A5050559922- Infant Nutrition and Health
- Breastfeeding Practices and Influences
- Neonatal Respiratory Health Research
- Diet and metabolism studies
- Gastrointestinal motility and disorders
- Clinical Nutrition and Gastroenterology
- Advanced Chemical Sensor Technologies
- Gut microbiota and health
- Insect and Pesticide Research
- Child Nutrition and Feeding Issues
- Nutritional Studies and Diet
- Pesticide Residue Analysis and Safety
- Postharvest Quality and Shelf Life Management
- Metabolomics and Mass Spectrometry Studies
- Sulfur Compounds in Biology
- Sensory Analysis and Statistical Methods
- Diet, Metabolism, and Disease
- Obesity, Physical Activity, Diet
- Escherichia coli research studies
- Intestinal and Peritoneal Adhesions
- Vibrio bacteria research studies
- Microscopic Colitis
- Helicobacter pylori-related gastroenterology studies
- Congenital Anomalies and Fetal Surgery
- Viral gastroenteritis research and epidemiology
Gastroenterology Hospital "Saverio de Bellis"
2024-2025
Cereal Research Centre
2023-2024
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2016-2023
Centro di Ricerca per l’Orticoltura
2023
University of Milan
2016-2020
Fortifying human milk contributes to the prevention of postnatal growth failure in preterm infants. Because natural variability milk, targeted fortification has been advocated. However, data regarding efficacy and safety prolonged are scarce. We aimed assess infants compared with standard fortification, as well effects on infant growth. conducted an interventional study during hospital stay healthy very low birth weight who were exclusively fed milk. Pools collected for 24 h analysed using...
Donor human milk (DHM) is the best alternative for preterm infants when their own mother's unavailable. DHM should be pasteurized to guarantee microbiological safety; however, this process can influence macronutrient content. The aim of study was investigate effect Holder pasteurization (HoP) on
Irritable Bowel Syndrome (IBS) is a complex gastrointestinal disorder characterized by chronic abdominal pain and altered bowel habits, often linked to disruptions in intestinal barrier function. Increased permeability plays key role IBS pathogenesis, affecting immune responses, gut microbiota, inflammation. This study conducts bibliometric analysis explore global research trends on IBS, focusing contributors, collaboration networks, thematic shifts, particularly the interplay between...
Hydrogen sulfide (H2S) is a critical gasotransmitter that plays dual role in physiological and pathological processes, particularly the gastrointestinal tract. While levels of H2S exert cytoprotective effects, excessive concentrations can lead to toxicity, oxidative stress, inflammation. The aim this study was investigate dose-dependent effects exogenous on mitochondrial functions biogenesis intestinal epithelial cells under non-stressed conditions. Using Caco-2 monolayer model, we evaluated...
Background: Patients with irritable bowel syndrome (IBS) often experience comorbid psychological conditions, notably depression and anxiety. Evidence suggests that these conditions are linked to gut barrier dysfunction, dysbiosis, chronic inflammation. All factors central IBS pathophysiology mood disturbances. Polyunsaturated fatty acids (PUFAs) play crucial roles in modulating inflammation depression. This study examined the associations among intestinal permeability, PUFA profiles,...
Many patients with irritable bowel syndrome (IBS) have a compromised intestinal barrier associated low-grade inflammation. Polyunsaturated fatty acids (PUFAs) are potential mediators of inflammation: omega-6 PUFAs pro-inflammatory, while omega-3 antioxidant and anti-inflammatory. Zonulin is biomarker for small permeability (s-IP). This study investigated the relationship between gastrointestinal (GI) integrity in IBS predominant diarrhea (IBS-D). We evaluated GI function indicators urine...
Introduction: Human milk is the optimal nutrition for preterm infants. When mother's own unavailable, donor human recommended as an alternative The association among early nutrition, body composition and future risk of disease has recently attracted much interest. aim this study was to investigate effect on Materials Methods: Very low birth weight infants (VLBW: <1,500 g) with a gestational age (GA) between 26 34 weeks were included. Clinical data, anthropometric measurements nutritional...
Human milk is a vehicle for bioactive compounds and beneficial bacteria which promote the establishment of healthy gut microbiome newborns, especially preterm infants. Pasteurized donor human (PDHM) second-best option when mother's own unavailable. Since pasteurization affect microbiological quality milk, PDHM was inoculated with different samples then incubated, in order to evaluate effect terms bacterial growth, proteolytic phenomena.In an in-vitro study at 10% v/v using ten samples....
Among breastfeeding determinants, the marketing of breast milk substitutes might contribute to suboptimal rates. The aim this study was investigate effect receiving information on We conducted a randomized, single-blind, controlled trial from 2012 2014 in northern Italian maternity ward. enrolled 802 Caucasian mothers who gave birth healthy, full-term singletons with weight > 2500 g and were exclusively delivery discharge. Mothers infants congenital diseases, chromosomal abnormalities,...
Background: Donor human milk (DHM) is the recommended feeding for preterm infants when mother's own unavailable or insufficient. DHM macronutrient's variability may have significant implications on growth. Different pooling strategies could be used to improve macronutrient content, facilitating achievement of nutritional requirements preterm. Objective: The aim was compare impact random (RP) and target (TP) content identify which RP practice allows a composition as similar possible that...
A paucity of evidence is available regarding the impact diet's quality during pregnancy and lactation on body composition breast-feeding mothers. The purpose present study was to evaluate association between maternal degree adherence Mediterranean diet (MD) measures specifically those relating fat, in period. cross-sectional healthy mothers full-term babies has been conducted. At 30 ± 10 d after delivery, anthropometric measurements were assessed. food frequency questionnaire performed...
The nutritional management of preterm infants is a critical point care, especially because the increased risk developing extrauterine growth restriction (EUGR), which associated with worsened health outcomes. Energy requirements in are simply estimated, so measurement resting energy expenditure (REE) should be key evaluation infants. Although predictive formulae available, it well known that they imprecise. aim our study was REE and protein oxidation (Ox) very low birth weight (VLBWI)...
Nowadays, different systems for reducing pesticides in table grapes are being tested at production stages either the field or postharvest. The present study ozonated water treatments beginning of cold storage Princess® seedless grape variety to reduce residue contents some and evaluate their effect on gray mold berry microbiome. An ozone generator capable producing an concentration ranging from 18 65 Nm3 was utilized obtaining three levels water: 3, 5 10 mg/L. Ozonated placed a 70 L plastic...
During cold storage, grapes undergo changes that affect their visual, mechanical, and organoleptic properties, potentially impacting quality negatively influencing consumer acceptance. Key parameters include uniform color, crunchiness, flesh consistency. We evaluated the influence of two distinct packaging methods on chromatic characteristics, hardness, pedicel detachment resistance fourteen new seedless white red grape varieties during storage. These factors are crucial for maintaining...
Irritable bowel syndrome with diarrhea (IBS-D) is the most prevalent subtype of IBS, characterized by chronic gastrointestinal symptoms in absence identifiable pathological findings. This study aims to investigate molecular mechanisms underlying IBS-D using transcriptomic data. By employing causal network inference methods, we identify key modules associated IBS-D. Utilizing data from public databases and applying advanced computational techniques, uncover potential biomarkers therapeutic...
Irritable bowel syndrome (IBS) and obesity are associated with intestinal barrier alterations that result in low-grade inflammation. Zonulin fatty acid-binding protein (I-FABP) assess gut health, while urinary indican concentrations reflect dysbiosis the small intestine. Physical activity, such as Fitwalking, aids weight management improves permeability. This study assesses impact of a 12-week Fitwalking program on health IBS patients categorized by body mass index (BMI).
Aims: This study explores the link between body mass index (BMI), intestinal permeability, and associated changes in anthropometric impedance parameters, lipid profiles, inflammatory markers, fecal metabolites, gut microbiota taxa composition participants having excessive mass. Methods: A cohort of 58 obese individuals with comparable diet, age, height was divided into three groups based on a priori clustering analyses that fit BMI class ranges: Group I (25–29.9), II (30–39.9), III (>40)....
ABSTRACT Objectives: The fortification of human milk can result in increased osmolality, which may be associated with adverse effects for preterm infants. To evaluate the effect target on osmolality and microbiological safety donor raw mature during first 72 hours storage. Methods: We performed 63 pasteurized (PDHM) 54 (RMM) samples a laminar flow hood. Osmolality (mOsm/kg) was evaluated before (T0), immediately after (T1), at 6 (T2), 24 (T3), 48 (T4), (T5) fortification. Microbiological...
Nowadays, different systems for reducing pesticides in table grapes are being tested at production stages either the field or post-harvest. The present study ozonated water treatments beginning of cold storage on Melissa seedless grape variety to reduce residue contents some pesticides. An ozone generator capable producing concentrations ranging from 18 65 Nm 3 was utilized obtaining three concentration levels water: 3, 5 and 10 mg/L. Ozonated placed into a 70 L plastic box where 500 g...
In this work, we present a procedure that combines the sensory analysis outcome and spectroscopic data collected in NIR region. This method allows for complete characterization of each sample before ingestion without any alteration its composition or appearance. spectra hundreds samples parameters evaluated have been collected. The were then analyzed by conventional analytical procedures, using texture analyzer, refractometer, an electric conductivity meter. Moreover, spectrum was recorded...