- Retinal Diseases and Treatments
- Ocular Infections and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Intraocular Surgery and Lenses
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Diabetes Management and Research
- Retinal and Macular Surgery
- Ophthalmology and Visual Impairment Studies
- Diabetes and associated disorders
- Ocular and Laser Science Research
- Diabetes Treatment and Management
- Retinal Development and Disorders
- Retinopathy of Prematurity Studies
- Corneal surgery and disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Visual perception and processing mechanisms
- Neonatal Respiratory Health Research
- Toxoplasma gondii Research Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Bacterial Identification and Susceptibility Testing
- Sinusitis and nasal conditions
- Ocular Surface and Contact Lens
- Dermatological and Skeletal Disorders
Tennessee Retina
1995-2024
University of Pittsburgh
1996-2021
Cleveland Clinic
2018
University of Washington
2017
University of Pittsburgh Medical Center
2009
Forbes Hospital
2004
Medical College of Wisconsin
1999
University of South Florida
1999
Tufts University
1999
Children's Hospital of Pittsburgh
1989
The contribution of diabetes duration, both pre- and postpuberty, to the development microvascular complications mortality in diabetic subjects was investigated three study populations from Children's Hospital Pittsburgh Insulin-Dependent Diabetes Mellitus (IDDM) Registry. Life-table analyses by total postpubertal IDDM duration were used evaluate differences prevalence diabetes-related diagnosed before during puberty, as defined an age at onset marker 11 yr for girls 12 boys. retinopathy...
Thirty-seven patients with criteria for systemic lupus erythematosus (SLE) and 18 normal controls were studied their spontaneous background IgM antibody plaque-forming clell number to specific chemical haptens. Active SLE had significantly more cells in peripheral blood a total of five determinants than did inactive disease or controls. This increased plaque forming-cells correlated depressed serum C3 levels by Spearman rank-order analysis. The finding elevated numberof defined haptens...
• Classic ocular toxoplasmosis initially involves inner retinal layers and is associated with marked vitreous reaction. We encountered three cases of punctate outer toxoplasmosis, a subset that characterized by multifocal gray-white lesions at the level deep retina pigment epithelium little or no overlying Acute may resolve to form fine granular white dots. Recognition this uncommon presentation important, since there some evidence treatment be effective.
Purpose: To compare the microbiologic yields and complication rates associated with vitreous needle tap biopsy in Endophthalmitis Vitrectomy Study (EVS). Methods: Of 420 EVS patients postoperative endophthalmitis, 201 received immediate or (without pars plana vitrectomy) by random assignment 193 completed 9-12 months of follow-up. Vitreous specimens were obtained a 20-gauge vitrectomy cutting instrument 22-27-gauge needle. If resistance to aspiration was noted, performed. Results: undergoing...
• One of two cases endogenous<i>Aspergillus</i>endophthalmitis in abusers intravenously administered drugs was treated successfully by subtotal pars plana vitrectomy; amphotericin B intravitreal, periocular, and systemic routes; flucytosine systemically.<i>Aspergillus</i>sp should be considered a possible pathogenic organism drug with endogenous endophthalmitis. An aggressive diagnostic therapeutic approach may result preservation useful vision.
The relationship between glycemic control and complications of insulin-dependent diabetes mellitus (IDDM) remains controversial. With the use glycosylated hemoglobin (HbA,) to assess from diagnosis onward, Pittsburgh Prospective Insulin-Dependent Diabetes Mellitus Cohort Study prospectively evaluated 80 new cases IDDM diagnosed at Children's Hospital Pittsburgh. This study presents findings in 62 patients 5 yr postdiagnosis. Only 7 patients, all girls, had any retinopathy (microaneurysms)....
<h3>Objective</h3>To compare baseline characteristics and treatment response of participants with hemiretinal vein occlusion (HRVO) those branch retinal (BRVO) or central (CRVO) in the Standard Care vs COrticosteroid for REtinal Vein Occlusion (SCORE) Study.<h3>Methods</h3>Eyes were randomized to standard care, 1 mg intravitreal triamcinolone acetonide, 4 acetonide. care was observation SCORE-CRVO trial grid photocoagulation SCORE-BRVO trial. The HRVO eyes enrolled Baseline characteristics,...
Abstract Background This analysis evaluated aqueous humour (AH) interleukin (IL)-6 concentrations and the association between AH IL-6 visual outcomes in patients with neovascular age-related macular degeneration (nAMD) or diabetic oedema (DMO) receiving anti–vascular endothelial growth factor (VEGF) monotherapy. Methods Post hoc of multicentre, double-masked, randomised HARBOR (NCT00891735) READ-3 (NCT01077401) trials. enrolled treatment-naïve nAMD patients. treatment-naïve/previously...
The retinal toxicity of intravitreally administered amphotericin B was compared in non-vitrectomised versus vitrectomised rabbit eyes. Doses 5 and 10 micrograms both groups resulted transient vitritis but had no effect on electroretinograms. Histopathological examination four weeks after injection showed vitreous cells minimal areas necrosis at or doses. At these doses vitrectomy did not modify the retinotoxic effects B. higher marked found groups.