A5019554969- MicroRNA in disease regulation
- Reproductive Biology and Fertility
- Reproductive Physiology in Livestock
- Reproductive System and Pregnancy
- Circular RNAs in diseases
- Clostridium difficile and Clostridium perfringens research
- Growth Hormone and Insulin-like Growth Factors
- Genetic and phenotypic traits in livestock
- Cancer-related molecular mechanisms research
- Endometriosis Research and Treatment
- Inflammasome and immune disorders
- Free Radicals and Antioxidants
- Machine Learning in Bioinformatics
- Mesenchymal stem cell research
- Salmonella and Campylobacter epidemiology
- Aquaculture disease management and microbiota
- Identification and Quantification in Food
- Yersinia bacterium, plague, ectoparasites research
- Circadian rhythm and melatonin
- Animal Genetics and Reproduction
- PARP inhibition in cancer therapy
- Antioxidant Activity and Oxidative Stress
- Cancer Immunotherapy and Biomarkers
University of Duhok
2018-2024
University of Baghdad
2024
Roslin Institute
2014-2022
University of Edinburgh
2016-2022
Salahaddin University-Erbil
2021
Several different miRNAs have been proposed to regulate ovarian follicle function; however, very limited information exists on the spatiotemporal patterns of miRNA expression during development. The objective this study was identify, using microarray, profiles associated with growth and regression dominant-size follicles in bovine monovular ovary characterize their distribution were collected from abattoir ovaries classified as small (4-8 mm) or large (12-17 mm); latter further healthy...
Abstract Context: Inadequate progesterone production from the corpus luteum is associated with pregnancy loss. Data available in model species suggest important roles of microRNAs (miRNAs) luteal development and maintenance. Objective: To comprehensively investigate involvement miRNAs during ovarian follicle-luteal transition. Design: The effects specific on survival steroid by human luteinized granulosa cells (hLGCs) were tested using miRNA inhibitors. Candidate identified through...
In a previous microarray study, we identified subset of micro RNAS (miRNAs), which expression was distinctly higher in atretic than healthy follicles cattle. the present investigated involvement those miRNAs granulosa and theca cells during atresia. Reverse Transcription-quantitative Polymerase Chain Reaction (RT-qPCR) confirmed that miR-21-5p/-3p, miR-150, miR-409a, miR-142-5p, miR-378, miR-222, miR-155, miR-199a-5p were expressed at levels (9-17 mm, classified based on steroidogenic...
Salmonella is a serious cause of the health issues in human and animal worldwide. has been isolated from different biological samples it considers as key role induction inflammation gastrointestinal tract which turn diarrhoea species. To further understand involvement contaminating infecting fresh eggs meat free-range chicken. This study aimed to establish microbiological molecular detections cloaca chicken identify predicted functions using Kyoto Encyclopedia Gene Genomic (KEGG) pathways...
Introduction: The present study aimed to determine the alterations in serum levels of tumor markers used evaluate cardiac, renal and liver function, detect interleukin (IL)-18 rs1946518 polymorphism breast (BC), colorectal (CRC) prostate cancer (PCa) patients. Methods: Blood samples were collected from 65 female BC, 116 CRC, 79 PCa 88 myocardial infarction (MI) patients, 110 healthy individuals concentration cardiac markers. Furthermore, IL-18 was assessed using amplification refractory...
C lostridium perfringens is a zoonotic pathogen causing various health problems like gas gangrene, food poisoning, and other enteric infections, especially in domestic livestock, leading to significant global economic losses.In present study, C. strains were isolated identified depending on 16 rRNA genotyping based genes encoding alpha, beta, epsilon, iota, enterotoxin, NetB toxins, then sequencing of 16S some main toxin-producing 219 samples collected from domesticated ruminants sheep,...
Bull fertility is pivotal to the prosperity of cattle industry worldwide. miR-202 has been shown be gonad specific and have key roles in function different species. To further understand involvement bull reproduction, this study aimed establish its localization bovine testicular tissue identify putative biological functions using bioinformatics approaches. We assessed expression paraffin-embedded samples collected form an abattoir situ hybridization. was present Sertoli cells germ at stages...
lostridium perfringens is a zoonotic pathogen causing health problems like gas gangrene, food poisoning, and other enteric infections, especially in livestock, global economic losses.In the present article, C. isolates were obtained from 94 samples, including chicken shawerma, meat kabab, kabab; canned fish chickens collected 6 markets stores, 34 restaurants within Duhok province, Iraq during period June 1 st , to August 31, 2022.The strains isolated on CHROMagar TM agar blood agar,...
Background: Micro RNA155 (miR-155) was identified as an essential determinant in immunological responses, and its genetic variants have increasing attention due to their ability modulate expression potentially influence the susceptibility autoimmune illnesses including rheumatoid arthritis, systemic sclerosis, lupus erythematosus, etc.Objectives: To examine impact of miR-155 gene polymorphism (rs767649A>T) association with multiple sclerosis (MS) a sample Iraqi patients.Materials Methods: A...
Ovarian cancer (OC) is one of the top global reasons death among women with high prevalence. can be categorized into epithelial, non-epithelial, and metastatic types. Animal models such as mice are intensively utilized to investigate molecular mechanism controlling development in human beings. Recently, several approaches have been extremely studied control ovarian at transcriptional or post-transcriptional levels using small RNAs molecules including microRNAs. These played a key role growth...
Our previous studies showed that the miRNA clusters, miR-183-96-182 and miR-212-132, may be critical in promoting luteal cell survival progesterone production both bovine humans. To further understand their involvement development, this study aimed to establish expression of these miRNAs different types, namely, endothelial steroidogenic, isolated using fluorescence-activated sorting (FACS). We each two populations based on presence endothelia surface marker, CD144, uptake lipophilic dye,...
Searchable abstracts of presentations at key conferences on reproductive biology and medicine ISSN 2052-1472 (online)
Melatonin, a hormone secreted by the pineal gland, is known to have anti-mutagenic, antioxidant and oncostatic functions. This beneficial action of melatonin has been explained in terms its ability scavenge free radicals activities anti-oxidant enzymes. The present study was carried out evaluate anti-tumor activity on two stage process skin carcinogenesis, A significant reduction tumor incidence, burden, yield, cumulative number papilloma observed mice treated with 10mg/kg as compared...
Reproductive inefficiency in sheep is a critical source of reduction small ruminant profitability worldwide. The importance insulin-like growth factors1 and 2 belonging to the factors system were identified as pivotal key roles ovarian follicular development steroidogenesis different species. This study aimed detect IGF-1 IGF-2 genes Oestrogen levels ovine large antral follicles collected from an abattoir using conventional PCR ELISA, respectively, well investigate relationships between IGFs...
Reproductive inefficiency in sheep is a critical source of reduction small ruminant profitability worldwide. The importance insulin-like growth factors1 and 2 belonging to the factors system were identified as pivotal key roles ovarian follicular development steroidogenesis different species. This study aimed detect IGF-1 IGF-2 genes Oestrogen levels ovine large antral follicles collected from an abattoir using conventional PCR ELISA, respectively, well investigate relationships between IGFs...