A5003040628- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Liver Disease Diagnosis and Treatment
- Phagocytosis and Immune Regulation
- Pharmacological Effects of Natural Compounds
- Liver physiology and pathology
- Gastroesophageal reflux and treatments
- Music Therapy and Health
- Fibroblast Growth Factor Research
- Amoebic Infections and Treatments
- Histiocytic Disorders and Treatments
- IgG4-Related and Inflammatory Diseases
- Kidney Stones and Urolithiasis Treatments
- Veterinary medicine and infectious diseases
- COVID-19 Clinical Research Studies
- Body Contouring and Surgery
- Gastrointestinal Tumor Research and Treatment
- Eosinophilic Disorders and Syndromes
- Tuberous Sclerosis Complex Research
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
Zhejiang University
2024
Fujian Medical University
2020-2024
Fujian University of Traditional Chinese Medicine
2023-2024
Xiamen University
2020-2024
Sir Run Run Shaw Hospital
2024
117th Hospital of People's Liberation Army
2020-2023
Second Military Medical University
2017-2022
Changhai Hospital
2017-2022
Weatherford College
2022
Fudan University
2021
Background Chronic pancreatitis (CP) is a chronic inflammatory disease of the pancreas. This study aimed to compare natural course alcoholic (ACP) and idiopathic (ICP). Methods CP patients admitted our center from January 2000 December 2013 were enrolled. Characteristics compared between ACP ICP patients. Cumulative rates diabetes mellitus (DM), steatorrhea, pancreatic stone, pseudocyst, biliary stricture, cancer after onset diagnosis calculated, respectively. The cumulative DM steatorrhea...
<b>Background and aims</b> Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) is recommended as the first-line treatment for pancreatic stones. However, how well P-ESWL performs in pediatric patients remains unclear. We aimed to evaluate safety efficacy of with chronic pancreatitis. <b>Methods </b>This prospective observational study was conducted painful pancreatitis who underwent P-ESWL. Patients aged under 18 years were included group; over same period assigned control group. For...
Abstract Chronic pancreatitis (CP) is characterized by persistent inflammation of the pancreas that results in progressive loss endocrine and exocrine compartment owing to atrophy and/or replacement with fibrotic tissue. Currently, clinical therapeutic scheme CP mainly symptomatic treatment including pancreatic enzyme replacement, glycaemic control nutritional support therapy, lacking specific drugs for prevention suppression fibrosis aggravating CP. Here, we investigated effect...
Abstract Background and Aim Pancreatic pseudocyst is a common complication of chronic pancreatitis. The identification risk factors development nomogram for pancreatic pseudocysts in pancreatitis patients may contribute to the early diagnosis intervention pseudocysts. Methods Patients with admitted our center from January 2000 December 2013 were enrolled. Cumulative rates after onset calculated. randomly assigned, 2:1 ratio, training validation cohort. Based on cohort, identified through Cox...
To identify the risk factors and develop nomograms for common bile duct (CBD) stricture in chronic pancreatitis (CP) patients.CBD is a complication CP has variable clinical presentation ranging from asymptomatic to overt jaundice cholangitis.Patients with admitted Changhai Hospital (Shanghai, China) January 2000 December 2013 were enrolled. Cumulative rates of CBD after onset diagnosis calculated. Patients randomly assigned, 2:1 ratio, training validation cohort. On basis cohort, symptomatic...
Abstract Background and Aim Diabetes mellitus (DM) is a common complication of idiopathic chronic pancreatitis (ICP), which impairs the quality life for patients. This study aimed to identify risk factors develop nomogram DM in ICP help early diagnosis. Methods Idiopathic patients admitted our center from January 2000 December 2013 were included. Cumulative rates calculated by Kaplan–Meier method. Patients randomly assigned, 2:1 ratio, training validation cohort. Based on cohort, identified...
Abstract Background and Aim Pancreatic extracorporeal shock wave lithotripsy (P‐ESWL) is a first‐line treatment for chronic pancreatitis (CP) patients with pancreatic stones. However, the performance of P‐EWSL in geriatric remains unclear. We aimed to evaluate safety efficacy P‐ESWL them. Methods This prospective study was conducted painful CP who underwent P‐ESWL. Patients aged over 65 years were included group; under assigned control group. For long‐term follow‐up investigation, matched...
Pancreatic fibrosis is one of the most important pathological features chronic pancreatitis (CP), and pancreatic stellate cells (PSCs) are considered to be key cells. Puerarin flavonoid active component in Chinese herb Radix Puerariae , it exhibited anti-fibrotic effect various fibrous diseases recently. However, impact molecular mechanism puerarin on CP remain unknown. This study systematically investigated vivo vitro . H&amp;E staining, Sirius Red qRT-PCR Western blotting analysis...
The objective of this study was to evaluate the safety and efficacy pancreatic extracorporeal shock wave lithotripsy (P-ESWL) in chronic pancreatitis (CP) patients with stones after previous surgery.This is a single-center prospectively conducted pained CP undergoing P-ESWL. Patients surgery history (PSH) were included PSH group, without during same period assigned control group. primary outcomes complications associated P-ESWL pain relief. Secondary stone clearance improved quality-of-life...
Pediatric patients always suffer from chronic pancreatitis (CP), especially those with steatorrhea. This study aimed to identify the incidence of and risk factors for steatorrhea in pediatric CP. To our best knowledge, there is no document natural history CP.CP admitted center January 2000 December 2013 were enrolled. Patients assigned (< 18 years old) adult group according their age at onset Cumulative rates both groups calculated. Risk identified, respectively.The median follow-up duration...
Background: Pancreatic stones are pathognomonic of chronic pancreatitis (CP). This study aimed to determine the incidence, identify risk factors, and develop a nomogram for pancreatic in CP patients. Methods: Patients with admitted our center from January 2000 December 2013 were enrolled. Cumulative rates after onset diagnosis calculated. randomly assigned, 2:1 ratio, training validation cohort. Based on cohort, factors identified through Cox proportional hazards regression model, was...
Objectives The aim of this study was to establish a standard describe the spatial distribution pancreatic stones in chronic pancreatitis (CP). Methods Two hundred forty-seven CP patients with from June December 2012 were enrolled. Two-dimensional images coronal projection 3-dimensional computed tomography gained. number (n) all and geometric deviation (σ) distances between centroid centroids every stone that represented nonuniformity calculated by Stone Reconstruction Identification...
Objective The pathogenesis of chronic pancreatitis (CP) is not completely clear. With further studies, smoking toxic to the pancreas. This study classified smoking-related CP as a new etiology and defined cutoff smoking. Design Patients with admitted from January 2000 December 2013 were included in study. characteristics compared between patients, drinking group patients who never smoke or drink (control group). cumulative rates steatorrhea, diabetes mellitus (DM), pancreatic pseudocyst...
Abstract Background and aims Cholecystectomy is performed for most gallbladder polyps (GPs). However, cholecystectomy results concerning complications in some patients. For benign GPs, adoption of gallbladder-preserving surgery worth to recommend. We describe our experiences performing polypectomy GPs by embryonic-natural orifice transumbilical endoscopic (E-NOTES) with a gastric endoscopy. Methods This retrospective study patients who underwent E-NOTES endoscopy from April 2018 September...
The study concerns identifying risk factors and developing nomogram for pancreatic pseudocyst (PPC) in idiopathic chronic pancreatitis (ICP) to facilitate early diagnosis.From January 2000 December 2013, ICP patients admitted our center were enrolled. Cumulative incidence of PPC was determined by Kaplan-Meier method. Patients randomized into training group validation a 2:1 ratio. Risk through Cox proportional hazards regression model based on cohort. constructed according factors.Totally,...
We previously reported that antofloxacin-based bismuth quadruple therapy was safe and effective for