A5100613133- biodegradable polymer synthesis and properties
- Electrospun Nanofibers in Biomedical Applications
- 3D Printing in Biomedical Research
- Microfluidic and Bio-sensing Technologies
- Microplastics and Plastic Pollution
- Advanced Sensor and Energy Harvesting Materials
- Polymer Surface Interaction Studies
- Cellular Mechanics and Interactions
- Genomics, phytochemicals, and oxidative stress
- Organic Electronics and Photovoltaics
- Microfluidic and Capillary Electrophoresis Applications
- Additive Manufacturing and 3D Printing Technologies
- Nanofabrication and Lithography Techniques
- Conducting polymers and applications
- Microbial Metabolic Engineering and Bioproduction
- Pluripotent Stem Cells Research
- Bone Tissue Engineering Materials
- Neuroscience and Neural Engineering
- NF-κB Signaling Pathways
- Enzyme Catalysis and Immobilization
- Hydrogels: synthesis, properties, applications
- Thin-Film Transistor Technologies
- Advanced Polymer Synthesis and Characterization
- Electrohydrodynamics and Fluid Dynamics
- Tissue Engineering and Regenerative Medicine
Wonkwang University
2021-2023
Pohang University of Science and Technology
2012-2020
Pusan National University
2012-2014
Chungnam National University
2002-2008
The University of Texas MD Anderson Cancer Center
2003-2007
Dong-Eui University
2007
Although previous studies suggest that nanotopographical features influence properties and behaviors of stem cells, only a few have attempted to derive clinically useful somatic cells from human pluripotent using nanopatterned surfaces. In the present study, we report polystyrene nanopore-patterned surfaces significantly promote pancreatic differentiation embryonic induced cells. We compared different diameters nanopores showed 200 nm highly upregulated expression PDX1, critical...
This study investigates the effects of low shear stress (0.01 Pa and 0.1 Pa) on pre-osteoblastic cell line behaviors using a specially designed generating microchannel system.
Reactive oxygen species (ROS) have been implicated in the pathogenesis of a wide range acute and long-term neurodegenerative diseases. This study was undertaken to examine efficacy Pogostemon cablin, well-known herb Korean traditional medicine, on ROS-induced brain cell injury. cablin effectively protected human neuroglioma line A172 against both necrotic apoptotic death induced by hydrogen peroxide (H(2)O(2)). The effect dose dependent at concentrations ranging from 0.2 5 mg ml(-1)....
Context: Schizandra chinensis Baill (Magnoliaceae) fruit extract (SCE) is considered a traditional herbal medicine for the treatment and alleviation of various diseases. Gastric cancer second most common cause cancer-related death worldwide, first in Korea.Objectives: This study investigates mechanism SCE-induced apoptosis AGS human gastric cells.Materials methods: SCE concentrations from 100 to 400 µg/ml were used. Cell viabilities determined using MTT assay. Members Bcl-2 family Bax...
Cell migration is crucial in physiological and pathological processes such as embryonic development wound healing; strongly guided by the surrounding nanostructured extracellular matrix. Previous studies have extensively studied cell on anisotropic nanotopographic surfaces; however, only a few reported isotropic surfaces. We herein, for first time, propose novel concept of adherable area using nanopore surfaces with sufficient depth adopting high aspect ratio. As pore size surface was...
Human adipose-derived stem cells (hADSCs) can differentiate into various cell types depending on chemical and topographical cues. One cue recently noted to be successful in inducing differentiation is the nanoengineered polystyrene surface containing nanopore array-patterned substrate (NP substrate), which designed mimic nanoscale features of extracellular matrix. In this study, efficacies NP flat substrates neural hADSCs were examined by comparing their substrate-cell adhesion rates,...
In this study, we fabricated and fully characterized a new type of polystyrene (PS) cell-culture platform containing nanoengineered surfaces (NES), referred to as nano Petri dish, which can be used at the transition stage basic cell–NES interaction studies for clinical applications. Nano-injection molding in study was mass production dish having nanopore arrays. The effects processing parameters injection on replication quality arrays were quantitatively evaluated by means design experiments...
Abstract Recently, the importance of surface nanotopography in determination stem cell fate and behavior has been revealed. In current study, we generated polystyrene cell-culture dishes with an omnidirectional nanopore arrayed (ONAS) (diameter: 200 nm, depth: 500 center-to-center distance: nm) investigated effects on rat neural cells (NSCs). NSCs cultured ONAS proliferated better than those flat when density was low showed less spontaneous differentiation during proliferation presence...
In this study, we narrowly define the fidelity of additive manufacturing (AM) as reliability morphology and mechanical properties fabricated structure. The structural design fabrication three-dimensional (3D) printed scaffolds produced using an extrusion technique for bone regeneration are actively studied with respect to their fidelity. However, fabricating ideal is difficult because its intrinsic limitations in tissue engineering, such those regarding resolution, error, printability. Among...