A5009117622- Hematopoietic Stem Cell Transplantation
- Platelet Disorders and Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Suicide and Self-Harm Studies
- Endometrial and Cervical Cancer Treatments
- Acute Myeloid Leukemia Research
- Lymphoma Diagnosis and Treatment
- Psychosocial Factors Impacting Youth
- Child and Adolescent Psychosocial and Emotional Development
- Health and Wellbeing Research
- Diverse Approaches in Healthcare and Education Studies
- Chronic Lymphocytic Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Endometriosis Research and Treatment
- Malaria Research and Control
- Chemotherapy-related skin toxicity
- Ovarian cancer diagnosis and treatment
- Blood properties and coagulation
- Blood groups and transfusion
- Renal Diseases and Glomerulopathies
- Mesenchymal stem cell research
- Bullying, Victimization, and Aggression
- Peptidase Inhibition and Analysis
- Eosinophilic Disorders and Syndromes
Chonnam National University Hospital
1998-2024
Gongju National Hospital
2015-2024
Chonnam National University Hwasun Hospital
2005-2019
Rocky Mountain Cancer Centers
2016
Princess Margaret Cancer Centre
2016
Research Network (United States)
2016
The University of Texas MD Anderson Cancer Center
2016
Korea Institute of Radiological and Medical Sciences
2009
Chonnam National University
1998-2006
To compare disease-free survival (DFS) after maintenance therapy with the selective protein kinase C β (PKCβ) inhibitor, enzastaurin, versus placebo in patients diffuse large B-cell lymphoma (DLBCL) complete remission and a high risk of relapse first-line therapy.This multicenter, phase III, randomized, double-blind, placebo-controlled trial enrolled who were at recurrence rituximab-cyclophosphamide, doxorubicin, vincristine, prednisone (R-CHOP). Patients (N = 758) stage II bulky or III to...
This retrospective study concerns non-bacterial infections in Asian patients receiving alemtuzumab. The clinical data of 182 treated with alemtuzumab alone or alemtuzumab-containing chemotherapy between the years 2003 and 2009 was collected from six countries. Alemtuzumab used setting frontline (n =48) salvage =90) treatment, as a part conditioning regimen for allogeneic stem cell transplant =44). Reactivation cytomegalovirus (66/182) varicella zoster virus (25/182), fungal infection...
This study was conducted to verify whether the response high-dose intravenous immune globulin (IVIG) related effect of splenectomy in chronic idiopathic thrombocytopenic purpura (ITP) patients. A total 79 patients over 16 years age were enrolled this study. The treatment classified on basis platelet count as no (NR, <50 × 109/l), incomplete (IR, (50–150) and complete (CR, >150 109/l). evaluated after infusion IVIG, within 2 weeks (immediate response), during a follow-up period more than 6...
A refractory and resistant disease to conventional induction chemotherapy relapsed are considered as the most important adverse prognostic factors for acute myeloid leukemia (AML). Sixty-one patients (median age, 33.6 yr) with or AML were treated FLAG regimen that consisted of fludarabine (30 mg/m(2), days 1-5), cytarabine (2.0 g/m(2), 1-5) granulocyte colony-stimulating factor. Of 29 (47.5%) achieved complete remission (CR). Higher CR rates observed a first second relapse compared primary...
Abstract Pomalidomide is a third generation immunomodulatory drug which in combination with dexamethasone, has been shown to be active relapsed/refractory multiple myeloma. However, the data Asian patients remain limited. We conducted prospective phase two clinical trial major cancer centers Singapore, South Korea, Taiwan, Japan and Hong Kong assess efficacy safety of pomalidomide dexamethasone (PomDex) +/− cyclophosphamide myeloma who failed lenalidomide bortezomib. Patients were treated (4...
The purpose of this study was to evaluate the effects a school bullying prevention camp for adolescent perpetrators chool violence.A total 95 adolescents (boys=73, girls=22) were included in study. changes after program evaluated using several self-rating scales assessment degree depression, loneliness, impulsivity, self-esteem, and interpersonal reactivity compared with baseline scales.The significantly reduced depression severity (z=-5.874, p<0.001) impul- sivity scale (z=-3.861, p<0.001),...
ACKD has been described mainly in patients treated with hemodialysis(HD), and there are only a few reports about the prevalence of continuous ambulatory peritoneal dialysis (CAPD) patients. Therefore, we compared receiving HD CAPD, evaluated possible factors which may affect development ACKD.Forty nine 49 CAPD who had received therapy for at least 12 months were enrolled this cross-sectional study. Patients past history polycystic kidney disease acquired cystic on predialysis sonographic...
Malignant lymphoma can involve the cardiac cavity or myocardium as a mass. Clinical symptoms of its involvement are usually absent nonspecific, making diagnosis very difficult before death. We experienced patient with secondary myocardial non-Hodgkin's presenting sustained ventricular tachycardia (VT) primary clinical problem. A 39-yr-old woman visited our hospital because dyspnea and palpitation for 7 days. Physical examination revealed rapid heart beat variable intensity first sound soft...
Myung Jin Jo, MD, Jee Won Lee, Minje Sung, PhD, Sook Hyung Song, Young Moon Je Jung Sun Mi Cho, Kyoung Park, and Yun Shin, PhD 1 Department of Psychiatry Behavioral Sciences, Ajou University School Medicine, Suwon, Korea Business, University, Yong-In Mental Hospital, Yongin, Gongju National Gongju, Suwon Child & Adolescent Community Health Service Center,
This study aimed to investigate the clinical characteristics of adolescents hospitalized through emergency room for intentional self-harm or suicide attempts.This retrospective used data from Korean National Hospital Discharge In-depth Injury Survey conducted between 2006 and 2018 individuals aged 10-24 years. The patients were analyzed compared across sex age groups using Rao-Scott chi-square tests multiple logistic regression analysis complex survey data.The most common psychiatric...
Background/Aims: The purpose of this study was to determine the correlations between inflammatory factors—including absolute lymphocyte count, lactate dehydrogenase, β2-microglobulin, albumin, C-reactive protein, and ferritin—and prognosis for survival in patients with multiple myeloma (MM) treated induction chemotherapy containing thalidomide who underwent autologous stem cell transplantation (ASCT). Methods: Data from at 13 university hospitals South Korea were collected retrospectively...
Purpose: To investigate clinical outcomes, response to treatment, and the related factors of recurrence complication, following treatment primary conjunctival malignant lymphoma.Methods: The medical records 39 patients diagnosed with lymphoma between January 2005 June 2013 were retrospectively reviewed.Results: mean age was 51.1 years old.The most common presenting symptom hyperemia (33.3%).The anatomical location mass fornix (38.5%) 25.6% had bilateral involvement.Histopathologically,...
Multiple myeloma (MM) is the second most common haematological cancer worldwide. Along with related diseases including monoclonal gammopathy of undetermined significance (MGUS), plasma cell leukaemia (PCL) and plasmacytoma, MM incidence rising, yet it remains incurable represents a significant disease burden. Clinical registries can provide important information on management outcomes, are vital platforms for clinical trials other research. The Asia-Pacific Myeloma Related Diseases Registry...
Xanthogranulomatous cholecystitis (XGC) is an uncommon, focal or diffuse destructive inflammatory disease of the gallbladder that assumed to be a variant conventional chronic cholecystitis. A 36-year-old male was admitted Chonnam National University Hospital with 10-day history right upper quadrant pain fever. 15 years ago, he first diagnosed as having hemophilia A, and has been followed up in department Hematology. Computed tomogram (CT) revealed well-marginated, uniform, marked wall...
Background: The autosomal dominant giant platelet syndromes (GPS), characterized by triads of platelets, thrombocytopenia, and Döhle-like leukocyte inclusions are caused MYH9 mutation, a gene encoding the nonmuscle myosin heavy chain-IIA. This study was aimed to identify Korean GPS patients define clinical findings molecular characteristics on them. Methods: After taking family history, platelets were counted using hematologic autoanalyzer peripheral blood smear (PBS) examined for size...
Objectives: This study aimed to compare the demographic characteristics, responses negative emotions, and difficulties in emotion regulation between self-harming adolescents control individuals aged 12-14 years from community.Methods: Data were collected Chungcheong Province, South Korea, September 2021 November 2022.Demographic characteristics Depressed Mood Questionnaire Difficulties Emotion Regulation Scale-16 (DERS-16) compared self-harm groups.Results: The group exhibited a higher...
Portal, mesenteric, or splenic vein thrombosis is a very uncommon complication with significant mortality in the patients undergoing splenectomy for hematologic disorders. We report 49-year-old woman who developed portal, superior and thromboses after splenectomy. Four years before event, she presented marked thrombocytosis was diagnosed to have chronic myeloid leukemia variant thrombocythemic onset as evidence by Philadelphia (Ph1) chromosome b3a2 BCR/ABL transcript. Six weeks splenectomy,...
While T-cell non-Hodgkin's lymphoma (NHL) associated with hemophagocytic syndrome (HPS) has been frequently observed, B-cell NHL HPS rarely reported. We report a case of hepatosplenic in 41-year-old woman who presented fever unknown origin. An abdominal CT scan revealed splenomegaly focal splenic infarction. Splenectomy and liver wedge biopsy showed sinusoidal-pattern infiltration medium to large tumor cells positive reaction B-lymphocyte marker. Findings on bone marrow examination...
We investigated the effect and outcome of allogeneic peripheral blood stem cell (PBSC) rescue for aplastic anemia (AA) patients with graft failure after bone marrow transplantation (BMT). Seven (28%) 25 AA who received BMT from HLA-identical sibling donors developed late at a median 7 months (range, 2.0-9.3 months) transplantation. The were treated PBSC collected original donor mobilization granulocyte-colony stimulating factor (G-CSF). boost dose mononuclear cells was 3.1 x 10(8)/kg...
To compare the clonogenicity and distribution of CD34+ subsets in bone marrow (BM), granulocyte colony-stimulating factor (G-CSF) mobilized peripheral blood (PB) cord (CB), we analyzed vitro colony formation cells co-expressing differentiation molecules (CD38, HLA-DR), myeloid associated (CD13, CD33), a T-cell molecule (CD3), B-cell (CD19) from mononuclear (MNCs) three compartments. The proportions CD34+CD38- (BM: 4.4+/-2.8%, PB: 5.3+/-2.1%, CB: 5.9+/-3.9%) CD34+HLA-DR 4.7+/-3.4%,...
HWANG, SUNGJOO “TOMMY” MD*; KIM, HYOJIN MD†; LEE, WEON JU DO WON JUNG CHUL MD‡; KOOK, HOON MD§; JE MD∥ Author Information