A5066925885- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Memory Processes and Influences
- Educational Strategies and Epistemologies
- Ophthalmology and Visual Impairment Studies
- Visual and Cognitive Learning Processes
- Retinal Development and Disorders
- Family Support in Illness
- Urological Disorders and Treatments
- Retinal Diseases and Treatments
- Maternal Mental Health During Pregnancy and Postpartum
- Renal cell carcinoma treatment
- Bone fractures and treatments
- Cancer, Hypoxia, and Metabolism
- Psychological and Educational Research Studies
- Pain Management and Opioid Use
- Radiopharmaceutical Chemistry and Applications
- Anesthesia and Pain Management
- Urinary and Genital Oncology Studies
- Hip disorders and treatments
- Perfectionism, Procrastination, Anxiety Studies
- Cutaneous Melanoma Detection and Management
- Potassium and Related Disorders
- Intelligent Tutoring Systems and Adaptive Learning
Durham VA Health Care System
2021-2025
Kent State University
2018-2023
Durham VA Medical Center
2021-2023
Duke University
2023
Veterans Health Administration
2022
University Hospitals of Cleveland
2019-2021
Center for Clinical Research (United States)
2021
University Hospitals Cleveland Medical Center
2020
University School
2020
Case Western Reserve University
2020
318 Background: We previously showed that men with MHI are 20% less likely to be diagnosed PC, but when diagnosed, nearly 2x more have aggressive PC compared non-MHI (ASCO 2023). Subsequently, we prior Dx receive definitive treatment (DTx) however poorer post-Tx surveillance adherence and increased risk of biochemical recurrence (BCR; ASCO 2024). However, among whether impacts or outcomes has yet determined. The objective was test the association between (i) Tx time from receipt DTx, (ii)...
When learners make judgments of learning (JOLs) for some word pairs but not others, how and why is recall performance affected? Participants studied related unrelated made JOLs a randomly selected half the pairs. We evaluated two hypotheses. The changed-goal hypothesis states that making leads to notice differences in pair difficulty change their goal. Because are manipulated within participants, such goal should influence all (judged or non-judged) processed on list, which lead no JOL...
•This study reports a novel automated approach to quantify progression of visual dysfunction.•This was validated relative manual grading.•The rate at the disease front in Stargardt is reported.•The new method may allow shorter clinical trials or smaller cohorts both. PurposeMean sensitivity (MS) derived from standard test grid using microperimetry sensitive outcome measure investigating treatments for degenerative retinal diseases. This hypothesizes that functional decline faster edge dense...
The Oncotype DX Genomic Prostate Score (GPS) assay has been validated as a strong prognostic indicator of adverse pathology, biochemical recurrence, distant metastasis (DM), and prostate cancer (PCa)-related death (PCD) in men with localized PCa after radical prostatectomy. However, it yet to be tested undergoing external beam radiation therapy (EBRT), for whom assessing progression risk could inform decisions on treatment intensity. We analyzed whether GPS results are associated time...
Importance To date, limited data exist regarding the association between Agent Orange and bladder cancer, Institute of Medicine concluded that exposure to cancer outcomes is an area needed research. Objective examine risk among male Vietnam veterans. Design, Setting, Participants This nationwide Veterans Affairs (VA) retrospective cohort study assesses 2 517 926 veterans treated in VA Health System from January 1, 2001, December 31, 2019. Statistical analysis was performed 14, 2021, May 3,...
Objective: To assess clinical, radiographic, and functional outcomes after intramedullary nail (IMN) fixation of tibia fractures with an infrapatellar approach compared to a suprapatellar approach. Design: Retrospective chart review. Setting: Level 1 trauma center. Patients/Participants: Two hundred four patients 208 treated nailing between 2008 2018. Methods: A retrospective review was conducted. The clinical IMN were groups versus Multivariate models created control for confounding...
Low serum magnesium level has been shown to be associated with increased mortality, but its role as a predictor of cardiovascular disease is unclear. This study evaluates the association between and events all-cause mortality in large cohort individuals chronic kidney (CKD).
Abstract Objective Targeted intrathecal drug delivery (TIDD) is an effective interventional pain management modality often used in postlaminectomy patients with refractory chronic low back pain. A combination of bupivacaine opioid used. However, catheter tip granulomas have occurred use morphine or hydromorphone but generally not fentanyl. The objective this study was to compare the efficacy TIDD using bupivacaine/fentanyl vs bupivacaine/hydromorphone intractable postlaminectomy. Materials...
Abstract Background We previously reported that outcomes after radical prostatectomy (RP) were similar among non‐Hispanic Black, White, and Hispanic White Veterans Affairs (VA) patients. However, prostate cancer (PC) mortality in Puerto Rican Hispanics (PRH) may be higher than other groups. Data focused on PRH patients is sparse; thus, we tested the association between PR ethnicity RP. Methods Analysis included men SEARCH cohort who underwent RP (1988–2020, n = 8311). ( 642) treated at VA,...
Abstract Background This study was conducted to better characterize the epidemiology, clinical outcomes, and current treatment patterns of de novo oligometastatic hormone‐sensitive prostate cancer (omHSPC) in United States Veterans Affairs Health Care System. Methods In this observational retrospective cohort study, 400 metastatic PC (mHSPC) patients diagnosed from January 2015 December 2020 (follow‐up through 2021) were randomly selected. omHSPC defined as five or less total metastases...
Making judgments of learning (JOLs) while studying related word pairs can enhance performance on tests that rely cue-target associations (e.g., cued recall) compared to alone. One possible explanation for this positive JOL reactivity effect is the prompt make JOLs, which typically occurs halfway through presentation each pair, may encourage learners devote more attention pair during second half encoding episode, contribute enhanced recall performance. To investigate idea, an online sample...
To describe patient characteristics and pathological stage at bladder cancer (BCa) diagnosis in a diverse population within national, equal-access healthcare system.
Summary Successive relearning combines two effective learning techniques (retrieval practice and spaced practice) involves practicing retrieval until some level of mastery has been reached (i.e., at least one correct attempt) in each multiple sessions. Several laboratory studies have demonstrated the promise successive for enhancing student learning, but attempts to evaluate its effectiveness authentic educational contexts are limited. In current research, we implemented a difficult...
It is well established that young infants have the highest risk of severe pertussis, which often results in hospitalization. Since 2012 recommendation administering tetanus toxoid, diphtheria and acellular pertussis (Tdap) vaccine for every pregnancy, evaluation hospitalizations among United States has been limited.In this ecological study, we used Kids' Inpatient Database, largest all-payer pediatric inpatient database States, to study <1 month age from 2000 2016.The overall rate before...
<h3>Purpose</h3> Sensitive, reproducible visual function biomarkers are necessary to evaluate the efficacy of emerging treatments for Stargardt disease type 1 in clinical trials. We previously demonstrated that fixation stability may serve as a secondary outcome parameter loss. However, test duration and protocol have an unknown effect on assessment stability. Here, we hypothesize separate testing with single target is different from combined using same simultaneous perimetry testing....
Recent reports with a small number of patients showed an association red blood cell distribution width (RDW) prostate cancer (PCa) progression.To investigate whether preoperative RDW can serve as prognostic marker in PCa undergoing radical prostatectomy (RP) large, equal access, and diverse patient cohort.Data were retrospectively collected on 4756 men treated RP at eight Veteran Affairs medical centers within the Shared Equal Access Regional Cancer Hospital (SEARCH) database from 1999...
Recently, a skeletal maturity system using knee radiographs, named the modified Roche-Wainer-Thissen (RWT) system, has been developed 7 discrete radiographic parameters. While shown to significantly outperform Greulich and Pyle atlas, effect of rotational variation radiograph on determinations not studied.Normal computed tomography scans 12 male children ages 10 16 years 8 female 14 were obtained retrospectively, converted into 3-dimensional reconstructions, then used simulate radiographs in...