A5101820918- Dialysis and Renal Disease Management
- Acute Kidney Injury Research
- Animal Virus Infections Studies
- Endoplasmic Reticulum Stress and Disease
- Bacterial Identification and Susceptibility Testing
- Neonatal Health and Biochemistry
- Lysosomal Storage Disorders Research
- Nutrition and Health in Aging
- Erythropoietin and Anemia Treatment
- Microbial Natural Products and Biosynthesis
- Electrospun Nanofibers in Biomedical Applications
- Viral gastroenteritis research and epidemiology
- Adipose Tissue and Metabolism
- Sepsis Diagnosis and Treatment
- Wound Healing and Treatments
- Sulfur Compounds in Biology
- Heme Oxygenase-1 and Carbon Monoxide
- Carbohydrate Chemistry and Synthesis
- Tissue Engineering and Regenerative Medicine
- Iron Metabolism and Disorders
- Cellular transport and secretion
- Phytochemical compounds biological activities
- Neonatal and Maternal Infections
- Adipokines, Inflammation, and Metabolic Diseases
- Nanoparticle-Based Drug Delivery
University Medical Center Groningen
2025
University of Groningen
2025
Zhejiang University
2023
Zhejiang University of Technology
2023
China Medical University
2023
Wenzhou University
2023
Northeastern University
2023
Utrecht University
2022-2023
Pharmo Institute
2022
The University of Texas Southwestern Medical Center
1996
Wound healing is an urgent clinical challenge, particularly in the case of chronic wounds. Traditional approaches to wound have limited therapeutic efficacy due lengthy times, risk immune rejection, and susceptibility infection. Recently, adipose-derived mesenchymal stem cell-derived exosomes (ADSC-exos) emerged as a promising modality for tissue regeneration repair. In this study, development novel extracellular matrix hydrogel@exosomes (ECM@exo) reported, which entails incorporation...
Palmitoyl-protein thioesterase is a lysosomal long-chain fatty acyl hydrolase that removes groups from modified cysteine residues in proteins. Mutations palmitoyl-protein were recently found to cause the neurodegenerative disorder infantile neuronal ceroid lipofuscinosis, disease characterized by accumulation of amorphous granular deposits cortical neurons, leading blindness, seizures, and brain death age three. In current study, we demonstrate [35S]cysteine-labeled lipid thioesters...
Chronic obstructive pulmonary disease (COPD), often caused by smoking, is a chronic lung with systemic manifestations including metabolic comorbidities. This study investigates adaptive and pathological alterations in adipose skeletal muscle tissue following cigarette smoke exposure using vivo vitro models. Mice were exposed to or air for 72 days the pre-adipose cell line 3T3-L1 was utilized as an model. Cigarette decreased body weight, proportional loss fat mass more pronounced than lean...
Proximal tubular damage is an important prognostic determinant in various chronic kidney diseases (CKDs). Currently available diagnostic methods do not allow for early disease detection and are neither efficient. Indoxyl sulfate (IS) endogenous metabolite protein-bound uremic toxin that eliminated via renal secretion, but accumulates plasma during dysfunction. Therefore, it may be suitable as a function marker. To evaluate this, fast bioanalytical method was developed validated IS species...
Swine acute diarrhoea syndrome coronavirus (SADS-CoV), which is a recently discovered enteric coronavirus, the major aetiological agent that causes severe clinical and intestinal pathological damage in pigs, it has caused significant economic losses to swine industry. Nonstructural protein 5, also called 3C-like protease, cleaves viral polypeptides host immune-related molecules facilitate replication immune evasion. Here, we demonstrated SADS-CoV nsp5 significantly inhibits Sendai virus...
Bilirubin is a key biomarker in the diagnosis of jaundice. Herein, we proposed simple and convenient quantitative method for fluorescent detection bilirubin. We developed copper nanoclusters coated by zinc-based metal-organic frameworks (Cu NCs@MOF). The prepared Cu NCs@MOF exhibited bright blue fluorescence excited with ultra-violet light well stability at various environments. More importantly, was used bilirubin based on emerging red emission peak induced Furthermore, were made into test...