Abstract Background Noninvasive diagnostic methods and laboratory parameters play an important role in the activation of Crohn’s Disease (CD). C-reactive protein (CRP) is one best measurements used to evaluate activity CD. Ultrasonography a non-invasive, easily accessible, inexpensive, ionizing radiation-free imaging method that can be performed at bedside. In this study, we aimed compare CRP level intestinal ultrasonography (IUS) findings Methods 79 patients who applied due or for routine...

Metabolic syndrome (MetS) is a clinical condition characterized by central obesity, elevated triglycerides, low-high density lipoproteins, impaired fasting glucose, and hypertension. There insufficient data on the prevalence of MetS in patients with inflammatory bowel disease (IBD). This study sought to determine Turkish cohort IBD association between insulin resistance (IR) parameters, this population.A total 177 over 18 years age (62 Crohn's (CD) 115 ulcerative colitis (UC)) were enrolled...

The aim of this cross-sectional study was to determine sociodemographic and disease related factors affecting the quality life style behavior in patients with heart disease.Data are collected via information form, Healthy Life Style Behaviors Scale, short form-36 scale 325 people disease. T test for independent samples, one-way ANOVA Pearson correlation analyzes used statistical evaluation data.It has been determined that average age 56.98±11.89 years, 58.2% were male, 48.6% graduated from...

We evaluated the effect of zinc treatment on blood-brain barrier (BBB) permeability and levels (Zn), natrium (Na), magnesium (Mg), copper (Cu) in brain tissue during epileptic seizures. The Wistar albino rats were divided into four groups, each as follows: (1) control group, (2) pentylenetetrazole (PTZ) group: treated with PTZ to induce seizures, (3) Zn ZnCl(2) added drinking water for 2 months, (4) + group. brains left, right hemispheres, cerebellum stem regions. Evans blue was used BBB...

Introduction: During the course of systemic inflammation, most immune cell types get activated to a certain degree as part of, or contributing to, cascade physiopathological events.Whether for some cells, classically phagocytes innate system, it is clear that direct sensing pathogen-associated molecular patterns leads activation initiating picture not so natural killer (NK) cells.While NK cells have been shown express toll-like receptors (TLR), role these on NKs during inflammation has...

It was aimed to determine the posttraumatic growth level of patients with hemodialysis and examine supposed effect socio-demographic variables, variables associated disease, perceived social support ways coping. Research data were collected by 491 in private dialysis centers. found that ones who are aware disease primary, secondary or high school graduate well income received initial medication before had showed better Posttraumatic Growth. seen total point Growth Scale sub-scales "Changes...

In the literature, few studies have investigated effects of melatonin on energy metabolism in skeletal muscle endotoxemia. We tissue structure, muscle, and antioxidant level rats with divided into 4 groups, control, lipopolysaccharide (LPS) (20 mg/kg, i.p., single dose), (10 three times), + LPS. Melatonin was injected i.p. 30 min before after 2nd 4th hours LPS injection. Antioxidant status determined by glutathione (GSH) measurement blood. Muscle stained using modified Gomori trichrome...

We aimed to investigate the effects of melatonin administered before and during endotoxemia on lung tissue rats, cytokine, YKL-40, matrix metalloproteinase (MMP) inhibitor levels, oxidative stress parameters, energy balance. Sepsis was induced with lipopolysaccharide (LPS), cell wall molecule gram negative bacteria. Rats were divided into four groups, Control, LPS (Escherichia coli O127:B8, 20 mg/kg), (10 melatonin+LPS (M+LPS). After injections, tissues samples taken for experimental...

Fish oil (FO) and mesalazine have well-known anti-inflammatory antioxidant effects; on the other hand, information related to combined intrarectal administration of FO is limited. The present study was conducted make comparison therapeutic effectiveness rectally administered in rats with trinitrobenzenesulfonic acid (TNBS)-induced colitis. Wistar were randomly assigned 5 groups as (1) Control, (2) Colitis, (3) Colitis + Mesalazine (Colitis M), (4) Oil F), (5) M F). Intrarectally TNBS induced...

The aim of this study was to perform the effects diabetes on permeability blood–brain barrier (BBB) during pentylenetetrazole (PTZ)‐induced epileptic attacks. For propose, animals were divided into four groups. These groups contained intact, PTZ‐treated, diabetic and PTZ‐treated individuals, respectively. To evaluate functioning BBB, Evans blue used as a BBB indicator, expressions zonula occludens‐1 glial fibrillary acidic protein involving determined immunohistochemically. Also, changes in...

In this investigation, the effects of hypoglycemic coma and alcoholic on blood-brain barrier (BBB) permeability have been compared. Female adult Wistar albino rats weighing 180-230 g were divided into three groups: Control group (n=8), Alcoholic Coma Group (n=18), Hypoglycemic (n=12). The animals went approximately 3-4 hours after insulin administration 3-5 minutes alcohol administration. Evans blue (4mL/kg) was injected intravenously as BBB tracer. It observed that did not significantly...

OBJECTIVE: We aimed to investigate the effects of exogenous ghrelin on cytokine and levels, oxidant parameters, apoptotic genes in lung tissue during sepsis.BACKGROUND: There was evidence that changes apoptosis are linked with morbidity mortality sepsis.There were scarce studies effect endogenous levels sepsis.METHODS: Male Wistar albino rats 200-250 g separated into four groups; Control, LPS (5 mg/kg), Ghrelin (10 nmol/kg i.v.), LPS+Ghrelin.Tumor necrosis factor-alpha (TNF-α),...

Galectins constitute of a soluble mammalian β-galactoside binding lectin family, which play homeostatic roles in the regulation cell cycle, and apoptosis, addition to their inflammatory conditions. Galectin-3 has an important role various conditions including endotoxemia, airway inflammation. Statins, key precursor inhibitors 3-hydroxyl-3-methyl coenzyme A (HMG-CoA) reductase, may prevent progression inflammation sepsis after prior statin treatment. Endotoxemia leads formation oxidative...

Non-invasive methods play an important role in clinical assessment of Crohn's disease. Recent studies have highlighted the effectiveness and reliability intestinal ultrasonography. We aimed to examine relationship between ultrasonography clinical, endoscopic, computed tomography enterography findings, assess activity disease.This was a 1-year prospective study involving patients diagnosed with Disease. Clinical endoscopic indi- ces, findings were evaluated. Intestinal wall thickness, mes-...

Objectives: Folic acid (FA) is physiologically important in mammals and a common vitamin supplement used during pregnancy lactation. Numerous studies have reported that FA significantly improves endothelial function. The blood–brain barrier (BBB) plays an role maintaining the microenvironment required for neuronal function, but its unique structure damaged by epileptic seizures. aim of this study was to evaluate potential protective on BBB leakage, as well reactive astrogliosis pregnant rats...

Background: The aim of the study is to assess correlation between a new antibody panel that developed against glycans on Crohn's disease (CD) and ulcerative colitis (UC) differentiative diagnosis properties. Methods: In study, 137 CD 122 UC patients 90 controls were included. Anti-saccharomyces cerevisiae IgG (ASCA), anti-laminaribioside (ALCA), anti-chitobioside IgA (ACCA), anti-mannobioside (AMCA) tested in serum. Results: While at least 1 other 3 serological markers was positive 89%...

Sınava giren öğrencilerin başarılarını etkileyen durumlardan biri sınav kaygısıdır. Bu sorunu ortadan kaldırmak amacıyla birçok çalışma yapılmış; özellikle de son dönemlerde teknolojinin etkisi araştırılmıştır. Ancak net bir sonuca ulaşılamamıştır. nedenle araştırmada, teknoloji içerikli Kahoot ve klasik yöntemlerinin, kaygısı üzerinde herhangi farklılık oluşturup oluşturmadığını ortaya koymak amaçlanmıştır. 
 Çalışma karşılaştırmalı, deneysel olup ön-son test yöntemi uygulanmıştır....

It has been reported that changes in cytokine levels affect mitochondrial functions, of hypoxia-inducible factor α (HIF-1α), and tissue damage during sepsis. We aimed to investigate the effects simvastatin pretreatment on enzyme activities, ghrelin, HIF-1α, thiobarbituric acid reactive substances (TBARS) kidney Rats were separated into four groups, namely, control, lipopolysaccharides (LPS) (20 mg/kg), + LPS. measured activities TBARS using spectrophotometry. The histological structure...