A5064008010- Mosquito-borne diseases and control
- Malaria Research and Control
- Insect Pest Control Strategies
- Parasites and Host Interactions
- Invertebrate Immune Response Mechanisms
- Viral Infections and Vectors
- Biosensors and Analytical Detection
- Studies on Chitinases and Chitosanases
- Insect Resistance and Genetics
- Digital Economy and Work Transformation
- Simulation Techniques and Applications
- Trypanosoma species research and implications
- International Law and Aviation
- Aquaculture disease management and microbiota
- Insect symbiosis and bacterial influences
- Travel-related health issues
- Insect Utilization and Effects
- Parasitic Diseases Research and Treatment
- Viral Infectious Diseases and Gene Expression in Insects
Division of Parasitic Diseases and Malaria
2021-2025
Centers for Disease Control and Prevention
2009-2025
The Centers
2021-2024
U.S. President's Malaria Initiative
2023
Goshen College
2019
Atlanta Research and Education Foundation
2009-2012
Anopheles stephensi, an Asian malaria vector, continues to expand across Africa. The vector is now firmly established in urban settings the Horn of Its presence areas where resurged suggested a possible role causing outbreaks. Here, using prospective case-control design, we investigated An. stephensi transmission following outbreak Dire Dawa, Ethiopia April-July 2022. Screening contacts patients with and febrile controls revealed spatial clustering Plasmodium falciparum infections around...
Eight cases of locally acquired, mosquito-transmitted (i.e., autochthonous) Plasmodium vivax malaria, which has not been reported in the United States since 2003, were to CDC from state health departments Florida and Texas during May 18-July 17, 2023. As August 4, 2023, case surveillance, mosquito surveillance control activities, public outreach education activities continue both states. U.S. clinicians need consider a malaria diagnosis patients with unexplained fever, especially areas where...
Hispaniola, which is shared by Haiti and the Dominican Republic, remains last island in Caribbean that still endemic for malaria, with bearing highest caseload. Few studies have examined ecology of malaria vectors Haiti. Five species Anopheles been described on island, but exophilic albimanus ( An. ) considered primary vector Households recruited a case–control study profiling risk factors symptomatic Plasmodium falciparum P. infections were approached to participate an entomological study....
Abstract Background In characterizing malaria epidemiology, measuring mosquito infectiousness informs the entomological inoculation rate, an important metric of transmission. PCR-based methods have been touted as more sensitive than current “gold-standard” circumsporozoite (CSP) ELISA. Wider application has limited by lack specificity for infectious sporozoite stage. We compared a PCR method detecting parasite’s mitochondrial (mt) cytochrome oxidase I ( COX-I ) gene with ELISA protein...
Abstract Background Malaria is a top cause of mortality on the island nation Madagascar, where many rural communities rely subsistence agriculture and livestock production. Understanding feeding behaviours Anopheles in this landscape crucial for optimizing malaria control prevention strategies. Previous studies southeastern Madagascar have shown that mosquitoes are more frequently captured within 50 m livestock. However, it remains unknown whether these preferentially feed Here, mosquito...
Abstract Anopheles stephensi , an Asian urban malaria vector, continues to expand across Africa. We investigated the role of An. in transmission following a dry season outbreak Dire Dawa, Ethiopia, from April July 2022, using prospective case control design. Plasmodium falciparum microscopy-positive febrile patients (n = 101) and microscopy-negative controls 189) were identified their contacts 662) screened. Spatial clustering P. infections detected but not which was strongly associated with...
Abstract Background When rearing morphologically indistinguishable laboratory strains concurrently, the threat of unintentional genetic contamination is constant. Avoidance accidental mixing difficult due to use common equipment, technician error, or possibility self relocation by adult mosquitoes ("free fliers"). In many cases, are distinguish because morphological and similarity, especially when colonies isolates certain traits from same parental strain, such as eye color mutants,...
Abstract Background Plasmodium spp. sporozoite rates in mosquitoes are used to better understand malaria transmission intensity, the relative importance of vector species and impact interventions. These typically estimated using an enzyme-linked immunosorbent assay (ELISA) utilizing antibodies against circumsporozoite protein falciparum, vivax VK210 ( P. 210) or VK247 247), employing assays that were developed over three decades ago. The ELISA method requires a separate plate for each...
Abstract Malaria is responsible for over 435,000 deaths annually, mostly occurring in sub-Saharan Africa. Detecting Plasmodium spp. sporozoites (spzs) the salivary glands of Anopheles (Diptera: Culicidae) vectors with circumsporozoite enzyme-linked immunosorbent assay (csELISA) an important surveillance method. However, current technological advances are intellectual property and often require distribution highly trained users. The transition into paper-based rapid plataforms would allow...
Abstract Triatomines (Hemiptera: Reduviidae) are hematophagous insects that transmit Trypanosoma cruzi, the etiological agent for Chagas disease, to humans and other mammals. As medically important vectors, species such as Rhodnius prolixus have long been used a model organism physiological studies. Laboratory rearing of triatomines is needed support vector parasite research. Many environmental conditions, suitable housing containers, light source duration, temperature, humidity, density,...
A case of locally acquired (autochthonous) mosquito-transmitted Plasmodium vivax malaria was diagnosed in Arkansas September 2023. This represents the 10th autochthonous identified nationally 2023, after 20 years without recorded local mosquitoborne transmission United States. The public health response included investigation, active surveillance, mosquito surveillance and control, assessment medical countermeasures, clinical outreach. Prompt diagnosis appropriate treatment can improve...
Adult mosquito size is constrained by conditions experienced in the larval stage including amount and quality of diet. The energy expended collecting diet depends partly on its concentration, water depth, species. In order to better understand these interactions, individual Anopheles gambiae s.s. Giles were cultured adult three types experiments which one following was fixed other two varied: volume, amount, concentration. addition survival, days development pupation wing length determined....
Abstract Background: Plasmodium spp. sporozoite rates in mosquitoes are used to better understand malaria transmission intensity, the relative importance of vector species and impact interventions. These typically estimated using an enzyme-linked immunosorbent assay (ELISA) utilizing antibodies against circumsporozoite protein P. falciparum (Pf), vivax VK210 (Pv210) or VK247 (Pv247), employing assays that were developed over three decades ago. The ELISA method requires a separate plate for...
<h3>Introduction</h3> Throughout Great Ormond Street Hospital, we have a skilled group of healthcare assistants who provide expert care to patients across all specialities. The Shape Caring Review (2015) highlighted the need for educational investment in this unregistered workforce. As Talent Care team, passion educating Healthcare Support Workers (HCSWs) ensure that they are providing best evidence based practice. part our HCSW Apprenticeship, deliver two speciality simulation days,...
Abstract BackgroundMalaria is responsible for over 435,000 deaths annually, with most cases occurring in sub-Saharan Africa. Detecting the presence of Plasmodium spp. sporozoites (spzs) salivary glands Anopheles vectors parasites using circumsporozoite enzyme-linked immunosorbent assay (csELISA) an important malaria surveillance method. The addition bio-based materials have shown potential to improve adsorption and binding target antigens thus can sensitivity detection analytes immunoassays....
Abstract Background: In characterizing malaria epidemiology, measuring mosquito infectiousness informs the entomological inoculation rate, an important metric of transmission. PCR-based methods have been touted as more sensitive than current “gold-standard” circumsporozoite (CSP) ELISA. Wider application has limited by lack specificity for infectious sporozoite stage. We compared a PCR method detecting parasite’s cytochrome oxidase I (COX-I) gene with ELISA protein identification different...