- Probiotics and Fermented Foods
- Protein Hydrolysis and Bioactive Peptides
- Proteins in Food Systems
- Infant Nutrition and Health
- Bacteriophages and microbial interactions
- Food composition and properties
- Gut microbiota and health
- Meat and Animal Product Quality
- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Microbial Metabolites in Food Biotechnology
- Food Allergy and Anaphylaxis Research
- Microbial Inactivation Methods
- Child Nutrition and Feeding Issues
- Breastfeeding Practices and Influences
- Horticultural and Viticultural Research
- Biochemical effects in animals
- Identification and Quantification in Food
- Fermentation and Sensory Analysis
- Bacterial Genetics and Biotechnology
- Phytochemicals and Antioxidant Activities
- Biochemical Analysis and Sensing Techniques
- Phytase and its Applications
- Milk Quality and Mastitis in Dairy Cows
- Animal Genetics and Reproduction
University of Milan
2016-2025
Ministerio de Defensa
2015
Mylan (Switzerland)
2015
Vilnius University
2007-2008
The ability to positively affect host health through the modulation of immune response is a feature increasing importance in measuring probiotic potential bacterial strain. However, identities cell components involved cross talk with cells remain elusive. In this study, we characterized dairy strain Lactobacillus helveticus MIMLh5 and its surface-layer protein (SlpA) using vitro ex vivo analyses. We found that SlpA exert anti-inflammatory effects by reducing activation NF-κB on intestinal...
ABSTRACT The research described here was aimed at the selection of oral bacteria that displayed properties compatible with their potential use as probiotics for pharyngeal mucosa. We included in study 56 newly isolated from pharynges healthy donors, which were identified intraspecies level and characterized vitro probiotic potential. experiments led us to select two bacterial strains ( Streptococcus salivarius RS1 ST3) compare them prototype S. strain K12. All three efficiently bound FaDu...
Mass spectrometry has become the technique of choice for assessment a high variety molecules in complex food matrices. It is best suited monitoring evolution digestive processes vivo and vitro. However, considering equipment available different laboratories diversity sample preparation methods, instrumental settings data acquisition, statistical evaluations, interpretations results, it difficult to predict priori ideal parameters optimal results. The present work addressed this uncertainty...
Grana Padano (GP) is an Italian hard cooked cheese characterized by a long ripening process and high protein Ca contents. After in vitro static simulated gastrointestinal digestion, GP digest contained caseinophosphopeptides that were 6 to 24 amino acids length, including tri-phosphorylated species incorporating the pSer-pSer-pSer-Glu-Glu cluster. Using rat ileum tissue, was used assess absorption ex vivo, which showed significantly better results for comparison CaCO3 aqueous solution. An...
Melatonin is a neurohormone, chronobiotic, and antioxidant compound found in wine deriving directly from grapes and/or synthesized by yeast during alcoholic fermentation. In addition, melatonin isomer has been detected different foods, among them. The special interest for related to the fact that it was greater quantities than probably shares some of its biological properties. Despite this, chemical structure not yet defined; although researchers hypothesize, could be with ethylacetamide...
The probiotic approach represents an alternative strategy in the prevention and treatment of infectious diseases, not only at intestinal level but also other sites body where microbiota plays a role maintenance physiological homeostasis. In this context, we evaluated vitro potential abilities dairy bacteria controlling Streptococcus pyogenes infections pharyngeal level. Initially, analyzed bacterial adhesion to FaDu hypopharyngeal carcinoma cells ability antagonize S. on cell layers HaCat...
ABSTRACT Bifidobacteria are Gram-positive inhabitants of the human gastrointestinal tract that have evolved close interaction with their host and especially host's immune system. The molecular mechanisms underlying such interactions, however, largely unidentified. In this study, we investigated immunomodulatory potential Bifidobacterium bifidum MIMBb75, a bacterium intestinal origin commercially used as probiotic. Particularly, focused our attention on TgaA, protein expressed outer surface...