- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Gastrointestinal motility and disorders
- Neuropeptides and Animal Physiology
- Coronary Interventions and Diagnostics
- Cardiovascular Health and Disease Prevention
- Diabetes Treatment and Management
- Gastroesophageal reflux and treatments
- Neuroendocrine regulation and behavior
- Venous Thromboembolism Diagnosis and Management
- Metabolism, Diabetes, and Cancer
- Cardiovascular and Diving-Related Complications
- Cardiac Structural Anomalies and Repair
- Enhanced Recovery After Surgery
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Arrhythmias and Treatments
- Hemodynamic Monitoring and Therapy
- Cardiac tumors and thrombi
- Cardiomyopathy and Myosin Studies
- Hedgehog Signaling Pathway Studies
- Aortic Thrombus and Embolism
- Anesthesia and Pain Management
- Antiplatelet Therapy and Cardiovascular Diseases
Karlstad Central Hospital
2006-2024
Karlstad University
1998-2002
Linköping University
1999
Linköping University Hospital
1998
University of Gothenburg
1991-1996
Objectives: In a long-term randomised coronary artery bypass grafting (CABG) study, the patency rate using new 'no touch' (NT) vein-graft preparation technique was superior to conventional (C) technique. This cineangiographic and intravascular ultrasound (IVUS) substudy examined possible mechanisms. Methods: A total of 45 patients (118 grafts) in NT group 46 (112 C had patent grafts at short-term follow-up after 18 months. Thirty-seven (91 37 (77 8.5 years, were evaluated on scale from 0...
<h3>OBJECTIVE</h3> To investigate the value of Simpson's rule, Teichholz's formula, and recording mitral ring motion in assessing left ventricular ejection fraction (EF) patients with hypertrophy. <h3>DESIGN</h3> Left calculated by rule Techholz's formula estimated was compared values obtained radionuclide angiography. <h3>SETTING</h3> Secondary referral centre. <h3>PATIENTS</h3> 16 hypertrophy a clinical diagnosis hypertrophic cardiomyopathy or hypertension. <h3>RESULTS</h3> Calculation...
Introduction Conventional vein grafts have a high risk of thrombosis and early atherosclerosis. Percutaneous coronary intervention (PCI) in conventional is associated with higher incidence late adverse cardiac events. The aim this study was to evaluate the long-term results after PCI saphenous (SVG) harvested no-touch technique compared technique. Methods This single-center, retrospective, cohort study, based on data from Swedeheart register. inclusion criterion individuals who underwent...
Left ventricular systolic and diastolic function can be assessed by studying mitral ring motion. Reference values for a wide range of age body size are lacking however. The motion the was studied with M-mode echocardiography using apical four- two-chamber views. Data reported as average measurements four points on ring. were analysed stepwise multiple regression technique, age, gender, height, weight, surface area heart rate independent variables. A total 70 healthy subjects studied. In...
The profuse fluid losses and morbidity of patients suffering from obstructive ileus are closely related to inflammatory changes in the obstructed bowel wall. Previous experimental studies have shown that use steroids NSAIDs can reduce ileus. In present study, we investigated effects lidocaine on since local anesthetics been possess wide potent anti-inflammatory properties. Hexamethonium atropine were used study importance autonomic nervous system obstruction.Experiments performed rats vivo....
We aimed to investigate the effect of liraglutide treatment on heart function in type 2 diabetes (T2D) patients with subclinical failure.Randomized open parallel-group trial. 62 T2D (45 male) failure were randomized either once daily 1.8 mg, or glimepiride 4 both add metformin 1 g twice a day. Mitral annular systolic (s') and early diastolic (e') velocities measured at rest during bicycle ergometer exercise, using tissue Doppler echocardiography. The primary endpoint was 18-week changes...
Background: Previous observations have shown vasoactive intestinal peptide (VIP) to be an important secretagogue in the gut, whereas somatostatin has been reported inhibit VIP release and fluid secretion. Methods: The possible role of as mediator inflammation losses obstructive ileus was investigated vivo a chronic rat model with thread ligation jejunum. Extravasated Evans blue (Eb)-stained albumin quantified by spectrophotometry. Net secretion measured gravimetric technique. antiserum used...
Objectives. To investigate the long-term clinical outcome, averaging 8.5 years, of two saphenous vein harvesting techniques for CABG; no touch (NT) versus conventional (C). Design. In a randomized study, 49/52 in group NT and 44/52 were evaluated reangina, myocardial infarction, new revascularization, functional class, risk factors medical treatment. The grafts native coronary arteries correlated to occurrence reangina. Results. There significantly more patients free from angina NYHA class I...
Objectives To assess the left ventricular heart function and clinical outcome 16 years after coronary artery bypass surgery. Design In a randomised trial, no-touch (NT) vein graft in surgery has shown superior patency rate, slower progression of atherosclerosis better compared to conventional (C) at 8.5 years. All patients mean time were offered an echocardiographic examination. Results NT-group 34 C-group 31 underwent echocardiography A significantly ventricle ejection fraction was seen...
Quality Improvement in Coronary Care, a Swedish multicenter, controlled quality-improvement (QI) collaborative, has shown significant improvements adherence to national guidelines for acute myocardial infarction, as well improved clinical outcome. The objectives of this report were describe the sustainability after withdrawal study support and consolidation period 3 months whether disseminated treatments diagnostic procedures other than those primarily targeted.Multidisciplinary teams from...
The aim of the present in vivo study was to investigate anaesthetized rats, effects selective adrenergic agonists and antagonists on basal gastric tone phasic contractions by use a volumetric method. L‐phenylephrine, an alpha‐1 agonist, induced hypertension, bradycardia significant relaxation. Clonidine, alpha‐2 caused hypotension, contraction reduction amplitude contractions. Salbutamol, beta‐2 dose‐dependent tachycardia inhibition whereas prenalterol, beta‐1 without any influence tone....
Painful stimuli have been shown to inhibit gastric motility in animal experiments and delay emptying humans. The aim of the present study was investigate detail mechanisms involved pain‐induced inhibition. Pain stimulation by exerting pressure on a testicle induced prompt relaxation which lasted throughout period stimulation. Pain‐induced significantly reduced selective α ‐1 blocker, prazosin, non‐selective β ‐blocker, propranolol. Similarly inhibition tone bilateral cervical vagotomy. In...
We investigated the effects of adrenergic, cholinergic and vasoactive intestinal polypeptide (VIP)-ergic agonists antagonists on amplitude gastric phasic contractions in anaesthetized rat using a volumetric model. The was reduced significantly by atropine, hexamethonium or bilateral cervical vagotomy indicating that neural activity involving both muscarinic nicotinic receptors intact vagal nerve function are integral parts control basal motility. In contrast, neither selective alpha 1-, 2-...
Could a diastolic dysfunction and an increased LV-filling pressure according to ASE/EACVI guidelines be detected or ruled out by the E/a´ratio in patients with decreased ejection fraction.We retrospectively evaluated function of 113 unselected in-hospital patients, aged 40-84 years, sinus rhythm no mild valve disease, having systolic (EF ≤50%) using new compared these results derived from E wave mitral flow a´velocity tissue Doppler.The average E/a´ ratio is strong predictor grade II-III...
Objectives. To compare the ability of a´ velocity and e´ in predicting a dominant diastolic pulmonary vein flow (S/D ratio <1) patients with normal ejection fraction. Design. We retrospectively evaluated function according to ASE/EACVI guidelines, S/D septal, lateral average 293 unselected in-hospital patients, aged 39–86 years, sinus rhythm no or mild valve disease, having systolic (EF >50%). Results. There was good linear correlation between velocity, but tendency towards negative...
ABSTRACT Objectives To evaluate the long-term angiographic patency of saphenous vein grafts (SVG) harvested using no-touch technique compared to conventional technique. Methods This was a single-center, retrospective, cohort study. The inclusion criteria were individuals who underwent CABG (coronary artery bypass grafting) between January 1995 and July 2020, successively needed clinically-driven angiography. primary endpoint patency. secondary endpoints differences in based on sub-group...