- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Respiratory Support and Mechanisms
- Sleep and Wakefulness Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neonatal Respiratory Health Research
- Cystic Fibrosis Research Advances
- Sleep and related disorders
- Tracheal and airway disorders
- Foreign Body Medical Cases
- Restless Legs Syndrome Research
- Non-Invasive Vital Sign Monitoring
- Nitric Oxide and Endothelin Effects
- Cardiovascular and Diving-Related Complications
- Restraint-Related Deaths
- Amyotrophic Lateral Sclerosis Research
- Child Nutrition and Feeding Issues
- Medical Research and Treatments
- Airway Management and Intubation Techniques
- Palliative Care and End-of-Life Issues
- Heart Rate Variability and Autonomic Control
- Cardiovascular Health and Disease Prevention
- Parkinson's Disease Mechanisms and Treatments
- Healthcare Decision-Making and Restraints
Liverpool Hospital
2007-2024
Ingham Institute
2017-2024
South Western Sydney Local Health District
2017-2024
UNSW Sydney
2017-2024
Woolcock Institute of Medical Research
2008
Royal Prince Alfred Hospital
2004
Abstract The Epworth Sleepiness Scale is used frequently to measure excessive daytime sleepiness in research and clinical settings, although there limited evidence on test–retest reliability, particularly among sleep clinic populations. objective of this study was evaluate the reliability instrument adult patients recruited from a public hospital Sydney, Australia. English‐speaking participants self‐completed two occasions, at specialist visit night diagnostic polysomnography. Of 108...
Abstract Purpose Polysomnography (PSG) may be completed in the home environment (unattended), and when self-applied, allow collection of data with minimal healthcare worker intervention. Self-applied, unattended PSG using Somte V2 (Somte) has not been validated pregnant women early to mid-gestation. We undertook a study evaluate accuracy compared attended PSG. The agreement between apnoea hypopnea index (AHI) respiratory disturbance (RDI) scores mid-gestation were assessed. Methods Pregnant...
Abstract Background and Objective Hypercapnic respiratory failure (HRF) can occur due to severe disease but also because of multiple coexistent causes. There are few data on the prevalence antecedent causes for HRF effect these prognosis, especially where study inclusion has not been biased with respect primary diagnosis, interventions received or clinical outcome. We sought determine pre‐specified conditions among patients in‐hospital mortality. Methods Cross‐sectional from 2013 2017....
Objective We sought to describe the long-term prognosis for a population-based cohort of people with hypercapnic respiratory failure (HRF) and associations between underlying diagnoses risks death rehospitalisation. Methods performed historical study all persons HRF in Liverpool local government area New South Wales, Australia, 3-year period from 2013 2015. Cohort members were identified using arterial blood gas results Hospital demonstrating pH ≤7.45 PaCO 2 >45 mm Hg within 24 hours...
Abstract Purpose There is a paucity of data on preferences for obstructive sleep apnoea (OSA) diagnostic tests during pregnancy. Simple test completion rates fail to capture patient preference or experience completing tests. We assessed preference, ease use, convenience, and the repeatability level I, II III tests, using questionnaires, in pregnant women early mid-gestation. Methods Pregnant with signs symptoms OSA, at high risk cardiometabolic disorders pregnancy completed studies by 24...
Abstract Background Evidence‐based screening tools are required for detection of daytime hypercapnia in high‐risk patient populations. Aims To determine the validity supine awake oximetry as a test and severe sleep disordered breathing ( SDB ) super‐obese patients. Methods This was cross‐sectional diagnostic evaluation adults (body mass index >50 kg/m 2 presenting to Liverpool Hospital, Australia, between 2009 2015 polysomnography PSG arterial blood gas measurement. Supine oxygen...
Abstract Objective There are no population-based data on the relative importance of specific causes hypercapnic respiratory failure (HRF). We sought to quantify associations between hospitalisation with HRF and potential antecedent including chronic obstructive pulmonary disease (COPD), sleep apnea, congestive cardiac failure. used prevalence these conditions estimate population attributable fraction for each cause. Methods A case–control study was conducted among residents aged ≥ 40 years...
Unrecognised obstructive sleep apnoea (OSA) has been associated with adverse cardiorespiratory perioperative outcomes. However, changing anaesthetic and management, there is ongoing uncertainty about the importance of OSA as a risk factor for post-operative complications.
Abstract General practitioner training on obstructive sleep apnoea and long-term care: a pilot study Introduction Obstructive (OSA) can be treated using continuous positive airway pressure (CPAP) therapy; however, many patients experience difficulties acclimatising persisting with this treatment. In view of the increasing prevalence OSA, evidence-based models care not limited to physicians are urgently required. A was conducted feasibility implementing an education session for general...
Abstract Foreign body inhalation (FBI) is an uncommon clinical entity in adults. Despite this, FBI under‐recognized, serious, and easily treatable condition. The authors report a case of 31‐year‐old female asthmatic who presented with wheeze cough not responding to therapy. Chest computed tomography bronchoscopy confirmed foreign distal the left upper lobe vestibule. non‐organic material was removed rigid cryoprobe resolution symptoms. remains important differential those presenting...
Motor neuron disease (MND) is a neurodegenerative disorder leading to functional decline and death. Multidisciplinary MND clinics provide an integrated approach management facilitate discussion on advanced care directives (ACDs). The study objectives are analyse (1) the prevalence of ACD in our clinic, (2) relationship between patient demographics (3) decision-making variables such as NIV, PEG, hospital admissions location death.Using clinic records, all patients who attended Liverpool...
Abstract Introduction The detection of obstructive sleep apnoea (OSA) in pregnant women early gestation using polysomnography (PSG) was logistically difficult during covid-19 lockdowns. Reliable alternates to PSG haven’t been well validated pregnancy. We compared the agreement between self-applied, unattended Somte and attended PSG, by 24 weeks gestation. Methods Women were recruited undergo Grael Tests scored a single experienced scorer (blinded result). An apnoea-hypopnea index (AHI) 5 or...
Abstract Introduction A range of test options are available to diagnose OSA. Test acceptability is measured via successful completion, though this fails capture the patient preference. There a paucity data on particularly in pregnancy. We thus developed questionnaires assess preference and Apnealink-Air, Somte Grael tests, pregnancy till 24 weeks gestation. Methods Eighty-four pregnant women by gestation were invited complete home unattended-self-applied-Somte-PSG attended-Grael-PSG....