- Healthcare Policy and Management
- Global Health Care Issues
- Primary Care and Health Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Disease Management Strategies
- Diabetes Management and Research
- Education, Healthcare and Sociology Research
- Diabetes Management and Education
- Health disparities and outcomes
- Social and Educational Sciences
- Bone health and osteoporosis research
- Radiation Dose and Imaging
- Hip and Femur Fractures
- Musculoskeletal pain and rehabilitation
- Healthcare cost, quality, practices
- Diabetes Treatment and Management
- Retinal and Macular Surgery
- Medical Imaging and Analysis
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Promotion and Cardiovascular Prevention
- Efficiency Analysis Using DEA
- Cardiac Health and Mental Health
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Ocular Oncology and Treatments
- Workplace Health and Well-being
University of Southern Denmark
2016-2025
Tennessee Retina
2024
Odense University Hospital
2021
Danmarks Nationalbank
2020
Technical University of Denmark
2020
University Hospitals of Cleveland
2017
Case Western Reserve University
2017
Charité - Universitätsmedizin Berlin
2015
University of Pittsburgh
2015
Japan Center for Economic Research
2012-2013
The new Global Initiative for Obstructive Lung Disease (GOLD) stratification of chronic obstructive pulmonary disease (COPD) into categories A, B, C, and D is based on symptoms, level lung function, history exacerbations.To investigate the abilities this to predict clinical course COPD.Two similar population studies were performed in an area Copenhagen including 6,628 individuals with COPD.The patients monitored average period 4.3 years regarding COPD exacerbations, hospital admissions,...
To analyze the cost-effectiveness of shorter delays to treatment and increased thrombolysis rate as shown in PHANTOM-S (Prehospital Acute Neurological Treatment Optimization Medical Care Stroke) Study.In addition intermediate outcomes (time thrombolysis) rates, we registered all resource consequences intervention. The analyzed effects intervention were restricted distribution IV (IVT) administrations according time intervals. Intermediate extrapolated final numbers needed treat derived from...
The nucleotide sequence coding for the cytotoxic T-lymphocyte (CTL) protein perforin 1 (P1) has been determined and corresponding derived. Murine CTL cDNA libraries contained in vector lambda gt11 were screened by using a monospecific antiserum to purified P1. Three recombinant phages isolated their inserts sequenced. derived contains 554 amino acids displays, as expected, considerable homology with certain functional domains complement components C9, C8 alpha, beta, C7. identity of P1...
The aim of this prospective clinical study was to derive the absolute and relative costs cone beam CT (CBCT) panoramic imaging before removal an impacted mandibular third molar. Furthermore, aimed analyse influence different cost-setting scenarios on outcome incremental related surgery.
A randomized controlled trial (RCT) of stratified care demonstrated superior clinical outcomes and cost-effectiveness for low back pain (LBP) patients in UK primary care. This is the first study Europe, outside original study, to investigate efficacy compared with current practice non-specific LBP.The was a two-armed RCT. Danish LBP were (n = 169) or 164). Primary at 3- 12-months' follow-up Roland Morris Disability Questionnaire (RDMQ), patient-reported global change time off work. Secondary...
Background Chronic disease monitoring programs often adopt a one-size-fits-all approach that does not consider variation in need, potentially leading to excessive or insufficient support for patients at different risk levels. Machine learning (ML) developments offer new opportunities personalised medicine clinical practice. Objective To demonstrate the potential of ML guide resource allocation and tailored management, this study aims predict optimal testing interval blood glucose (HbA1c)...
Mixed remuneration schemes with capitation and fee-for-service (FFS) payments hold financial incentives to add patients the list provide services listed patients. However, as complex needs tend require longer consultations there is a risk of inequality in access if fees are not adjusted patient characteristics. In this paper, we assess natural experiment introducing additional for GPs high share (moderate scheme) certain geographical areas (intensive scheme). eligible complexity their...
This epidemiological study aimed to analyse economical and societal consequences in Denmark if CBCT is used routinely as a diagnostic method before removal of the mandibular third molar. Furthermore, aim was calculate excess cancer incidence from this practice.17 representative dental clinics regions were visited by two observers, who registered total number patients each clinic, removed molars patients' files together with age gender these patients. The data collected 2008 2014. year...
ABSTRACT Vertebral fractures (VFs) have been associated with future fractures, yet few studies evaluated whether this pertains to VFs available for identification on routine radiological imaging. We sought evaluate the risk of subsequent in subjects VF identified opportunistically computed tomography (CT) scans performed as part clinical practice. From radiology database Holbæk Hospital we first CT scan including thorax and/or abdomen 2000 consecutive men and women aged 50 years or older,...
Background: General practice systems in the Nordic countries share certain common features. The sector is based on model of a tax-financed supply services with political objective equal access for all. also challenges increased expectations to deliver primary prevention and workload as patients from hospital care are discharged earlier. However, within this framework, organized differently. This particularly relation private-public mix, remuneration use financial non-financial incentives....
In men and women with opportunistically identifiable vertebral fractures (VFs) on routine CT scans including the chest and/or abdomen, risk of death is 51% higher than in those no VF scan, 325% an age- sex-matched general population cohort. There little knowledge about patients VFs present radiological imaging. We evaluated aged 50 years or older not treated osteoporosis medications. Thoracic lumbar were identified through a blinded, two-step approach performed as part normal clinical care...
BackgroundIn the present study we analyze relationship between body mass index (BMI) and waist circumference (WC) future health care costs. On basis of relation these anthropometric measures mortality, hypothesized that for all levels BMI increased WC implies added costs (Hypothesis 1) given entails reduced 2). We furthermore assessed whether a combination two predicts better than either individual measure.Research Methodology/Principal FindingsData were obtained from Danish prospective...
The aim of this study was to compare the performance hospital care in four Nordic countries: Norway, Finland, Sweden and Denmark. Using national discharge registries cost data from hospitals, efficiency production somatic calculated for public hospitals. Data were collected using harmonized definitions inputs outputs 184 hospitals envelopment analysis used calculate Farrell estimates year 2002. Results suggest that there marked differences average between countries. In 2002, markedly higher...
Abstract Those responsible for monitoring and managing the performance of health‐care organisations face common problem that relationship between observed effort is difficult to establish. A solution compare multiple organisations, but this requires a sufficient number comparators. Faced with small sample, it may be possible exploit other information sources. Multilevel regression models are applied analyse six Danish vascular departments in 2004 using patient‐level data set. We find...
Abstract Background One in five patients with ischaemic heart disease (IHD) develop comorbid depression or anxiety. Depression is associated risk of non-adherence to cardiac rehabilitation (CR) and dropout, inadequate factor management, poor quality life (QoL), increased healthcare costs premature death. In 2020, IHD are expected be among the top contributors disease-burden worldwide. Hence, it paramount treat both underlying somatic as well eMindYourHeart will evaluate efficacy...
Abstract Background This analysis evaluated aqueous humour (AH) interleukin (IL)-6 concentrations and the association between AH IL-6 visual outcomes in patients with neovascular age-related macular degeneration (nAMD) or diabetic oedema (DMO) receiving anti–vascular endothelial growth factor (VEGF) monotherapy. Methods Post hoc of multicentre, double-masked, randomised HARBOR (NCT00891735) READ-3 (NCT01077401) trials. enrolled treatment-naïve nAMD patients. treatment-naïve/previously...
Many complicated postoperative vitreoretinal cases require reoperations. It is possible to perform some of these procedures outside the operating room. We describe examining room techniques for fluid-gas exchange, fluid and gas aspiration, adherent vitreous strand removal. also discuss a slit-lamp technique using sodium hyaluronate (Healon) following exchange eliminate optical distortion from endothelial striae.
Objectives: Surveillance programs are recommended to both families at high risk (Amsterdam-positive with known- and unknown mutation) moderate (families not fulfilling all Amsterdam criteria) of colorectal cancer (CRC). Cost-effectiveness has so far only been estimated for the group risk. The aim present study is determine cost-effectiveness surveillance where HNPCC participate. Methods: A decision analytic model (Markov model) developed assess offered from age 25 45, respectively. includes...