed extraction intracaval under direct visual control during...
Background The aim of this study was to analyze short- and mid-term results after aortic valve (AV) repair with particular regard the impact cuspidity (bicuspid versus tricuspid valve). Methods One hundred patients regurgitation (AR) undergoing between November 2007 October 2012 were included in study. Sixty had bicuspid AV (BAV group; 11 females) 40 (TAV 13 females). AR > grade 2 present 47 (78%) BAV 35 (88%) TAV group. Follow-up complete 100% median 25 months. Results Isolated performed 27...
Coronary artery bypass grafting resulted in a fatal outcome two patients with unsuspected cardiac amyloidosis. Despite preoperative symptoms of myocardial ischemia, each case represented different pathophysiological combination amyloidosis and coronary disease. Pitfalls preventing correct diagnosis possible patterns treatment are discussed.
From September 1994 to December 2002, 6,274 cardiosurgery operations were performed at the Department of Cardiac Surgery, University Hospital, Hradec Králové, Czech Republic. Intraaortic balloon counterpulsation (IABP) was applied in 192 cases (3.1%). this group counterpulsated patients 103 successfully treated (53.6%); 89 (46.4%) died from surgical procedure (30-day mortality rate). In 5 (2.6%) 192, IABP introduced before operation. Ischemic changes limb observed 11 (5.7%). Significant...
Renal cell carcinoma with a tumour thrombus extending into the right heart chambers necessitates extensive combined urological and cardiac surgery. Maximum safety exactness in extirpation of caval intracardiac is achieved under deep hypothermic circulatory arrest, at price its non-physiological burden time constraints. We propose simple surgical manoeuvre enabling selective arch perfusion allowing for milder hypothermia liberal interval arrest. On routine cardiopulmonary bypass via median...
Záchovné operace a plastiky aortální chlopně představují možnost chirurgicky obnovit kompetenci nedomykavé vyhnout se rizikům, která provázejí nemocné v případě náhrady chlopně. Úspěšné provedení rekonstrukce vyžaduje plné porozumění statické i dynamické geometrii aortálního kořene. Aortální regurgitace vychází z malpozice patologicky změněných chlopenních cípů, současně je velmi často spojena s dilatačním postižením kořene vzestupné aorty. Technika chirurgických intervencí pro nedomykavost...
Cíl: Zjistit krátkodobé až střednědobé výsledky záchovných operací a plastik aortální chlopně.Metodika: V období od 11/2007 do 6/2009 bylo na Kardiochirurgické klinice Fakultní nemocnice v Hradci Králové provedeno celkem 28 chlopně. Průměrný věk operovaných byl 51 ± 15 let. stupeň regurgitace před 3,5 0,8, ejekční frakce (EF) 54 10 %, end-diastolický rozměr levé komory (EDD) 60 mm. Funkční způsobená změnou geometrie aortálního kořene byla zjištěna u 16 pacientů. Prolaps cípu diagnostikován...
Isolated thoracic aortitis (ITA) is a newly-defined pathological entity with still-unknown etiopathology and some potential relationship to IgG4-related systemic disease. We investigated patients on whom the ascending aorta was operated identify clinical histopathological features of ITA its disease.Two hundred fifty-one underwent replacement aorta. Retrospective review all histological reports done noninfectious aortitis. Immunohistochemical analysis resected specimens performed in cases.We...
This study was done to compare the protective effect of blood and crystalloid cardioplegia in patients with left ventricular dysfunction undergoing coronary artery bypass grafting (CABG). Sixty consecutive ejection fraction < 35 % scheduled for CABG use cardiopulmonary without additional procedures were randomly divided into two groups. In first group we used cold cardioplegia, second both delivered only ortogradly. We measured hemodynamic data early hours after operation, enzyme release...
The very large patient (weight 142 kg, height 197 cm, body surface 2.76 m2) was referred to acute operation with dissecting type A ascending aortic aneurysm. calculated blood flow 6.63 l/min. To anticipate potential difficulties perfusion and oxygenation two oxygenators connected in parallel were incorporated into the circuit. Bentall procedure ACB RCA performed. uneventful. Bypass time 259 minutes, cross clamp 141 circulatory arrest 7 minutes. highest gas 2.6 l/min maximum FiO2 0.42. use of...
We present three cases of pneumopericardium following blunt chest trauma injury. All patients were victims road traffic accidents. had multiple associated injuries and was found as the additional finding. Pneumopericardium treated conservatively with thoracic drains placement observation. Transesophageal echocardiography used a method choice for exclusion cardiac air tamponade. survived.
Thoracic electrical bioimpedance cardiography is a non-invasive, continuous and low-cost method of estimation cardiac output other haemodynamic parameters. Though subject to technological refinement controversial opinions exist on its validity in subsets critically ill patients, patients with heart disease or after surgery. A comparison study between thermodilution (TD) (TEB) was performed 28 undergoing elective surgery (CABG, aortic mitral valve replacement combined procedures). 128 pairs...
The internal mammary artery (IMA) ranks among excellent, widely used conduits for surgical coronary revascularization. Its harvesting and its using may cause other technical problems complications increase postoperative bleeding from wound surface after the IMA with significantly greater incidence of blood transfusion. aim this study was to get know how much it increases losses if local application aprotinin (to into pericardial cavity) can reduce them thus decrease number transfusions.In...
The intracoronary administration of autologous bone marrow cells (BMCs) has been shown to improve the left ventricle function in course acute myocardial infarction. Therefore we have started a clinical trial using transplantation BMCs phase aim our study is assess feasibility and safety this procedure, effect on these patients. We describe first experience two patients with infarction reperfused direct stenting. aspiration from sternum provided sufficient amount for transplantation. No...
vod: Clem prce je zhodnocen krtkodobch a stedndobch vsledk plastik aortln chlopn.Metodika: V obdob od listopadu 2007 do jna 2012 bylo na Kardiochirurgick klinice FN Hradec Krlov operovno celkem 100 pacient s regurgitac, u kterch byla provedena plastika chlopn (24 en; prmrn vk 50,3 roku; rozmez 23-77 let). edest mlo bikuspidln chlope 82 regurgitaci (AR) > 2.Vzestupn aorta/koen aorty byly nahrazeny 67 pacient. Plastika cp 74 48 nemocnch nutn stabilizovat anulus. Dlka sledovn se pohybovala 1 59...