A5100396380- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Gastroesophageal reflux and treatments
- Gastrointestinal Tumor Research and Treatment
- Veterinary medicine and infectious diseases
- Metastasis and carcinoma case studies
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Eosinophilic Esophagitis
- Lung Cancer Treatments and Mutations
- Pregnancy and preeclampsia studies
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Spine and Intervertebral Disc Pathology
- Genetic factors in colorectal cancer
- Appendicitis Diagnosis and Management
- Circular RNAs in diseases
- Colorectal and Anal Carcinomas
- Pancreatic and Hepatic Oncology Research
- Spinal Fractures and Fixation Techniques
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Treatments and Studies
- Pancreatitis Pathology and Treatment
- Ovarian cancer diagnosis and treatment
Fujian Medical University
2013-2025
117th Hospital of People's Liberation Army
2020-2024
Xiamen University
2013-2024
Lianyungang Oriental Hospital
2023-2024
Hangzhou Dianzi University
2021-2024
Wuhan University
2024
Renmin Hospital of Wuhan University
2024
82th Hospital of Pla
2020-2023
Shandong Maternal and Child Health Hospital
2021-2023
Xuan Wu Hospital of the Capital Medical University
2023
Placental angiogenesis contributes to the pathogenesis of preeclampsia (PE) that affects 5-8% all human pregnancies. MicroRNA (miRNA) are a class noncoding 21- 25-nucleotide RNA negatively regulate gene expression posttranscriptionly.The aim this study was test hypothesis miRNA differentially expressed in healthy term and PE placentas subclass angiogenesis-associated increased by PE.Total were extracted from villous placental tissues severe preeclamptic Differential analyzed microarray...
Identifying disease-related microRNAs (miRNAs) is an essential but challenging task in bioinformatics research. Much effort has been devoted to discovering the underlying associations between miRNAs and diseases. However, most studies mainly focus on designing advanced methods improve prediction accuracy while neglecting investigate link predictability of relationships In this work, we construct a heterogeneous network by integrating neighborhood information neural predict potential...
This study aimed to assess the knowledge of risk factors and warning symptoms attitude towards gastric cancer screening among general population in China.Hunan province, China PARTICIPANTS: Individuals aged older than 18 years were recruited using a cluster sampling method.A cross-sectional study, pretested structured questionnaire was used participants' awareness cancer.Knowledge level cancer, attitude, sociodemographic associated with behaviour.This comprised 1200 participants mean age...
Most of the previous studies focused on central line-associated bloodstream infection (CLABSI), while non-central (N-CLABSI) was poorly studied. This study performed to investigate clinical impacts and risk factors for N-CLABSI in intensive care unit (ICU) patients. An observational conducted an adult general ICU. The electronic medical records from 2013 2017 all patients aged ≥ 18 years admitted ICU > 2 days were analyzed retrospectively. Patients with without or CLABSI compared features...
Abstract Uncontrollable hemorrhage from deep, narrow wounds poses a critical threat to life, as locating the bleeding arteries in such areas is challenging. Rapid control remains significant challenge pre‐hospital care. Herein, an injectable hemostatic device filled with disc‐like PVA sponges developed for this objective. The pristine sponge strung necklace‐structured loaded foldable injector. With novel retraction mechanism, self‐designed injector precisely deploys deep sites, surpassing...
The purpose of this study was to assess and compare the clinical effectiveness capecitabine monotherapy that combined with oxaliplatin as neoadjuvant chemoradiotherapy during preoperative radiotherapy in management low middle rectal cancer. A retrospective cohort performed. Medical data were collected from individuals locally progressing cancer admitted a regional hospital China. Two groups patients formed for different regimens: group group. Within group, CAPEOX regimen applied 2 rounds...
<title>Abstract</title> Background Good exposure of the submucosal visual field is a prerequisite for successful endoscopic dissection (ESD). There are few reports on ESD training using orthodontic rubber band combined with magnetic ring traction (ORB-MA). This study evaluated efficacy ORB-MA training. Methods utilized an <italic>ex vivo</italic> porcine gastric model. Doctors experienced in mucosal resection (> 100 cases), but not ESD, were randomly divided into conventional and...
Abstract Background Inaccurate Forrest classification may significantly affect clinical outcomes, especially in high risk patients. Therefore, this study aimed to develop a real-time deep convolutional neural network (DCNN) system assess the of peptic ulcer bleeding (PUB). Methods A training dataset (3868 endoscopic images) and an internal validation (834 were retrospectively collected from 900th Hospital, Fuzhou, China. In addition, 521 images four other hospitals used for external...
Abnormalities of the fetal cardiovascular system caused by growth restriction (FGR) may lead to adverse outcomes. The cardiac function assessment is great significance for treatment selection and prognostic evaluation fetuses with FGR.This study aimed explore value HQ analysis based on speckle tracking imaging (STI) evaluate global regional early-onset or late-onset FGR.From June 2020 November 2022, 30 pregnant women FGR (21-38 gestational weeks) in Department Ultrasound, Shandong Maternal...
Objective To explore the relationships between gastric cancer and serum pepsinogen I (PG I), PG II, I/II ratio, gastrin 17 (G-17) Helicobacter pylori infection, to investigate dietary lifestyle risk factors for in Fujian Province, China. Design A hospital-based, 1:1 matched case–control study. Setting Patients with newly diagnosed were recruited from Provincial Hospital No. 900 of Joint Support Force Chinese People’s Liberation Army July 2014 December 2016. Participants total 180 pairs...
Pancreatic fibrosis is one of the most important pathological features chronic pancreatitis (CP), and pancreatic stellate cells (PSCs) are considered to be key cells. Puerarin flavonoid active component in Chinese herb Radix Puerariae , it exhibited anti-fibrotic effect various fibrous diseases recently. However, impact molecular mechanism puerarin on CP remain unknown. This study systematically investigated vivo vitro . H&amp;E staining, Sirius Red qRT-PCR Western blotting analysis...
The objective of this study was to examine the effects n-3 polyunsaturated fatty acids (n-3 PUFAs) on coronary arterial large conductance Ca2+-activated K+ (BK) channel function in smooth muscle cells (SMCs) streptozotocin-induced diabetic rats.The docosahexaenoic acid (DHA) and eicosapentaenoic (EPA) BK open probabilities were determined using patch clamp technique. mRNA protein expressions subunits measured qRT-PCR Western blots. artery tension SMC Ca2+ concentrations a myograph system...
Objective To evaluate the value and compare effectiveness of linked color imaging-based endoscopic grading gastric intestinal metaplasia (LCI-EGGIM) operative link on (OLGIM) in risk stratification early cancer (EGC).Methods Eighty-one patients with EGC who underwent submucosal dissection were included. The general data EGC-related factors all participants recorded. LCI-EGGIM OLGIM used for both groups.Results number score ≥ 5 was significantly higher group than control (58.02% vs. 12.35%, p...
FGF2 (fibroblast growth factor 2), but not vascular endothelial (VEGF), stimulates sustained activation of ERK2/1 for NOS3 (nitric-oxide synthase 3) protein expression in ovine fetoplacental artery cells (oFPAEC). We deciphered herein the downstream signaling responsible by oFPAEC. FGF2, VEGF, increased mRNA levels without altering its degradation. trans-activated sheep promoter, and this was dependent on activation. did trans-activate promoters with deletions upstream consensus AP-1 site...
The efficiency and safety of charcoal nanoparticle tattooing in localizing unpalpable colonic small lesions for later laparoscopy is described. Twenty six patients were enrolled this prospective study. Tumor sites localized with nanoparticles during colonoscopy laparoscopic colorectal operations. In all patients, the entire colon was examined preoperatively by 0.5 ml (5 mg) injected submucosally near or polypectomy sites. During operations these biopsy-proven tumors, tumors easily...
Esophageal capsule endoscopy (ECE) is relatively limited because of poor visualization the distal esophagus. This study aimed to investigate whether string esophageal with real-time viewing (SECE+RTV) could improve Z-line esophagus as compared conventional ECE.Thirty healthy volunteers, aged 20-45 years, were recruited and underwent SECE+RTV ECE sequentially. The main outcome measures included grade air-bubble saliva interference, success rate (frequency visualizing at least three...