A5084113403- Adipokines, Inflammation, and Metabolic Diseases
- COVID-19 Clinical Research Studies
- Extracellular vesicles in disease
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Dermatological and COVID-19 studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Lomonosov Moscow State University
2021-2023
Moscow State University
2021
Pulmonary fibrosis is a common and threatening post-COVID-19 complication with poorly resolved molecular mechanisms no established treatment. The plasminogen activator system, including urokinase (uPA) receptor (uPAR), involved in the pathogenesis of COVID-19 contributes to development lung injury pulmonary fibrosis, although their cellular underpinnings still remain obscure. aim current study was assess role uPA uPAR fibrosis. We analyzed expression human tissues from patients using...
The coronavirus disease 2019 (COVID-19) pandemic requires not only the creation of vaccines to prevent spread disease, but also development novel drugs aimed at reducing viral load, suppressing an excessive immune response and preventing severe complications such as lung fibrosis acute respiratory distress syndrome. One promising targets for studying pneumonia, systemic inflammation disseminated intravascular coagulation in COVID-19 is plasminogen activator system. In patients with a course,...