A5036246907- Supramolecular Self-Assembly in Materials
- Advanced Sensor and Energy Harvesting Materials
- Hydrogels: synthesis, properties, applications
- Luminescence and Fluorescent Materials
- Advanced Polymer Synthesis and Characterization
- Conducting polymers and applications
- Polymer composites and self-healing
- Supercapacitor Materials and Fabrication
- Polydiacetylene-based materials and applications
- Silk-based biomaterials and applications
- Click Chemistry and Applications
- Cancer Genomics and Diagnostics
- Supramolecular Chemistry and Complexes
- Polymer Surface Interaction Studies
- Advanced Materials and Mechanics
- Metal-Organic Frameworks: Synthesis and Applications
- Chemical Synthesis and Analysis
- Surfactants and Colloidal Systems
- Photochromic and Fluorescence Chemistry
- biodegradable polymer synthesis and properties
- Photoreceptor and optogenetics research
- Surgical Sutures and Adhesives
- Synthetic Organic Chemistry Methods
- Bacterial Genetics and Biotechnology
- Electrocatalysts for Energy Conversion
Ningbo University
2016-2025
Wuhan University of Technology
2023
University of Illinois Urbana-Champaign
2017-2022
Tibet Autonomous Region People's Hospital
2018-2022
Nanyang Normal University
2020-2022
National Cancer Institute
2021
Harvard University Press
2012-2019
Center for Cancer Research
2019
Soochow University
2019
Beijing National Laboratory for Molecular Sciences
2011-2017
The synthesis and characterization of new thermoresponsive pegylated poly-l-glutamate (poly-l-EGxGlu) are described. obtained polypeptides display low critical solution temperature (LCST) behaviors in water, the LCST can be tuned via copolymerization different amino acid monomers at varied molar ratio. This is first example polypeptide made from ring-opening polymerization α-amino N-carboxyanhydrides (NCAs). Circular dichroism characterizations reveal that secondary structure poly-l-EGxGlu...
Inspired by assemblies in the natural world, researchers have prepared diverse suprastructures with distinct spatial arrangements artificial self-assembly, including micelles, vesicles, ribbons, films, fibers, and tubes. The field of assembly is undergoing a transition from single-component to multicomponent single-step multistep processing. Control over size, shape, composition these building blocks has enabled formation substantial structural diversity. More importantly, harnessing...
Breakthrough to the extreme properties of polymer networks relies on new insights into their molecular dynamics. Time-salt concentration superposition has been discovered in polyelectrolyte coacervate systems, proving instrumental tuning mechanical performance hydrogels. However, time-salt type never mentioned existing literature. Herein, we reported that poly(methacrylamide) (PMAm) hydrogel can be systematically regulated a vast range by treating with different salts, for example, Young's...
Thermoresponsive hydrogel actuators have attracted tremendous interest due to their promising applications in artificial muscles, soft robotics, and flexible electronics. However, most of these materials are based on polymers with lower critical solution temperature (LCST), while those from upper (UCST) rare. Herein, we report a multiple-responsive UCST actuator the complex poly(acrylic acid) (PAAc) poly(acrylamide) (PAAm). By applying heterogeneous photopolymerization, bilayer was obtained,...
Significance Biomacromolecules are synthesized in cells with high precision, although the cellular environment contains numerous molecules and species other than building blocks. In contrast, even state-of-the-art chemical synthesis of macromolecules is exclusively carried out under a specific condition containing only clean, essential starting materials to minimize side reactions. Inspired by ribozyme-catalyzed protein synthesis, we report here controlled polypeptide nonpurified N...
Hybrid hydrogels based on electrostatic co-assembly of polyoxometalates and ABA triblock copolymers were readily prepared exhibit excellent luminescence self-healing performance.
We demonstrate that a tripeptide hydrogelator, Nap-FFG, can selectively self-assemble at the surface of platelets, thus inhibiting ADP-, collagen-, thrombin- and arachidonic acid (AA)-induced human platelet aggregations with IC(50) values 0.035 (41), 0.14 (162), 0.062 (68), 0.13 mg/mL (148 μM), respectively. Other hydrogelators chemical structures Nap-FFX (X = A, K, S, or E) could not possessed less potencies to inhibit aggregations. observed higher amounts Nap-FFG by techniques LC-MS...
Cubic metallacages were arranged into multidimensional (one-, two-, and three-dimensional) suprastructures via multistep assembly. Four new shape-controllable, hybrid with modified substituents tunable electronic properties prepared using dicarboxylate ligands various (sodium sulfonate, nitro, methoxyl, amine), tetra-(4-pyridylphenyl) ethylene, cis-(PEt
Cooperative interactions and transitions are among the most important strategies utilized by biological systems to regulate a variety of physical chemical processes. We report herein an auto-accelerated, rapid cooperative polymerization N-carboxyanhydrides (NCAs) with initiators structurally as simple linear aliphatic diamines for synthesis polypeptides. The initiated proceeds via formation "hinged" polypeptides, which two blocks helical chains connected head-to-head diamine molecules in...
Poly(ethylene glycol)-block-poly(γ-(2-methoxyethoxy)esteryl-L-glutamate) (PEG-b-poly-L-EG2Glu) was synthesized via ring-opening polymerization (ROP) of L-EG2Glu N-carboxyanhydride (NCA) using PEG-NH2 as macroinitiator. This diblock contained a thermo-responsive poly-L-EG2Glu block, which adopted primarily helical conformation in pristine aqueous solution. We found that PEG-b-poly-L-EG2Glu can display two levels self-assembly behaviors associated with hydrophobic interactions and...
3D hierarchical Ni(PO<sub>3</sub>)<sub>2</sub>nanosheet arrays are developed as a novel electrode material with superior energy storage behavior.
Despite rapid progress in recent years, it has remained challenging to prepare well-defined metal–organic complex-based suprastructures. As a result, the physicochemical mechanisms leading their geometrical complexity remain perplexing. Here, porphyrin-based metallacage was used as building block construct octahedra via self-assembly, and mechanism for evolution of metallacages into disclosed by both experiments theoretical simulations.
The adhesion to wet, acidic, and saline biointerfaces with large deformation is important in the fields of wound dressing motion monitoring but has proven be extremely challenging. There a need for facile method improve stretchability salt resistance simultaneously. Here, an ultrastretchable, pH-tunable, surface-adaptive, salt-resistant hydrogel adhesive reported. prepared through cross-linking acrylamide supramolecular complex poly(β-cyclodextrin) (PCD) benzimidazole (BI). dynamic...
Bioadhesives have garnered widespread attention in the biomedical field, for wound healing and tissue sealing. However, challenges exist due to inferior performance of bioadhesives, including weak adhesion, poor biocompatibility, or lack biodegradability. In this work, we demonstrate fabrication hydrogel adhesive based on polypeptides composed lysine glutamic acid. The cation−π interaction between ammonium cations phenyl groups endows with strong cohesion, hydrophobicity group significantly...
Bioadhesives have emerged as versatile and powerful tools for tissue repair integration with biomedical devices, offering a wide range of applications that captured significant clinical scientific interest. Synthetic polypeptide adhesives are particularly promising candidates bioadhesives, but often face limitations in adhesive strength. In this study, inspired by marine proteins, the secondary structure hydrophobic–hydrophilic balance polypeptides were precisely regulated to transform...
Three alkyl-polypeptide (AP) amphiphiles were prepared using ring-opening polymerization of α-amino acid N-carboxyanhydride. The polypeptide segment was composed diethylene-glycol-monomethyl-ether-functionalized poly-L-glutamate (poly-L-EG(2)Glu). These AP can spontaneously self-assemble into transparent hydrogels in water. showed shear thinning properties, and their strength be modulated by hydrophobic alkyl tails. CryoTEM AFM characterizations suggested that these formed nanoribbons...
Easy regenerability of core components such as electrode and electrolyte is highly required in advanced electrochemical devices. This work reports a reliable, regenerable, stretchable hydrogel based on ionic bonds between polyacrylic acid (PAA) polyallylamine (PAH). PAA-PAH (1M LiCl addition) exhibits high conductivity (0.050 S·cm-1) excellent mechanical property (fracture strain 1,688%). Notably, the can be regenerated to any desired shape under mild conditions remains 96% 90% initial after...