- Child Nutrition and Water Access
- Global Maternal and Child Health
- Extracellular vesicles in disease
- Cell Adhesion Molecules Research
- Global Health Care Issues
- Climate Change and Health Impacts
- Food Security and Health in Diverse Populations
- MicroRNA in disease regulation
- Iron Metabolism and Disorders
- Healthcare cost, quality, practices
- Health disparities and outcomes
- Dialysis and Renal Disease Management
- Global Cancer Incidence and Screening
- Complement system in diseases
- Energy and Environment Impacts
- Demographic Trends and Gender Preferences
- Healthcare Systems and Reforms
- Cancer Immunotherapy and Biomarkers
- Breastfeeding Practices and Influences
- Insurance, Mortality, Demography, Risk Management
- Pregnancy and preeclampsia studies
- Nutritional Studies and Diet
- PARP inhibition in cancer therapy
- Reproductive System and Pregnancy
- Public Health and Nutrition
Salahaddin University-Erbil
2009-2024
Karolinska Institutet
2018-2024
Institute for Health Metrics and Evaluation
2020-2023
University College London
2021
University of Washington
2020
Mario Negri Institute for Pharmacological Research
2020
Istituti di Ricovero e Cura a Carattere Scientifico
2020
Sapienza University of Rome
2020
Center For Reconstructive Urethral Surgery
2020
Bangladesh University of Health Sciences
2020
Abstract Extracellular vesicles (EVs) play a key role in many physiological and pathophysiological processes hold great potential for therapeutic diagnostic use. Despite significant advances within the last decade, issue of EV storage stability remains unresolved under investigated. Here, we aimed to identify conditions stabilizing EVs comprehensively compared impact various buffer formulations at different temperatures on derived from cellular sources up 2 years. features including...
Extracellular vesicles (EVs) can be harvested from cell culture supernatants and all body fluids. EVs conceptually classified based on their size biogenesis as exosomes microvesicles. Nowadays, it is however commonly accepted in the field that there a much higher degree of heterogeneity within these two subgroups than previously thought. For instance, surface marker profile likely dependent source, cell's activation status, multiple other parameters. Within recent years, several new methods...
There are limited published data regarding the recent incidence trends of cancer in Iraqi Kurdistan.The present study assessed epidemiological estimates incidence, as well providing a projection future upcoming decade by analysing population-based registry between 2013 and 2019, both Erbil Duhok governorates. A retrospective analysis was performed on retrieved from Medical Statistics Department at Ministry Health, Kurdistan Regional Government (KRG).The total number female patients higher...
Abstract Haematopoiesis dysregulation with the presence of immature myeloid and erythroid immunosuppressive cells are key characteristics immune escape phase tumour development. Here, role in vitro generated B16F10 cell‐derived extracellular vesicles (tEVs) as indirect cellular communicators, participating tumour‐induced haematopoiesis, was explored. The isolated tEVs displayed features small EVs a size range 100–200 nm, expressed common EV markers CD63, CD9, Alix, had spherical shape lipid...
Introduction: The present study aimed to determine the alterations in serum levels of tumor markers used evaluate cardiac, renal and liver function, detect interleukin (IL)-18 rs1946518 polymorphism breast (BC), colorectal (CRC) prostate cancer (PCa) patients. Methods: Blood samples were collected from 65 female BC, 116 CRC, 79 PCa 88 myocardial infarction (MI) patients, 110 healthy individuals concentration cardiac markers. Furthermore, IL-18 was assessed using amplification refractory...
Abstract There is limited published data on recent cancer incidence trends in Iraqi Kurdistan. Therefore, this study assesses epidemiological estimates of as well the projection future upcoming decade by analysing population-based registry from 2013 to 2019 both Erbil and Duhok governorates. A retrospective was conducted retrieved Medical Statistics Department at Ministry Health, KRG. The total number female patients higher governorates, more than doubled Duhok, 73 174 patients/100,000...
Abstract Extracellular vesicles (EVs) have recently emerged as a highly promising cell-free bio-therapeutics. While range of engineering strategies been developed to functionalize the EV surface, current approaches fail address limitations associated with endogenous surface display, pertaining heterogeneous display commonly used EV-loading moieties among different subpopulations. Here we present novel platform multiple protein therapeutics simultaneously on surface. As proof-of-concept,...
Background and objective: The purpose of the present study was to determine effects hemodialysis peritoneal dialysis on some hematological biochemical parameters in patients with renal failure dialysis. Methods: Fifty two were taken this experiment studied kidney disease center hawler teaching hospital, twenty six for haemodialysis remaining process. Some before after Results: In Hemodialysis Patients: Hemoglobin concentration (Hb gm/dl), Red blood cells (RBCs x106/μl) packed cell volume...
ABSTRACT Signaling via inhibitory KIR/Ly49 receptors preserves natural killer (NK) cell self-tolerance but also conveys NK reactivity towards MHC class-I low target cells in an education process. Here, we demonstrate that mouse by H-2D d regulates transcription of several genes Ly49A+ including Ptpn6 , encoding the phosphatase SHP-1. SHP-1 was highly expressed uneducated cells, which knock-out increased responsiveness. Following NKp46 triggering a higher synaptic abundance phosphorylated...