A5003636442- Animal Nutrition and Physiology
- Seaweed-derived Bioactive Compounds
- Ruminant Nutrition and Digestive Physiology
- Gut microbiota and health
- Polysaccharides and Plant Cell Walls
- Genetic and phenotypic traits in livestock
- Polysaccharides Composition and Applications
- Microbial Metabolites in Food Biotechnology
- Phytase and its Applications
- Gastric Cancer Management and Outcomes
- Agroforestry and silvopastoral systems
- Protein Hydrolysis and Bioactive Peptides
- Agronomic Practices and Intercropping Systems
- Antimicrobial Peptides and Activities
- Epigenetics and DNA Methylation
- Phytochemicals and Antioxidant Activities
- Ginger and Zingiberaceae research
- Metastasis and carcinoma case studies
- Viral Infectious Diseases and Gene Expression in Insects
- NF-κB Signaling Pathways
- Effects of Environmental Stressors on Livestock
- Cancer-related gene regulation
- Cancer-related molecular mechanisms research
- Plant tissue culture and regeneration
- Moringa oleifera research and applications
Shandong Agricultural University
2014-2024
Shandong University
2024
Ministry of Agriculture and Rural Affairs
2023
Jeju National University
2023
Shandong Center for Disease Control and Prevention
2021
Taian City Central Hospital
2021
University of California, Davis
2019-2021
Kerala Veterinary and Animal Sciences University
2020
Municipality of Tai'an
2020
Peking University
1988-2015
Intercropping legume with cereal is an extensively applied planting pattern in crop cultivation. However, forage potential and the degradability of harvested mixtures from intercropping system remain unclear. To investigate feasibility applying as a supply source to ruminants, two consecutive experiments (experiments 1 2) involving field cultivation trial subsequent vivo degradable experiment were conducted determine production performance ruminally characteristics mixture alfalfa/corn-rye...
The polysaccharide isolated from alfalfa was considered to be a kind of macromolecule with some biological activities; however, its molecular structure and effects on immune cells are still unclear. objectives this study were explore the extraction purifying methods (Medicago sativa L.) (APS) decipher composition characteristics, as well activation lymphocytes. crude polysaccharides by water alcohol precipitation purified semipermeable membrane dialysis. Five batches samples obtained five...
In the normal physiological state, intestinal epithelial cells act as a defensive frontline of host mucosal immunity to tolerate constant exposure external stimuli. this study, we investigated potential anti-inflammatory and gut permeability protective effects
Feeding pelleted total mixed rations (TMR) instead of traditional loose concentrate plus forage to fattening lambs is an emerging practice. This study aimed determine the effects feeding TMR on feed intake behaviour, growth performance, digestion, rumen fermentation characteristics, microbial community, serum parameters, slaughter meat quality, and economic outcome. Two physical forms (pelleted vs. un-pelleted) composed same ingredients with particle sizes were compared in three animal...
Xing X‐F, Li H, Zhong X‐Y, Zhang L‐H, Wang X‐H, Liu Y‐Q, Jia S‐Q, Shi T, Niu Z‐J, Peng Y, Du G‐G, Hu Lu A‐P, J‐Y, Chen S & Ji J‐F (2011) Histopathology 59 , 198–206 Phospholipase A2 group IIA expression correlates with prolonged survival in gastric cancer Aims: The secreted phospholipase type (PLA2G2A) gene has been identified as a modifier of intestinal adenoma multiplicity Apc Min/+ mice. aim the present study was to analyse clinical significance PLA2G2A human cancer. Methods and...
Abstract Alfalfa polysaccharide (APS) is a bioactive component extracted from alfalfa that exhibits potent antioxidant properties. However, the cellular and molecular mechanisms underlying these properties remain unclear. To explore mechanism by which APS exerts effects, an H 2 O -induced oxidative stress mouse embryonic fibroblast (MEF) model was established. Cell proliferation, enzyme activity, immune cytokine expression, related protein expression were examined in APS-supplemented or...
Little attention has been paid to root distribution in combined perennial legume and annual cereal crops. The main objectives of this study were explore the regularity influence on nitrogen (N) acquisition different alfalfa (Medicago sativa L.) corn (Zea mays intercropping patterns. A three year (2007–2009) field experiment studied four patterns alternating rows with alfalfa:corn sown at 2:2, 3:2, 4:2, 5:2. Sole crops used as controls. Roots sampled over 3 consecutive years by auger sampling...
High fat diet-induced obesity and lipopolysaccharide-induced inflammation/inhibition of the browning adipocytes were reversed by <italic>p</italic>-coumaric acid-enriched peanut sprouts.
Polysaccharides derived from Laminaria japonica (LJPS) have shown a variety of beneficial effects on improving human health; however, the structural features and bioactivities long-chain LJPS remain unclear. This study aimed to investigate characteristics novel LJPS. Results showed that was composed Fuc, Rha, Ara, Gal, Glc, Xyl, Man, Fru, Rib, GalA, GluA, GlcA, ManA, with molar ratio 35.71:1.48:0.28:13.16:0.55:2.97:6.92:0.58:0.41:0.14:3.16:15.84:18.79. Of these, ManA were predominant...
The pelleted total mixed ration (PTMR) has a positive effect on the productivity of fattening lambs. However, whether beneficial effects are underpinned by altering rumen microbiota and metabolome that remain unclear. This study aimed to investigate correlations among growth performance, ruminal microbiota, lambs fed PTMR diet. A 100 crossbred (Dorper sheep × Fine-wool sheep) ram at 55 days age with similar body weight (BW) (13.2 ± 0.5 kg) were randomly allocated 10 pens either (PTMR group)...
Alfalfa polysaccharide (APS) activates the immune functions of splenic B cells by TLR4, acting through MAPK and NF-κB signaling pathways, potently p38 pathway.
Seaweed is known to have various health-promoting effects. However, the mechanisms underlying seaweed’s antidiabetic effects remain unclear. We investigated potential of seaweed water extracts and further examined their mechanism(s) using C2C12 mouse skeletal muscle cells. Briefly, we screened physiochemical properties seven by comparing antioxidant α-glucosidase inhibitory Among them, three extracts, Undaria pinnatifida sporophyll (UPS), Codium fragile (CF), Gracilaria verrucosa (GV), were...
This study investigated the beneficial effects of a Laminaria japonica polysaccharide (LJPS) on systemic health ducks by modulating gut microbiome and metabolome. Our findings demonstrated that LJPS supplementation enhanced overall growth performance physiological immune antioxidant index ducks. In addition, LJPS-fed group significantly increased abundances intestinal Bacteroides Prevotellaceae with decreased α-diversity than in control group. Among total 1840 metabolites, 186 metabolites...
Abstract Salmonella serotype (ser.) Enteritidis infection in broilers is a main foodborne illness that substantially threatens food security. This study aimed to examine the effects of novel polysaccharide isolated from alfalfa (APS) on intestinal microbiome and systemic health S. ser. Enteritidis- infected broilers. The results indicated receiving APS-supplemented diet had improved ( P < 0.05) growth performance gut than those fed no diet. Supplementation with APS enhanced richness...
Zearalenone (ZEA), an estrogenic mycotoxin, is produced mainly by Fusarium fungi. Previous studies have indicated that acute ZEA exposure induced various damages in different species; however, its transparent hematotoxicity female piglets at dietary levels of 1.1 to 3.2 mg/kg has not been shown. The present study was conducted investigate the effects (1.1-3.2 mg/kg) on hematology, T lymphocyte subset, immunoglobulin, antibody titer, proliferation rate (LPR), and interleukin-2 (IL-2)...
Considerable evidence suggests that dietary energy levels and gut microbiota are pivotal for animal health productivity. However, little information exists about the correlations among level, performance, metabolome of donkeys. The objective this study was to investigate mechanisms by which content dictates growth performance modulating intestinal microbiome Thirty-six nine-month-old male Dezhou donkeys with similar body weights were randomly assigned two groups fed low- or high-energy diets...
The IC53 gene was reported to be upregulated In the colon adenocarcinoma cell line SW480. Here, we show that expression level of is positively correlated with grade and depth invasion in colon. Injection stably transfected HCT-116 cells into athymic nude mice promoted tumor growth. Furthermore, overexpression increased invasive growth, which could dramatically prevented by knocking down siRNA. effects on cell-invasive growth were mediated upregulation integrins, activation...
Polysaccharides from alfalfa (Medicago sativa L.) (APS) exhibit a variety of bioactivities; however, little information is available on the effects ecological environment structural characteristics and bioactivities APS. This study aimed to investigate two APS types isolated alfalfa; these APSs were obtained cultured in normal soil (APS1) or saline-alkali (APS2). Results indicated that kinds had same monomer compositions different molar proportions, where APS2 greater content arabinose...
Objective: The effects of adding fermented feed to a pelleted total mixed ration (PTMR) on the growth performance lambs remain unclear. present study aimed investigate efficiency and productivity that were fed PTMR containing soybean meal (FSM) or wheat bran (FWB).Methods: Sixty 90-d-old hybrid randomly allocated into 12 pens (5 lambs/pen) assigned 4 dietary treatments (3 pens/treatment) with (basal diet), 2% FSM, <i>Lactobacillus</i>- yeast-FWB (L-FWB Y-FWB) addition in basal...