A5032757290- Metal complexes synthesis and properties
- Click Chemistry and Applications
- Cancer-related Molecular Pathways
- Nanomaterials for catalytic reactions
- Autophagy in Disease and Therapy
- Polyoxometalates: Synthesis and Applications
- Water resources management and optimization
- Synthesis and biological activity
- Cell death mechanisms and regulation
- Dendrimers and Hyperbranched Polymers
- RNA Interference and Gene Delivery
- Nanocluster Synthesis and Applications
- Cancer therapeutics and mechanisms
- Organometallic Complex Synthesis and Catalysis
- Bioactive Compounds and Antitumor Agents
- Quinazolinone synthesis and applications
- DNA and Nucleic Acid Chemistry
- Ferrocene Chemistry and Applications
- Polyamine Metabolism and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Catalytic Processes in Materials Science
- Electrocatalysts for Energy Conversion
- Water Systems and Optimization
- Advanced Photocatalysis Techniques
Stellenbosch University
2011-2023
Alkene epoxidations are an important class of reactions carried out in industry; however, current methods plagued by problems, including high cost, difficulty recovering catalysts, and generation large quantities acidic chlorinated waste. In recent years, nanocatalysts have been considered as robust, heterogeneous alternatives to homogeneous catalysts. This work evaluates silver- base metal-containing olefin epoxidation highlighting the industrial applicability green aspects these catalytic...
Abstract Rhabdomyosarcoma (RMS) forms in skeletal muscle and is the most common soft tissue sarcoma children adolescents. Current treatment associated with debilitating side effects outcomes for patients metastatic disease are dismal. Recently, a novel binuclear palladacycle, AJ-5, was shown to exert potent cytotoxicity melanoma breast cancer present negligible adverse mice. This study investigates anti-cancer activity of AJ-5 alveolar embryonal RMS. IC 50 values ≤ 0.2 µM were determined it...
Despite a good legislative framework, South Africa faces significant challenges in the sustainable provision of adequate and safe water services. To improve situation, Africa's Department Water Affairs (DWA) other sector partners undertook initiatives to assist municipalities with operation management By way example, 2006, municipal engineering oriented electronic Quality Management System (eWQMS) was implemented, providing platform for loading drinking quality data tracking performance key...
Abstract Cisplatin and second-generation alternatives to cisplatin, represent some of the most active clinically useful agents in treatment cancer. However, their application clinic is marred by side-effects drug resistance. We have identified binuclear palladacycle, AJ-5, as a lead anticancer compound with potent activity against advanced melanomas estrogen receptor -positive -negative breast cancers. AJ-5 displayed an IC50 0.2μM melanoma cancer cell lines which was 50 fold less than that...