A5081308923- Auditing, Earnings Management, Governance
- Corporate Finance and Governance
- Acute Lymphoblastic Leukemia research
- Accounting and Organizational Management
- Acute Myeloid Leukemia Research
- Risk Management in Financial Firms
- Asian Studies and History
- Financial Reporting and Valuation Research
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Erythrocyte Function and Pathophysiology
- Geotechnical Engineering and Soil Stabilization
- Corporate Social Responsibility Reporting
- Corporate Taxation and Avoidance
- Blood disorders and treatments
- Landfill Environmental Impact Studies
- Taxation and Compliance Studies
- Financial Markets and Investment Strategies
- Chronic Myeloid Leukemia Treatments
- Nonprofit Sector and Volunteering
- Viral-associated cancers and disorders
- Family Business Performance and Succession
- Hematopoietic Stem Cell Transplantation
- Blood groups and transfusion
- Public Policy and Administration Research
Deakin University
2011-2024
Royal Victoria Infirmary
2013-2024
Great North Children's Hospital
2012-2023
Newcastle upon Tyne Hospitals NHS Foundation Trust
2011-2022
Australian Regenerative Medicine Institute
2001-2011
Monash University
1996-2011
Accounting and Finance Association of Australia and New Zealand
2011
Australian National University
2011
Sunderland Royal Hospital
1997-2006
College of Accounting
2005
Rotation of audit partners is one the main policy initiatives that has been implemented in many jurisdictions around world to deal with concerns about quality. The basis any requirement limiting tenure there a reduction quality associated long periods tenure. Using data from Australia, where partner can be identified and for period rotation was not mandatory, we examine association between three measures examined are auditor's propensity issue going-concern opinion distressed companies,...
The genetic analysis of human primary immunodeficiencies has defined the contribution specific cell populations and molecular pathways in host defense against infection. Disseminated infection caused by bacille Calmette-Guérin (BCG) vaccines is an early manifestation immunodeficiencies, such as severe combined immunodeficiency. In many affected persons, cause disseminated BCG disease unexplained.We evaluated infant presenting with features immunodeficiency, including early-onset disease, who...
This study investigates voluntary demand for auditing by family businesses, a significant but relatively unexplored segment of the economy. The paper considers both internal and external using survey data to investigate impact firm characteristics linked cost vs. benefit engaging an auditor. Variables examined are size, debt, two agency proxies that measure separation ownership control, namely, proportion nonfamily management in firm, representation on board directors. also association...
Summary We retrospectively analysed the outcome of consecutive children with idiopathic severe aplastic anaemia in United Kingdom who received immunosuppressive therapy ( IST ) or matched unrelated donor MUD haematopoietic stem cell transplantation HSCT ). The 6‐month cumulative response rate following rabbit antithymocyte globulin ATG )/ciclosporin was 32·5% (95% CI 19·3–46·6) n = 43). 5‐year estimated failure‐free survival FFS 13·3% confidence interval [ ] 4·0–27·8). In contrast, 44...
The fusion gene MLL/AF4 defines a high-risk subtype of pro-B acute lymphoblastic leukemia. Relapse can be associated with lineage switch from to myeloid leukemia, resulting in poor clinical outcomes caused by resistance chemotherapies and immunotherapies. In this study, the relapses shared oncogene breakpoints their matched lymphoid presentations originated various differentiation stages immature progenitors through committed B-cell precursors. Lineage switching is linked substantial changes...
The present study investigates the determinants of internal audit outsourcing using survey data on 99 companies listed Australian Stock Exchange, where 54.5 per cent fully rely in-house facilities and 45.5 outsource some or all their function. Results from logistic regression analyses suggest that is associated with perceived cost savings technical competence external provider. For a subsample firms have previously undertaken activities before outsourcing, contrary to expectations, larger...
Accurate diagnosis of rare inherited anaemias is challenging, requiring a series complex and expensive laboratory tests. Targeted next-generation-sequencing (NGS) has been used to investigate these disorders, but the selection genes on individual panels narrow validation strategies have fallen short standards required for clinical use. Clinical-grade negative results requires test distinguish between lack adequate sequencing reads at locations known mutations real absence mutations. To...
The primary objective of this study was to determine the complete remission (CR) rate achieved with FLAG (fludarabine phosphate, cytarabine and granulocyte colony‐stimulating factor) regimen in patients relapsed or refractory acute myeloid leukaemia (AML) de novo anaemia excess blasts transformation (RAEB‐t). Secondary objectives were evaluate survival toxicity. Induction treatment consisted between one two courses FLAG. Patients achieving CR received consolidation treatment. Eighty‐three 89...
This article examines the potential costs to Australian auditors and their clients from issuance of first‐time going‐concern‐modified audit opinions. We examine population companies receiving a opinion during period 1994–97 matched sample financially distressed firms clean opinion. Results indicate that auditor switching is positively associated with receipt However, we find no empirical evidence there self‐fulfilling prophecy increased probability company failure following for in our study....
Purpose – This study aims to investigate whether “small- and medium-sized enterprises” (SMEs) benefit from their external accountants’ business advice through enhanced firm performance. Most SMEs draw on support, main advisors are accountants (Bennett Robson, 1999). The resource-based view of the suggests that firms will seek support if they perceive a gap in internal resources. Design/methodology/approach Data were collected questionnaire mailed random sample Australian SMEs, defined as...
Purpose The purpose of this paper is to test a conceptual framework explaining the role relationships and trust in enabling purchase business advice by small owner–managers from their external accountants. Design/methodology/approach study uses semi-structured interview approach with 20 small- medium-sized enterprise (SME) owners accountants London Melbourne. Findings data support framework’s central proposition that trust, rather than being antecedents demand for advice, are necessary...
We examine whether a firm's voluntary purchase of sustainability assurance is associated with reduced capital constraint and lower cost debt. also explore the effect provider (accountant/non‐accountant) country's level investor protection/creditor rights, on this association. Using panel dataset drawn from an international sample, we find that negatively both The associations are stronger for accounting firm providers than non‐accounting assurers. Further, firms operating in low protection...
This study investigates demand for auditing by family businesses, which is a significant but relatively unexplored segment of the economy. First, measures impact firm characteristics commonly linked to cost versus benefit engaging an auditor (proxies separation ownership and control, size debt). The nature business governance structures allows development more direct agency costs than traditional proxy management share (i.e., proportion non-family directors). Second, voluntary internal...
Journal Article Randomized Phase I Chemoprevention Dose-Seeking Study of α-Difluoromethylornithine Get access Richard R. Love, Love 1University Wisconsin Comprehensive Cancer CenterMadison, Wis * Correspondence to: M.D., University Center, Madison, WI 53792. Search for other works by this author on: Oxford Academic PubMed Google Scholar Paul P. Carbone, Carbone Ajit K. Verma, Verma Debra Gilmore, Gilmore Patrick Carey, Carey Kendra D. Tutsch, Tutsch Marcia Pomplun, Pomplun George Wilding...
Purpose – Business advisory services are an emerging service category for external accountants in the small and medium-sized enterprise (SME) environment. The purpose of this study is to investigate determinants SME demand business advice, drawing on agency theory, relational marketing resource-based literatures. Design/methodology/approach empirically tested theoretical predictions based Australia-wide survey SMEs, which 485 firms responded a questionnaire. Findings results show that...
SUMMARY The purpose of this study is to investigate the relative influence industry- and task-based experience on auditor performance. Prior research has shown that both forms can be beneficial, but studies thus far have not clarified their importance. Non-specialist participants are used as they gain task across a range industries, making it possible disentangle impact each literature indicates knowledge gained from industry-based applied unfamiliar tasks set within familiar industry...
Purpose – The purpose of this paper is to investigate the association between corporate governance mechanisms and quality forward-looking information in Chinese stock market which presents a mandatory disclosure environment for information. Design/methodology/approach Using sales forecasts proxy using precision accuracy measure disclosure, authors impact attributes on made by listed firms their 2010 annual reports, logistics ordinary least squares regressions. Findings find good has positive...
Geomembranes used in separation liners between old and new waste vertical expansions of landfills may be subject to strain caused by differential settlement. Therefore, it is important define a maximum allowable (MAS) that any given geomembrane can tolerate without compromising its required service life. In number instances some very low values have been proposed; as 0.25% 1.0% for high density polyethylene (HDPE). Such numbers are likely based on German regulations HDPE landfill require...
Abstract An important change in auditors’ reporting behaviour the period after high‐profile corporate collapses 2001 is that auditors were more likely to issue going‐concern (GC)‐modified audit opinions. Comparing company failure rates subsequent receiving a first‐time (FTGC)‐modified opinion pre‐ and post‐2001 periods, we find consistent type 1 error (misclassification) rate (the of survival among companies issued an FTGC opinion). Results are indicative maintaining GC accuracy when...
Summary Burkitt lymphoma is the most common malignancy in children Malawi, world's poorest country, where there a long history of treating this disease using 28‐day cyclophosphamide‐based protocol. Stage III / IV has had poor outcomes. In an attempt to improve outcome for higher stage disease, anthracyclines were added existing The disease‐free ( DFS ) and overall survival OS 58 with cytologically confirmed admitted during 2012–2014 treated protocol calculated. Six (10%) I ten (17%) II 42 or...
Malawi is one of the world's poorest countries, but despite this, has a dedicated paediatric oncology service. The service been hampered by inability to make timely cytological diagnosis in majority patients. A telemedicine programme was commenced help overcome this problem, and results for first 197 consecutive patients are described. compared with local reports where available. Most samples were fine needle aspirates (104/197-53%), others included bone marrow aspirates, peripheral blood...