A5025409829- Acne and Rosacea Treatments and Effects
- Dermatology and Skin Diseases
- Pharmacological Effects of Natural Compounds
- Skin Protection and Aging
- RNA and protein synthesis mechanisms
- Reconstructive Surgery and Microvascular Techniques
- Nail Diseases and Treatments
- Phytochemistry and Bioactive Compounds
- Cancer-related molecular mechanisms research
- Wound Healing and Treatments
- RNA modifications and cancer
- melanin and skin pigmentation
- Ferroptosis and cancer prognosis
- Veterinary medicine and infectious diseases
- Natural product bioactivities and synthesis
- Escherichia coli research studies
- Brucella: diagnosis, epidemiology, treatment
- Dermatological diseases and infestations
- Histiocytic Disorders and Treatments
- Tuberous Sclerosis Complex Research
- Advanced machining processes and optimization
- HER2/EGFR in Cancer Research
- Lipid metabolism and disorders
- Morinda citrifolia extract uses
- Burn Injury Management and Outcomes
First Affiliated Hospital of Kunming Medical University
2012-2025
Kunming Medical University
2012-2025
Fujian Medical University
2024
Institute of Animal Sciences
2023
Chinese Academy of Agricultural Sciences
2013-2023
Shandong University of Traditional Chinese Medicine
2022
Jilin University
2018-2022
Affiliated Hospital of Hangzhou Normal University
2011-2014
Lanzhou Veterinary Research Institute
2013
Xijing Hospital
2008
Dengue is the most common arthropod-borne viral (Arboviral) illness in humans. The genetic features concerning codon usage of dengue virus (DENV) were analyzed by relative synonymous usage, effective number codons and adaptation index. evolutionary distance between DENV natural hosts (Homo sapiens, Pan troglodytes, Aedes albopictus aegypti) was estimated a novel formula. Finally, preference for translation initiation region this also analyzed. result indicates that general trend 59 four...
Purpose To investigate the potential genetic basis of Netherton syndrome (NS) through first- and second-generation DNA sequencing techniques. Additionally, we evaluated therapeutic efficacy Abrocitinib in NS patients.
Propionibacterium acnes (P. acnes) has been implicated in the progression of acne inflammation. Because current medications have various side effects, it is necessary to explore alternative possessing anti-inflammatory activity against P. acnes. We investigated inhibitory effects polyphyllin I (PPI) on acnes-induced inflammation vitro. In this study, we examined PPI production inflammatory cytokines HaCaT keratinocytes treated with heat-killed These showed increased expression Toll-like...
Objective Antibiotics have been routinely used for several decades against Propionibacterium acnes ( P. ), but antibiotic resistance of is becoming a global problem. Only one related Chinese study available. The aim this was to assess the susceptibility obtained from patients with acne in Southwest China. Design This prospective cross-sectional study. Cutaneous samples were lesions on face 375 patients. Samples cultured anaerobic medium identify presence . Susceptibility tests isolated...
The process of intracellular proteolysis through ATP-dependent proteases is a biologically conserved phenomenon. stress responses and bacterial virulence various pathogenic bacteria are associated with the Clp protease. In this study, Brucella abortus 2308 strain, ΔclpP, was constructed to characterize function ClpP peptidase. growth ΔclpP mutant strain significantly impaired in TSB medium. results showed that sensitive acidic pH stress, oxidative high temperature, detergents, osmotic...
The pathogen of a new type disease – fatal bacterial granuloma after trauma (FBGT) was found to be Propionibacterium acnes (P. acnes). Although in vitro studies showed that the pathogenic P. are sensitive conventional antibiotics, treatments FBGT patients with these antibiotics were ineffective. underlying mechanisms not clear. Since able form biofilm on orthopaedic biomaterials vitro, and vulgaris known vivo, we hypothesize pathogens also during pathogenesis, which may 1 reasons for...
Background The vonoprazan (VPZ)-amoxicillin (AMO) dual therapy (VA) demonstrates a satisfactory eradication rate for Helicobacter pylori (H. ). However, the optimal dosage of AMO in this regimen remains uncertain. objective study is to investigate efficacy different doses VA first-line treatment H. infection. Methods A total 192 treatment-naive -infected patients were randomly assigned one three groups: low-dose (LD-VA: VPZ 20 mg b.i.d + 750 t.i.d), moderate-dose (MD-VA:VPZ 1000 and...
Hair loss, including alopecia, is a common and distressing problem for men women, as result, there considerable interest in developing treatments that can prevent or reverse hair loss. Dermal papillae closely interact with epidermal cells play key role during follicle induction morphogenesis. As dermal papilla (DPCs) lose their hair‑inducing ability monolayer cultures <em>in vitro</em>, it difficult to obtain <em>de novo</em> structures following DPC transplantation vivo</em>. The present...
More than 40% of lung cancers are adenocarcinoma (LUAD) worldwide. However, the prognosis LUAD is poor for lack effective treatment methods. Our study identified PLK1 as a novel biomarker and target LUAD. Based on Cancer Genome Atlas (TCGA) database, differentially expressed genes (DEGs) from 551 cases were analyzed Kyoto Encyclopedia Genes Genomes (KEGG) enrichment analysis. To explore biological pathways tumor-infiltrating immune cells (TICs) using gene set variation analysis (GSVA)...
Bone marrow mesenchymal stem cell (BMSC) transplantation is effective for repairing spinal cord injuries (SCIs); however, there are limitations of clinical BMSC applications. Previously, we reported that dermal papilla cells (DPCs) secrete brain-derived neurotrophic factor and glial line-derived more actively than BMSCs. To analyze the therapeutic function DPCs in SCI, primary BMSCs were cultured from same green fluorescence protein-transgenic rat. The suspended rat-tail collagen I...
This study aims to investigate the effect of Epstein-Barr virus (EBV) reactivation or EBV with dexamethasone (DXM) in patients adverse drug reactions (ADRs) through evaluating levels monocyte, macrophage M2/M1, and cytokines, investigating whether expression receptor EphA2 could specifically influence activation ADRs. We performed a prospective longitudinal analyze monocytes, macrophages, M2/M1 ratio, including interleukin (IL)-4, IL-13, tumor necrosis factor (TNF)-α, interferon (IFN)-γ,...
Abstract More than 40% of lung cancers are adenocarcinoma (LUAD) worldwide. However, the prognosis LUAD is poor for lack effective treatment methods. Our study identified PLK1 as a novel biomarker and target LUAD. Based on Cancer Genome Atlas (TCGA) database, differentially expressed genes (DEGs) from 551 cases were analyzed Kyoto Encyclopedia Genes Genomes (KEGG) enrichment analysis. To explore biological pathways tumor-infiltrating immune cells (TICs) using gene set variation analysis...