A5084474249- Neurological Disorders and Treatments
- Human Health and Disease
- Biochemical effects in animals
- Neurological Disease Mechanisms and Treatments
- Alzheimer's disease research and treatments
- Viral Infections and Vectors
- Amoebic Infections and Treatments
- Yersinia bacterium, plague, ectoparasites research
- Viral Infections and Outbreaks Research
- Bacillus and Francisella bacterial research
- Medical and Biological Ozone Research
- Zoonotic diseases and public health
- Mosquito-borne diseases and control
- Mycorrhizal Fungi and Plant Interactions
- T-cell and B-cell Immunology
- Pancreatitis Pathology and Treatment
- Healthcare Systems and Public Health
- Birth, Development, and Health
- Bone Tissue Engineering Materials
- Apelin-related biomedical research
- Lichen and fungal ecology
- Breast Cancer Treatment Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Historical Medical Research and Treatments
- Antifungal resistance and susceptibility
Kharkiv National Medical University
2018-2025
Kharkiv Medical Academy of Postgraduate Education
2019
Institute of Basic Biological Problems
2005-2014
Institute of Clinical and Experimental Medicine
2010
Russian Academy of Sciences
2008
Medical University of Sofia
2003
All-Russian Research Institute of Agricultural Microbiology
1994
The killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop (IHIWS) sought to explore worldwide population variation in KIR loci, and examine relationship between genes their human leukocyte antigen (HLA) ligands. Fifteen laboratories submitted genotype HLA ligand data 27 populations from six broad ethnic groups. Data were analyzed for correlations frequencies known In addition, allelic typing was performed KIR2DL2 3DL1 a subset...
Mucormycosis is a serious life-threatening opportunistic infection which characterized by various clinical and morphological manifestations, rapid pro gression, unpredictable course high mortality. The development of mycormycosis depends on the metabolic immune status human body. authors conducted analysis case rhinocerebral mucormycosis in patient who was diagnosed lifetime, but despite set therapeutic surgical measures led to death, due severity pathology, late hospitalization presence...
Background. Despite numerous studies, the assessment of functional state vascular endothelium by determining localization cells, producers endothelial proliferation factor, and measuring intensity its production in brain rats with dementia Alzheimer type is great relevance.
 Objective: to investigate impact mesenchymal stem cells on vessel Alzheimer-type assessing optical density structures expressing factor.
 Results. In neurons CA1 zone hippocampus gr. SС-14 SС-28, SС-28-MSC,...
Phenotypic properties (growth characteristics, utilization of carbon and nitrogen sources, intrinsic antibiotic resistance) 53 Rhizobium strains isolated from root nodules the temperate-zone legumes Astragalus spp. (29 strains), Oxytropis campanulata (7 Hedysarum alpinum Ononis arvensis (3 Glycyrrhiza (4 Coronilla varia strains) were compared with those other Rhizobium, Brady rhizobium, Agrobacterium strains. The final matrix, containing 83 56 nonsymbiotic features, was used for computer...
The aim of this investigation was to study the effect doping steroid nandrolone on metamizol and morphine-induced analgesia tolerance/dependence in rats. Nandrolone per se did not change basal nociceptive thresholds both sexes. It diminished analgesic females, revealed by tail flick test, males, paw pressure hot plate tests. In general, action decrease female male This strongly manifested tests male, animals. slowed development opioid tolerance/dependence. aggravated withdrawal syndrome...
In experimental conditions, at different times (14th, 30th, 90th, 180th, and 360th day), with the help of modern methods, general effect on body rats implants for osteosynthesis based polylactide calcium phosphate was investigated ceramics comparison control, it established that: composite material, in general, does not affect somatic status animals all terms experiment. The content activity biochemical markers regenerative-inflammatory process (glycoproteins, chondroitin sulfates, alkaline...
Background. In orthopedics and traumatology, polymer materials that are resorbed dissolve in biological fluids occupy a significant place as screws fixation pins, plates anchors, cages. Most often, implants from L-polylactic acid (PLA) used. It is possible to increase their quality by including ceramic into composition, particular tricalcium phosphate (TCF) hydroxylapatite (HA). However, with different percentages compositions of material differ strength behavior bone. The purpose was check...
The hematoophthalmic barrier is one of the mechanisms resistance that serves to protect body and prevents homeostasis disorder when affected by factors can disturb this balance. One complications mechanical trauma eye violation appearance oxidative stress on background general inflammatory process in cellular structures. Objective: study dynamics catalase activity heart muscle tissue rats under caused action barrier. Materials methods. was carried out white neonatal mature healthy male six...
Background. The last researches offer to conduct the study of Alzheimer disease (AD) mechanisms using diverse experimental models. However, it was not investigated behavioral and cognitive impairment in rats at different stages vascular model dementia Alzheimer’s type developed by us.
 Subjects methods. experiment performed on 32 male WAG weighing 180-250 g which were divided into 4 groups. Rats from group 1 3 injected aqueous solution sodium nitrite a dose 50 mg/kg body mass...
На моделі хронічного стресу спричиненого довготривалою іммобілізацією щурів-самиць в період вагітності, встановлено, що у тканині підшлункової залози і сироватці крові не тільки їх самих, а й одно- та двохмісячного потомства відзначається зсув основних показників оксидантно-антиоксидантного гомеостазу, що, можливо є результатом реалізації нейрогуморальної відповіді організму на стрес. Ці зміни ідентичними тварин, інформативність гомеостазу сироватки крові, використовується для кращого...