A5012599916- Malaria Research and Control
- Mosquito-borne diseases and control
- Drug-Induced Hepatotoxicity and Protection
- Global Maternal and Child Health
- Computational Drug Discovery Methods
- Parasites and Host Interactions
- Global Health and Surgery
- Trauma and Emergency Care Studies
- Child Nutrition and Water Access
- Antibiotic Use and Resistance
- Phytoestrogen effects and research
- Injury Epidemiology and Prevention
- Antibiotics Pharmacokinetics and Efficacy
- Neonatal and Maternal Infections
- Venomous Animal Envenomation and Studies
- Zoonotic diseases and public health
- Animal Disease Management and Epidemiology
- Food and Agricultural Sciences
- Clinical Laboratory Practices and Quality Control
- Infant Development and Preterm Care
- Inhalation and Respiratory Drug Delivery
- Viral Infections and Vectors
- Digital Imaging for Blood Diseases
- Trypanosoma species research and implications
- Herpesvirus Infections and Treatments
Addis Ababa University
2022-2024
International Trachoma Initiative
2021-2023
U.S. President's Malaria Initiative
2023
Haramaya University
2012-2017
Columbia University
2010
Jimma University
2001
Anopheles stephensi, an Asian malaria vector, continues to expand across Africa. The vector is now firmly established in urban settings the Horn of Its presence areas where resurged suggested a possible role causing outbreaks. Here, using prospective case-control design, we investigated An. stephensi transmission following outbreak Dire Dawa, Ethiopia April-July 2022. Screening contacts patients with and febrile controls revealed spatial clustering Plasmodium falciparum infections around...
Recent efforts in malaria control have resulted great gains reducing the burden of Plasmodium falciparum, but P. vivax has been more refractory. Its ability to form dormant liver stages confounds and elimination efforts. To compare efficacy safety primaquine regimens for radical cure, we undertook a randomized controlled trial Ethiopia.Patients with normal glucose-6-phosphate dehydrogenase status symptomatic mono-infection were enrolled randomly assigned receive either chloroquine (CQ) or...
Background: The surgical field in Africa has long grappled with a gender imbalance, women being significantly underrepresented. Despite global efforts to foster diversity healthcare practices, African pursuing careers still face substantial hurdles. This paper investigates these women’s experiences and challenges, aiming raise awareness of issues propose strategies for improving equity. Objective: To describe contextual aspects barriers affecting surgery Africa. Methods: A cross-sectional...
Objectives and methods Quality laboratory services are a requisite to guide rational case management of malaria. Using pre-tested, standardized assessment tool, we assessed diagnostic capacity in 69 primary, secondary tertiary health facilities as well specialized laboratories five administrative zones Oromia Regional State, Ethiopia, during February March 2009. Results There was marked variability among the assessed. Of surveyed, 53 provided both comprehensive malaria diagnosis outpatient...
The Enhancing Nutrition and Antenatal Infection Treatment (ENAT) intervention was implemented in Ethiopia to improve newborn birth weight (BW) by strengthening the contents quality of antenatal care (ANC), especially point-of-care testing for maternal infections. This study examined effect ENAT on weight.We conducted a cluster randomized controlled trial 22 clusters (health centers), equally between 11 control clusters. enrolled followed pregnant women from ANC booking end pregnancy or loss...
Background: Antimicrobials are among the most frequently prescribed medications for pediatric patients. However, inappropriate use of them can increase morbidity, mortality, healthcare costs, and largely antimicrobial resistance. This study aims to assess utilization pattern in ward Hiwot Fana Specialized University Hospital. Methods: Retrospective cross-sectional was conducted utilization. In this study, 403 medical records selected by systematic random sampling were reviewed. Data...
Background: Access to information through continuing education (CE), reference and other resource materials is a prerequisite the achievement of MDGs. health workers in Ethiopia has been poor will be further challenged by deployment 30,000 Health Extension Workers (HEW). Therefore, study was undertaken make clear needs assessment, define priorities identify resources plan appropriate CE programs prepare materials. Method: The conducted 27 woredas, 50 posts (HP) on 60 HEW all regions where...
A survey qualitative was conducted to assess the awareness on food borne zoonosis and its relation with Veterinary Public Health Services in Addis Ababa surrounding districts from November 2008 May 2009. Structured questionnaire used study. Questionnaires were distributed 384 individuals, of which 196 elementary high school students, Graduates. Factors like education level, information source profession considered for possible explanation results. The use inspected animal products is found...
Malaria and HIV/AIDS constitute major public health problems in Ethiopia, but the burden associated with malaria-HIV co-infection has not been well documented. In this study, of malaria among HIV positive negative adult outpatients attending facilities Oromia National Regional State, Ethiopia was investigated.A comparative cross-sectional study HIV-positive patients having routine follow-up visits at care treatment clinics HIV-seronegative general medical outpatient departments 12 during...
Plasmodium falciparum and vivax are co-endemic in Ethiopia. This study investigated whether mixed infections were missed by microscopy from a 2017 therapeutic efficacy at two health facilities All patients (N = 304) initially classified as having single-species P. (n 148 samples) or 156). Dried blood spots tested for antigens bead-based multiplex assay pan-Plasmodium aldolase, lactate dehydrogenase, histidine-rich protein 2. Of 304 samples, 13 (4.3%) contained both analyzed polymerase chain...
Abstract Background Routine monitoring of anti-malarial drugs is recommended for early detection drug resistance and to inform national malaria treatment guidelines. In Ethiopia, the guidelines employ a species-specific approach. Artemether-lumefantrine (AL) chloroquine (CQ) are first-line schizonticidal treatments Plasmodium falciparum vivax , respectively. The National Malaria Control Elimination Programme in Ethiopia considering dihydroartemisinin-piperaquine (DHA/PPQ) as an alternative...
Abstract Anopheles stephensi , an Asian urban malaria vector, continues to expand across Africa. We investigated the role of An. in transmission following a dry season outbreak Dire Dawa, Ethiopia, from April July 2022, using prospective case control design. Plasmodium falciparum microscopy-positive febrile patients (n = 101) and microscopy-negative controls 189) were identified their contacts 662) screened. Spatial clustering P. infections detected but not which was strongly associated with...
Abstract Background Declining efficacy of chloroquine for the treatment Plasmodium vivax malaria has been reported in different endemic settings Ethiopia. This highlights need to assess alternative options P. with artemisinin-based combination therapy, such as pyronaridine-artesunate. regimen shown high uncomplicated both Africa and Asia. However, limited data are available from study was conducted safety pyronaridine-artesunate Northwest Methods A single arm prospective Hamusite area,...
Abstract Background Reactive and proactive case detection measures are widely implemented by national malaria elimination programs globally. Ethiopia decided to include Case Detection (RCD) targeted Mass Drug Administration (tMDA) approaches as part of their strategy along with rigorous evaluation. The purpose this study is compare the impact RCD tMDA on over 2-year period, looking at annual parasite incidence before after intervention. Methods will be conducted in East Hararghe zone...
Declining efficacy of chloroquine against Plasmodium vivax malaria has been documented in Ethiopia. Thus, there is a need to assess the alternative schizontocidal anti-malarials such as dihydroartemisinin-piperaquine (DHA-PPQ) P. malaria-infected patients. This study was conducted evaluate therapeutic DHA-PPQ drug South West Ethiopia.This single-arm, prospective patients with uncomplicated malaria. The from May 2021 August 2021, based on standard World Health Organization protocol for...
<title>Abstract</title> <bold>Background</bold>The Enhancing Nutrition and Antenatal Infection Treatment (ENAT) intervention was implemented in Ethiopia to improve newborn birth weight by strengthening the contents quality of antenatal care (ANC), especially point-of-care testing for maternal infections. This study examined effect ENAT on weight.<bold>Methods</bold>We conducted a cluster randomized controlled trial 22 clusters (health centers), equally between 11 control clusters. enrolled...