A5100410665- Multiple Myeloma Research and Treatments
- Acute Myeloid Leukemia Research
- Cancer Treatment and Pharmacology
- Lymphoma Diagnosis and Treatment
- Protein Degradation and Inhibitors
- Chronic Lymphocytic Leukemia Research
- Hematopoietic Stem Cell Transplantation
- Acute Lymphoblastic Leukemia research
- Chronic Myeloid Leukemia Treatments
- Peptidase Inhibition and Analysis
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Cancer Mechanisms and Therapy
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Venous Thromboembolism Diagnosis and Management
- Immune Cell Function and Interaction
- CNS Lymphoma Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Retinoids in leukemia and cellular processes
- Colorectal Cancer Treatments and Studies
- CAR-T cell therapy research
- Lung Cancer Treatments and Mutations
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cancer therapeutics and mechanisms
- Viral-associated cancers and disorders
- Cutaneous lymphoproliferative disorders research
Dong-A University
2016-2025
Kim's Eye Hospital
2025
Chonnam National University Hwasun Hospital
2024
Dong-A University Hospital
2017-2023
EVERSANA (Canada)
2023
Ascension Providence Hospital
2023
Kyungpook National University Hospital
2023
Kyungpook National University
2023
Palmetto Hematology Oncology
2021
Yonsei University
2016
Abstract Background Several inflammatory response materials could be used for prediction of prognosis cancer patients. The neutrophil lymphocyte ratio (NLR), and the platelet (PLR) have been introduced prognostic scoring system in various cancers. objective this study was to determine whether NLR or PLR would predict clinical outcomes advanced gastric patients treated with oxaliplatin/ 5-fluorouracil (FOLFOX). Methods population consisted 174 Patients were 85 mg/m 2 oxaliplatin as a 2-h...
Abnormal hemostasis in cancer patients has prev iously been studied. The primary objective of the present study was to evaluate association between preoperative markers and clinicopathological parameters, identify a marker affecting survival following curative resection for colorectal cancer. A total 170 who underwent surgery carcinoma were evaluated. Preoperative coagulation tests included platelet, prothrombin time (PT), activated partial thromboplastin (aPTT), fibrinogen, D-dimer...
Unprovoked venous thromboembolism (VTE) is related to a higher incidence of occult cancer. D-dimer clinically used for screening VTE, and has often been shown be present in patients with malignancy. We explored the predictive value detecting cancer unprovoked VTE.We retrospectively examined data from 824 diagnosed deep vein thrombosis or pulmonary thromboembolism. Of these, 169 (20.5%) VTE were selected participate this study. was categorized into three groups as: <2,000, 2,000-4,000, >4,000...
To evaluate the outcomes and predictive factors for fluid resolution following three loading injections of faricimab neovascular age-related macular degeneration(AMD). This retrospective study included patients diagnosed with treatment-naïve AMD who received monthly faricimab. Changes in best-corrected visual acuity(BCVA) central retinal thickness(CRT) treatment were evaluated. The subretinal fluid(SRF), intraretinal fluid(IRF), serous pigment epithelial detachment(PED) was also assessed. In...
In the Republic of Korea, only lenalidomide, bortezomib, ixazomib, and thalidomide monotherapy are available as maintenance therapy post-autologous stem cell transplantation (ASCT). To determine whether confers a survival benefit in real world, we compared treatment outcomes according to use type patients who underwent ASCT following frontline with triplet regimen thalidomide, dexamethasone for newly diagnosed multiple myeloma 15 nationwide centers. A total 512 were analyzed (no-maintenance...
Adenomyoepithelioma (AME) of the breast is an uncommon tumor characterized by its dual differentiation into luminal cells and myoepithelial cells. In most cases these tumors have a benign clinical course, but distant metastases been reported. We present case 51-year-old woman diagnosed with malignant AME. The patient underwent right modified radical mastectomy, pathological examination confirmed diagnosis Ten months after operation, multiple hepatic, pleural, abdominal wall were detected. A...
Background/Aims To determine the efficacy and toxicity of docetaxel as a third-line therapy for patients with relapsed gastric cancer who have undergone modified oxaliplatin-fluorouracil (m-FOLFOX)-4 irinotecan-fluorouracil (m-FOLFIRI) regimens. Methods We analyzed 33 had been histologically diagnosed adenocarcinoma stomach progressed after m-FOLFOX-4 m-FOLFIRI Patients were treated cycles 75 mg/m2 on day 1 every 3 weeks. Results The median age was 56.0 years (range, 31.0 to 74.0), 73%...
Peritoneal carcinomatosis (PC) of colorectal cancer (CRC) is common and the second most cause death. Clinical studies regarding chemotherapy for CRC with PC have been classically rather limited in scope. We evaluated efficacy modified oxaliplatin, leucovorin, fluorouracil (m-FOLFOX4) regimen origin.CRC patients were treated cycles oxaliplatin at 85 mg/m(2) on day 1, leucovorin 20 followed by 5-fluorouracil (5-FU) via a 400 bolus 22 hours continuous infusion 600 5-FU days 1-2 2-week...
This study aimed to identify the benefits of autologous-stem cell transplantation (auto-SCT) and allogeneic-SCT (allo-SCT) in patients with aggressive T-cell lymphomas aid selection type clinical practice. retrospectively analyzed data from 598 who underwent for 2010 2020. In total, 317 up-front SCT as consolidation therapy. The 3-year progression-free survival (PFS) overall (OS) were 68.7% 76.1%, respectively. Patients auto-SCT had significantly better OS (p = 0.026) than those allo-SCT;...
Background A combination of busulfan (Bu) and cyclophosphamide (Cy) has been used as a standard myeloablative regimen for allogeneic hematopoietic stem cell transplantation (HSCT). Recent studies postulate that fludarabine (Flu) is less toxic substitute Cy. Methods Forty-two patients who were diagnosed with acute leukemia or myelodysplastic syndrome received BuFlu (n=17) BuCy (n=25) from August, 1999 to July, 2009 at Dong-A University Medical Center retrospectively analyzed. Results The...
Carfilzomib, lenalidomide, and dexamethasone (KRd) combination therapy improves the survival of patients with relapsed and/or refractory multiple myeloma (RRMM). Nonetheless, evidence on use KRd in Asian populations remains scarce. Accordingly, this study aimed to investigate regimen's efficacy a large group patients. This retrospective included RRMM who were treated at 21 centers between February 2018 October 2020. Overall, 364 (median age, 63 years). The overall response rate was 90%...
CD11c is a dendritic cell marker in humans, which potentially induces cytotoxic effect on lymphoma cells. Forkhead boxP3 (FOXP3) regulator of T lymphocyte the microenvironment lymphoma. The principal objective this study was to determine whether tumors' expressions and FOXP3 are predictive clinical outcomes diffuse large B-cell (DLBCL) patients receiving treatment with rituximab, cyclophosphamide, anthracycline, vincristine, prednisone (R-CHOP) combination chemotherapy. population consisted...
The International Myeloma Working Group has recently revised the diagnostic criteria for primary plasma cell leukemia (PCL) to circulating cells (CPCs) ≥ 5% in a peripheral blood smear. present study validated new patients with multiple myeloma or PCL diagnosed using previous criteria, who were administered immunomodulatory drugs proteasome inhibitors as induction therapy. We analyzed medical records of 1357 from eight hospitals South Korea. median age all was 64 years, and 187 (13.8%) had...
Myelodysplastic syndrome (MDS) is a preleukemic condition that transforms into acute myeloid leukemia. However, the genetic events underlying this transformation remain poorly understood. Aberrant DNA methylation may play causative role in disease and its prognosis. Thus, we compared profiles refractory anemia with excess blast (RAEB) to those cytopenia multilineage dysplasia (RCMD).Bone marrow samples were collected from 20 patients primary MDS (9 RAEB 11 RCMD), peripheral blood 4 healthy...
660 Background: Oxaliplatin- and irinotecan-based combination chemotherapy with infusional 5-FU leucovorin are currently the standard therapies for metastatic colorectal cancer. The objectives of this study were to evaluate efficacy capecitabine monotherapy as third line therapy cancer after failure containing oxaliplatin irinotecan, determine whether neutrophil-lymphocyte ratio (NLR), or platelet-lymphocyte (PLR) significant prognostic marker in Methods: We analyzed 60 patients who received...